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Hepatitis, Animal

MedGen UID:
42423
•Concept ID:
C0019188
•
Disease or Syndrome
Synonyms: Animal Hepatitides; Animal Hepatitis; Hepatitides, Animal

Definition

INFLAMMATION of the LIVER in non-human animals. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHepatitis, Animal

Professional guidelines

PubMed

Chronic hepatitis. Aetiology and current management.
Cooksley WG, Bradbear RA, Halliday JW, Powell LW
Drugs 1984 Jun;27(6):579-84. doi: 10.2165/00003495-198427060-00004. PMID: 6734469

Recent clinical studies

Etiology

Therapeutic effects of AdipoRon on liver inflammation and fibrosis induced by CCl(4) in mice.
Sha M, Gao Y, Deng C, Wan Y, Zhuang Y, Hu X, Wang Y
Int Immunopharmacol 2020 Feb;79:106157. Epub 2020 Jan 5 doi: 10.1016/j.intimp.2019.106157. PMID: 31911372
Sodium butyrate ameliorates S100/FCA-induced autoimmune hepatitis through regulation of intestinal tight junction and toll-like receptor 4 signaling pathway.
Wu JL, Zou JY, Hu ED, Chen DZ, Chen L, Lu FB, Xu LM, Zheng MH, Li H, Huang Y, Jin XY, Gong YW, Lin Z, Wang XD, Zhao MF, Chen YP
Immunol Lett 2017 Oct;190:169-176. Epub 2017 Aug 12 doi: 10.1016/j.imlet.2017.08.005. PMID: 28811235
Chronic hepatitis in Doberman pinschers. A review.
Mandigers PJ, van den Ingh TS, Spee B, Penning LC, Bode P, Rothuizen J
Vet Q 2004 Sep;26(3):98-106. doi: 10.1080/01652176.2004.9695173. PMID: 15559390
Current biochemical studies of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis suggest a new therapeutic approach.
Hookman P, Barkin JS
Am J Gastroenterol 2003 Sep;98(9):2093-7. doi: 10.1111/j.1572-0241.2003.07670.x. PMID: 14499793
Autoimmune hepatitis. Definition--classification--histopathology--immunopathogenesis.
Meyer zum Büschenfelde KH, Dienes HP
Virchows Arch 1996 Sep;429(1):1-12. doi: 10.1007/BF00196814. PMID: 8865847

Diagnosis

Canine Copper-Associated Hepatitis.
Dirksen K, Fieten H
Vet Clin North Am Small Anim Pract 2017 May;47(3):631-644. Epub 2017 Jan 5 doi: 10.1016/j.cvsm.2016.11.011. PMID: 28063745
Autoimmune hepatitis. Definition--classification--histopathology--immunopathogenesis.
Meyer zum Büschenfelde KH, Dienes HP
Virchows Arch 1996 Sep;429(1):1-12. doi: 10.1007/BF00196814. PMID: 8865847
Distinguishing between acute and symptomatic chronic hepatitis B virus infection.
Maruyama T, Schödel F, Iino S, Koike K, Yasuda K, Peterson D, Milich DR
Gastroenterology 1994 Apr;106(4):1006-15. doi: 10.1016/0016-5085(94)90761-7. PMID: 7511551
Current concepts of acute and chronic viral hepatitis.
deBelle RC, Lester R
Pediatr Clin North Am 1975 Nov;22(4):943-61. doi: 10.1016/s0031-3955(16)33217-5. PMID: 172845
Hepatitis-associated antigen.
Shulman NR
Am J Med 1970 Nov;49(5):669-92. doi: 10.1016/s0002-9343(70)80133-4. PMID: 4250361Free PMC Article

Therapy

Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling.
Wan LF, Shen JJ, Wang YH, Zhao W, Fang NY, Yuan X, Xue BY
Sci Rep 2019 Feb 5;9(1):1415. doi: 10.1038/s41598-018-38391-9. PMID: 30723284Free PMC Article
1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) reduces hepatic injury in concanavalin A-treated mice.
Ko YE, Yoon SY, Ly SY, Kim JH, Sohn KY, Kim JW
J Cell Biochem 2018 Feb;119(2):1392-1405. Epub 2017 Nov 16 doi: 10.1002/jcb.26299. PMID: 28749086
Canine Copper-Associated Hepatitis.
Dirksen K, Fieten H
Vet Clin North Am Small Anim Pract 2017 May;47(3):631-644. Epub 2017 Jan 5 doi: 10.1016/j.cvsm.2016.11.011. PMID: 28063745
Chronic hepatitis in Doberman pinschers. A review.
Mandigers PJ, van den Ingh TS, Spee B, Penning LC, Bode P, Rothuizen J
Vet Q 2004 Sep;26(3):98-106. doi: 10.1080/01652176.2004.9695173. PMID: 15559390
Hepatitis-associated antigen.
Shulman NR
Am J Med 1970 Nov;49(5):669-92. doi: 10.1016/s0002-9343(70)80133-4. PMID: 4250361Free PMC Article

Prognosis

Modification of chemokine pathways and immune cell infiltration as a novel therapeutic approach in liver inflammation and fibrosis.
Zimmermann HW, Tacke F
Inflamm Allergy Drug Targets 2011 Dec;10(6):509-36. doi: 10.2174/187152811798104890. PMID: 22150762
Current biochemical studies of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis suggest a new therapeutic approach.
Hookman P, Barkin JS
Am J Gastroenterol 2003 Sep;98(9):2093-7. doi: 10.1111/j.1572-0241.2003.07670.x. PMID: 14499793
Autoimmune hepatitis. Definition--classification--histopathology--immunopathogenesis.
Meyer zum Büschenfelde KH, Dienes HP
Virchows Arch 1996 Sep;429(1):1-12. doi: 10.1007/BF00196814. PMID: 8865847
Hepatocyte regeneration in acute fulminant and nonfulminant hepatitis: a study of proliferating cell nuclear antigen expression.
Wolf HK, Michalopoulos GK
Hepatology 1992 Apr;15(4):707-13. doi: 10.1002/hep.1840150426. PMID: 1372584
Hepatitis-associated antigen.
Shulman NR
Am J Med 1970 Nov;49(5):669-92. doi: 10.1016/s0002-9343(70)80133-4. PMID: 4250361Free PMC Article

Clinical prediction guides

Interobserver Agreement Using Histological Scoring of the Canine Liver.
Lidbury JA, Rodrigues Hoffmann A, Ivanek R, Cullen JM, Porter BF, Oliveira F, Van Winkle TJ, Grinwis GC, Sucholdolski JS, Steiner JM
J Vet Intern Med 2017 May;31(3):778-783. Epub 2017 Mar 14 doi: 10.1111/jvim.14684. PMID: 28295598Free PMC Article
Dynamic metabolic change is indicative of inflammation-induced transformation of hepatic cells.
Peng B, Liu F, Han R, Luo G, Cathopoulis T, Lu K, Li X, Yang L, Liu GY, Cai JC, Shi SL
Int J Biochem Cell Biol 2015 Sep;66:45-58. Epub 2015 Jul 20 doi: 10.1016/j.biocel.2015.07.007. PMID: 26205150
Transforming growth factor beta-1 signalling in canine hepatic diseases: new models for human fibrotic liver pathologies.
Spee B, Arends B, van den Ingh TS, Brinkhof B, Nederbragt H, Ijzer J, Roskams T, Penning LC, Rothuizen J
Liver Int 2006 Aug;26(6):716-25. doi: 10.1111/j.1478-3231.2006.01277.x. PMID: 16842329
Autoimmune hepatitis. Definition--classification--histopathology--immunopathogenesis.
Meyer zum Büschenfelde KH, Dienes HP
Virchows Arch 1996 Sep;429(1):1-12. doi: 10.1007/BF00196814. PMID: 8865847
Animal models of ethanol dependence and liver injury in rats and baboons.
Lieber CS, Decarli LM
Fed Proc 1976 Apr;35(5):1232-6. PMID: 944146

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