U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Depersonalization

MedGen UID:
4226
Concept ID:
C0011551
Mental or Behavioral Dysfunction
Synonym: Depersonalizations
SNOMED CT: Feels own self is unreal (79499004); Depersonalization (79499004)
 
HPO: HP:5200217

Definition

A psychological experience or symptom characterized by a sense of detachment or estrangement from oneself or one's surroundings. [from HPO]

Professional guidelines

PubMed

Breen JO
Am J Manag Care 2018 Dec 1;24(12):e371-e373. PMID: 30586484
Monsalve-Reyes CS, San Luis-Costas C, Gómez-Urquiza JL, Albendín-García L, Aguayo R, Cañadas-De la Fuente GA
BMC Fam Pract 2018 May 10;19(1):59. doi: 10.1186/s12875-018-0748-z. PMID: 29747579Free PMC Article
Daniels AH, DePasse JM, Kamal RN
J Am Acad Orthop Surg 2016 Apr;24(4):213-9. doi: 10.5435/JAAOS-D-15-00148. PMID: 26885712

Recent clinical studies

Etiology

Lee M, Cha C
Sci Rep 2023 Jul 6;13(1):10971. doi: 10.1038/s41598-023-38169-8. PMID: 37414811Free PMC Article
Rodrigues H, Cobucci R, Oliveira A, Cabral JV, Medeiros L, Gurgel K, Souza T, Gonçalves AK
PLoS One 2018;13(11):e0206840. Epub 2018 Nov 12 doi: 10.1371/journal.pone.0206840. PMID: 30418984Free PMC Article
Monsalve-Reyes CS, San Luis-Costas C, Gómez-Urquiza JL, Albendín-García L, Aguayo R, Cañadas-De la Fuente GA
BMC Fam Pract 2018 May 10;19(1):59. doi: 10.1186/s12875-018-0748-z. PMID: 29747579Free PMC Article
Hogg MA, Rinella MJ
Curr Opin Psychol 2018 Oct;23:6-10. Epub 2017 Nov 4 doi: 10.1016/j.copsyc.2017.10.003. PMID: 29172100
Rosenhan DL
Science 1973 Jan 19;179(4070):250-8. doi: 10.1126/science.179.4070.250. PMID: 4683124

Diagnosis

Fainstad T, Mann A, Suresh K, Shah P, Dieujuste N, Thurmon K, Jones CD
JAMA Netw Open 2022 May 2;5(5):e2210752. doi: 10.1001/jamanetworkopen.2022.10752. PMID: 35522281Free PMC Article
Copur MS
Oncology (Williston Park) 2019 Nov 14;33(11) PMID: 31769864
Villwock JA, Sobin LB, Koester LA, Harris TM
Int J Med Educ 2016 Oct 31;7:364-369. doi: 10.5116/ijme.5801.eac4. PMID: 27802178Free PMC Article
Spiegel D, Lewis-Fernández R, Lanius R, Vermetten E, Simeon D, Friedman M
Annu Rev Clin Psychol 2013;9:299-326. Epub 2013 Feb 1 doi: 10.1146/annurev-clinpsy-050212-185531. PMID: 23394228
Rosenhan DL
Science 1973 Jan 19;179(4070):250-8. doi: 10.1126/science.179.4070.250. PMID: 4683124

Therapy

Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST
JAMA Psychiatry 2022 Dec 1;79(12):1162-1172. doi: 10.1001/jamapsychiatry.2022.3352. PMID: 36260324Free PMC Article
Galanis P, Vraka I, Fragkou D, Bilali A, Kaitelidou D
J Adv Nurs 2021 Aug;77(8):3286-3302. Epub 2021 Mar 25 doi: 10.1111/jan.14839. PMID: 33764561Free PMC Article
Suleiman-Martos N, Gomez-Urquiza JL, Aguayo-Estremera R, Cañadas-De La Fuente GA, De La Fuente-Solana EI, Albendín-García L
J Adv Nurs 2020 May;76(5):1124-1140. Epub 2020 Mar 4 doi: 10.1111/jan.14318. PMID: 32026484
Liechti ME
Neuropsychopharmacology 2017 Oct;42(11):2114-2127. Epub 2017 Apr 27 doi: 10.1038/npp.2017.86. PMID: 28447622Free PMC Article
Alexander GK, Rollins K, Walker D, Wong L, Pennings J
Workplace Health Saf 2015 Oct;63(10):462-70; quiz 471. doi: 10.1177/2165079915596102. PMID: 26419795

Prognosis

López-López IM, Gómez-Urquiza JL, Cañadas GR, De la Fuente EI, Albendín-García L, Cañadas-De la Fuente GA
Int J Ment Health Nurs 2019 Oct;28(5):1032-1041. Epub 2019 May 27 doi: 10.1111/inm.12606. PMID: 31132216
Boissy A, Windover AK, Bokar D, Karafa M, Neuendorf K, Frankel RM, Merlino J, Rothberg MB
J Gen Intern Med 2016 Jul;31(7):755-61. Epub 2016 Feb 26 doi: 10.1007/s11606-016-3597-2. PMID: 26921153Free PMC Article
Alexander GK, Rollins K, Walker D, Wong L, Pennings J
Workplace Health Saf 2015 Oct;63(10):462-70; quiz 471. doi: 10.1177/2165079915596102. PMID: 26419795
Kenna HA, Poon AW, de los Angeles CP, Koran LM
Psychiatry Clin Neurosci 2011 Oct;65(6):549-60. doi: 10.1111/j.1440-1819.2011.02260.x. PMID: 22003987
Dyrbye LN, Thomas MR, Shanafelt TD
Acad Med 2006 Apr;81(4):354-73. doi: 10.1097/00001888-200604000-00009. PMID: 16565188

Clinical prediction guides

Malinauskas R, Grinevicius M, Malinauskiene V
Int J Environ Res Public Health 2022 Sep 7;19(18) doi: 10.3390/ijerph191811249. PMID: 36141531Free PMC Article
Fainstad T, Mann A, Suresh K, Shah P, Dieujuste N, Thurmon K, Jones CD
JAMA Netw Open 2022 May 2;5(5):e2210752. doi: 10.1001/jamanetworkopen.2022.10752. PMID: 35522281Free PMC Article
Boissy A, Windover AK, Bokar D, Karafa M, Neuendorf K, Frankel RM, Merlino J, Rothberg MB
J Gen Intern Med 2016 Jul;31(7):755-61. Epub 2016 Feb 26 doi: 10.1007/s11606-016-3597-2. PMID: 26921153Free PMC Article
Medford N
Epilepsy Behav 2014 Jan;30:10-3. Epub 2013 Nov 4 doi: 10.1016/j.yebeh.2013.09.038. PMID: 24196397
Sierra M, Berrios GE
Biol Psychiatry 1998 Nov 1;44(9):898-908. doi: 10.1016/s0006-3223(98)00015-8. PMID: 9807645

Recent systematic reviews

Rhee TG, Shim SR, Forester BP, Nierenberg AA, McIntyre RS, Papakostas GI, Krystal JH, Sanacora G, Wilkinson ST
JAMA Psychiatry 2022 Dec 1;79(12):1162-1172. doi: 10.1001/jamapsychiatry.2022.3352. PMID: 36260324Free PMC Article
Ramírez-Elvira S, Romero-Béjar JL, Suleiman-Martos N, Gómez-Urquiza JL, Monsalve-Reyes C, Cañadas-De la Fuente GA, Albendín-García L
Int J Environ Res Public Health 2021 Oct 30;18(21) doi: 10.3390/ijerph182111432. PMID: 34769948Free PMC Article
Jun J, Ojemeni MM, Kalamani R, Tong J, Crecelius ML
Int J Nurs Stud 2021 Jul;119:103933. Epub 2021 Mar 26 doi: 10.1016/j.ijnurstu.2021.103933. PMID: 33901940
Galanis P, Vraka I, Fragkou D, Bilali A, Kaitelidou D
J Adv Nurs 2021 Aug;77(8):3286-3302. Epub 2021 Mar 25 doi: 10.1111/jan.14839. PMID: 33764561Free PMC Article
Rotenstein LS, Torre M, Ramos MA, Rosales RC, Guille C, Sen S, Mata DA
JAMA 2018 Sep 18;320(11):1131-1150. doi: 10.1001/jama.2018.12777. PMID: 30326495Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...