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Major depression, single episode

MedGen UID:
44255
•Concept ID:
C0024517
•
Mental or Behavioral Dysfunction
Synonyms: Major depressive disorder, single episode; Single Episode of Major Depressive Disorder
SNOMED CT: Major depression, single episode (36923009); Major depressive disorder, single episode (36923009)

Definition

An episode of depression lasting two or more weeks without an intervening episode of mania. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMajor depression, single episode

Professional guidelines

PubMed

Comorbid Anxiety and Depression: Clinical and Conceptual Consideration and Transdiagnostic Treatment.
Choi KW, Kim YK, Jeon HJ
Adv Exp Med Biol 2020;1191:219-235. doi: 10.1007/978-981-32-9705-0_14. PMID: 32002932
Double-blind, placebo-controlled, dose-ranging trial of intravenous ketamine as adjunctive therapy in treatment-resistant depression (TRD).
Fava M, Freeman MP, Flynn M, Judge H, Hoeppner BB, Cusin C, Ionescu DF, Mathew SJ, Chang LC, Iosifescu DV, Murrough J, Debattista C, Schatzberg AF, Trivedi MH, Jha MK, Sanacora G, Wilkinson ST, Papakostas GI
Mol Psychiatry 2020 Jul;25(7):1592-1603. Epub 2018 Oct 3 doi: 10.1038/s41380-018-0256-5. PMID: 30283029Free PMC Article
Machine learning in major depression: From classification to treatment outcome prediction.
Gao S, Calhoun VD, Sui J
CNS Neurosci Ther 2018 Nov;24(11):1037-1052. Epub 2018 Aug 23 doi: 10.1111/cns.13048. PMID: 30136381Free PMC Article

Recent clinical studies

Etiology

Domestic violence in women with serious mental illness involved with child protective services.
Lewin LC, Abdrbo A, Burant CJ
Issues Ment Health Nurs 2010 Feb;31(2):128-36. doi: 10.3109/01612840903383984. PMID: 20070227
Suicidality and aggressive behaviour.
Castrogiovanni P, Pieraccini F, Di Muro A
Acta Psychiatr Scand 1998 Feb;97(2):144-8. doi: 10.1111/j.1600-0447.1998.tb09977.x. PMID: 9517909
Expanded trinucleotide CAG repeats in families with bipolar affective disorder.
Mendlewicz J, Lindbald K, Souery D, Mahieu B, Nylander PO, De Bruyn A, Zander C, Engström C, Adolfsson R, Van Broeckhoven C, Schalling M, Lipp O
Biol Psychiatry 1997 Dec 15;42(12):1115-22. doi: 10.1016/s0006-3223(97)00395-8. PMID: 9426881

Diagnosis

Impact of citalopram on the HPA system. A study of the combined DEX/CRH test in 30 unipolar depressed patients.
Bschor T, Ising M, Erbe S, Winkelmann P, Ritter D, Uhr M, Lewitzka U
J Psychiatr Res 2012 Jan;46(1):111-7. Epub 2011 Oct 26 doi: 10.1016/j.jpsychires.2011.09.020. PMID: 22030468
Domestic violence in women with serious mental illness involved with child protective services.
Lewin LC, Abdrbo A, Burant CJ
Issues Ment Health Nurs 2010 Feb;31(2):128-36. doi: 10.3109/01612840903383984. PMID: 20070227
The construct of internalization: conceptualization, measurement, and prediction of smoking treatment outcome.
Acton GS, Kunz JD, Wilson M, Hall SM
Psychol Med 2005 Mar;35(3):395-408. doi: 10.1017/s0033291704003083. PMID: 15841875
Suicidality and aggressive behaviour.
Castrogiovanni P, Pieraccini F, Di Muro A
Acta Psychiatr Scand 1998 Feb;97(2):144-8. doi: 10.1111/j.1600-0447.1998.tb09977.x. PMID: 9517909
Efficacy of tianeptine in comparative trials versus reference antidepressants. An overview.
Guelfi JD
Br J Psychiatry Suppl 1992 Feb;(15):72-5. PMID: 1389026

Therapy

Impact of citalopram on the HPA system. A study of the combined DEX/CRH test in 30 unipolar depressed patients.
Bschor T, Ising M, Erbe S, Winkelmann P, Ritter D, Uhr M, Lewitzka U
J Psychiatr Res 2012 Jan;46(1):111-7. Epub 2011 Oct 26 doi: 10.1016/j.jpsychires.2011.09.020. PMID: 22030468
Lithium monotherapy increases ACTH and cortisol response in the DEX/CRH test in unipolar depressed subjects. A study with 30 treatment-naive patients.
Bschor T, Ritter D, Winkelmann P, Erbe S, Uhr M, Ising M, Lewitzka U
PLoS One 2011;6(11):e27613. Epub 2011 Nov 23 doi: 10.1371/journal.pone.0027613. PMID: 22132117Free PMC Article
The construct of internalization: conceptualization, measurement, and prediction of smoking treatment outcome.
Acton GS, Kunz JD, Wilson M, Hall SM
Psychol Med 2005 Mar;35(3):395-408. doi: 10.1017/s0033291704003083. PMID: 15841875
Alternative treatments for depression: empirical support and relevance to women.
Manber R, Allen JJ, Morris ME
J Clin Psychiatry 2002 Jul;63(7):628-40. doi: 10.4088/jcp.v63n0716. PMID: 12143922
Efficacy of tianeptine in comparative trials versus reference antidepressants. An overview.
Guelfi JD
Br J Psychiatry Suppl 1992 Feb;(15):72-5. PMID: 1389026

Prognosis

The construct of internalization: conceptualization, measurement, and prediction of smoking treatment outcome.
Acton GS, Kunz JD, Wilson M, Hall SM
Psychol Med 2005 Mar;35(3):395-408. doi: 10.1017/s0033291704003083. PMID: 15841875

Clinical prediction guides

Impact of citalopram on the HPA system. A study of the combined DEX/CRH test in 30 unipolar depressed patients.
Bschor T, Ising M, Erbe S, Winkelmann P, Ritter D, Uhr M, Lewitzka U
J Psychiatr Res 2012 Jan;46(1):111-7. Epub 2011 Oct 26 doi: 10.1016/j.jpsychires.2011.09.020. PMID: 22030468
The construct of internalization: conceptualization, measurement, and prediction of smoking treatment outcome.
Acton GS, Kunz JD, Wilson M, Hall SM
Psychol Med 2005 Mar;35(3):395-408. doi: 10.1017/s0033291704003083. PMID: 15841875
Expanded trinucleotide CAG repeats in families with bipolar affective disorder.
Mendlewicz J, Lindbald K, Souery D, Mahieu B, Nylander PO, De Bruyn A, Zander C, Engström C, Adolfsson R, Van Broeckhoven C, Schalling M, Lipp O
Biol Psychiatry 1997 Dec 15;42(12):1115-22. doi: 10.1016/s0006-3223(97)00395-8. PMID: 9426881

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