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Skullcap Lesion

MedGen UID:
414670
•Concept ID:
C2825500
•
Finding

Definition

A neoplastic, inflammatory, or vascular process in the roof of the skull. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkullcap Lesion

Professional guidelines

PubMed

Network-based pharmacology and molecular docking exploring the "Bupleuri Radix-Scutellariae Radix" mechanism of action in the viral hepatitis B treatment.
Long P, Xia Y, Yang Y, Cao J
Medicine (Baltimore) 2022 Dec 2;101(48):e31835. doi: 10.1097/MD.0000000000031835. PMID: 36482557Free PMC Article
Catheter Hydrophone Aberration Correction for Transcranial Histotripsy Treatment of Intracerebral Hemorrhage: Proof-of-Concept.
Gerhardson T, Sukovich JR, Pandey AS, Hall TL, Cain CA, Xu Z
IEEE Trans Ultrason Ferroelectr Freq Control 2017 Nov;64(11):1684-1697. Epub 2017 Aug 31 doi: 10.1109/TUFFC.2017.2748050. PMID: 28880166Free PMC Article
Baicalin as a potentially promising drug for the management of sulfur mustard induced cutaneous complications: a review of molecular mechanisms.
Sahebkar A
Cutan Ocul Toxicol 2012 Sep;31(3):226-34. Epub 2011 Nov 22 doi: 10.3109/15569527.2011.633950. PMID: 22107027

Recent clinical studies

Etiology

Identification and drug resistance of pathogen of ulcerative skin disease and its immune responses and protective efficacy after vaccination in a giant spiny frog, Quasipaa spinosa.
Wang Y, Xie Z
Microb Pathog 2024 Feb;187:106526. Epub 2023 Dec 30 doi: 10.1016/j.micpath.2023.106526. PMID: 38163491
Efficacy of Scutellaria baicalensis for the Treatment of Hand, Foot, and Mouth Disease Associated with Encephalitis in Patients Infected with EV71: A Multicenter, Retrospective Analysis.
Lin H, Zhou J, Lin K, Wang H, Liang Z, Ren X, Huang L, Xia C
Biomed Res Int 2016;2016:5697571. Epub 2016 Oct 20 doi: 10.1155/2016/5697571. PMID: 27840828Free PMC Article
Pseudo alopecia areata caused by skull-caps with metal pin fasteners used by Orthodox Jews in Israel.
Yosefy C, Ronnen M, Edelstein D
Clin Dev Immunol 2003 Jun-Dec;10(2-4):193-5. doi: 10.1080/10446670310001642131. PMID: 14768951Free PMC Article

Diagnosis

Malignant tumors affecting the head and neck region in ancient times: Comprehensive study of the CRAB Database.
Aulestia-Viera PV, Rodrigues-Fernandes CI, Brandão TB, Rocha AC, Vargas PA, Lopes MA, Johnson NW, Kowalski LP, Ribeiro ACP, Santos-Silva AR
Braz Oral Res 2024;38:e014. Epub 2024 Jan 5 doi: 10.1590/1807-3107bor-2024.vol38.0014. PMID: 38198312
Identification and drug resistance of pathogen of ulcerative skin disease and its immune responses and protective efficacy after vaccination in a giant spiny frog, Quasipaa spinosa.
Wang Y, Xie Z
Microb Pathog 2024 Feb;187:106526. Epub 2023 Dec 30 doi: 10.1016/j.micpath.2023.106526. PMID: 38163491
Efficacy of Scutellaria baicalensis for the Treatment of Hand, Foot, and Mouth Disease Associated with Encephalitis in Patients Infected with EV71: A Multicenter, Retrospective Analysis.
Lin H, Zhou J, Lin K, Wang H, Liang Z, Ren X, Huang L, Xia C
Biomed Res Int 2016;2016:5697571. Epub 2016 Oct 20 doi: 10.1155/2016/5697571. PMID: 27840828Free PMC Article
Pseudo alopecia areata caused by skull-caps with metal pin fasteners used by Orthodox Jews in Israel.
Yosefy C, Ronnen M, Edelstein D
Clin Dev Immunol 2003 Jun-Dec;10(2-4):193-5. doi: 10.1080/10446670310001642131. PMID: 14768951Free PMC Article

Therapy

Therapeutic efficacy of Scutellaria baicalensis Georgi against psoriasis-like lesions via regulating the responses of keratinocyte and macrophage.
Wang PW, Lin TY, Yang PM, Fang JY, Li WT, Pan TL
Biomed Pharmacother 2022 Nov;155:113798. Epub 2022 Oct 4 doi: 10.1016/j.biopha.2022.113798. PMID: 36271574
Active compounds present inRosmarinus officinalis leaves andScutellaria baicalensis root evaluated as new therapeutic agents for endometriosis.
Ferella L, Bastón JI, Bilotas MA, Singla JJ, González AM, Olivares CN, Meresman GF
Reprod Biomed Online 2018 Dec;37(6):769-782. Epub 2018 Oct 26 doi: 10.1016/j.rbmo.2018.09.018. PMID: 30446309
Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-κB and MAPK pathways.
Chen Y, Zheng Y, Zhou Z, Wang J
Braz J Med Biol Res 2018 Aug 6;51(10):e7476. doi: 10.1590/1414-431X20187476. PMID: 30088539Free PMC Article
Baicalin Ameliorates Imiquimod-Induced Psoriasis-Like Inflammation in Mice.
Hung CH, Wang CN, Cheng HH, Liao JW, Chen YT, Chao YW, Jiang JL, Lee CC
Planta Med 2018 Oct;84(15):1110-1117. Epub 2018 May 15 doi: 10.1055/a-0622-8242. PMID: 29763944
Baicalin as a potentially promising drug for the management of sulfur mustard induced cutaneous complications: a review of molecular mechanisms.
Sahebkar A
Cutan Ocul Toxicol 2012 Sep;31(3):226-34. Epub 2011 Nov 22 doi: 10.3109/15569527.2011.633950. PMID: 22107027

Clinical prediction guides

Early medical skull surgery for treatment of post-traumatic osteomyelitis 5,000 years ago.
Petrone P, Niola M, Di Lorenzo P, Paternoster M, Graziano V, Quaremba G, Buccelli C
PLoS One 2015;10(5):e0124790. Epub 2015 May 27 doi: 10.1371/journal.pone.0124790. PMID: 26018014Free PMC Article
Effect of Scutellaria flavonoids on KCN-induced damages in rat pheochromocytoma PC12 cells.
Shang YZ, Qin BW, Cheng JJ, Miao H
Indian J Med Res 2008 Jun;127(6):610-5. PMID: 18765882

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