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Parageusia

MedGen UID:
4428
•Concept ID:
C0013378
•
Finding
Synonyms: Distorted Taste; Dysgeusia; Dysgeusias; Taste, Distorted
SNOMED CT: Gustatory alteration (36955009); Taste sense altered (271801002); Perversion of sense of taste (271801002); Things taste different (271801002); Adverse taste perception (271801002); Things taste abnormal (271801002); Distorted taste (271801002); Parageusia (271801002); Disordered taste (271801002); Things taste peculiar (271801002); Dysgeusia (271801002)
 
HPO: HP:0031249

Definition

A distortion of the sense of taste, often characterized by the sensation of a metallic taste. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParageusia

Professional guidelines

PubMed

Part Two: Perspectives on Olfactory and Gustatory Dysfunction Pathophysiology, Management, and Relevance to COVID-19: Current Approaches.
Liebell D
Altern Ther Health Med 2023 Sep;29(6):30-35. PMID: 37574205
Perspectives on the Pathophysiology, Management, and Relevance of Olfactory and Gustatory Dysfunction to COVID-19, Part One.
Liebell D
Altern Ther Health Med 2023 Mar;29(2):76-81. PMID: 36689356
The Relationship between Malnutrition and Subjective Taste Change Experienced by Patients with Cancer Receiving Outpatient Chemotherapy Treatment.
Özkan İ, Taylan S, Eroğlu N, Kolaç N
Nutr Cancer 2022;74(5):1670-1679. Epub 2021 Jul 30 doi: 10.1080/01635581.2021.1957485. PMID: 34328368

Recent clinical studies

Etiology

The Relationship between Malnutrition and Subjective Taste Change Experienced by Patients with Cancer Receiving Outpatient Chemotherapy Treatment.
Özkan İ, Taylan S, Eroğlu N, Kolaç N
Nutr Cancer 2022;74(5):1670-1679. Epub 2021 Jul 30 doi: 10.1080/01635581.2021.1957485. PMID: 34328368
Prospective assessment of taste impairment and nausea during radiotherapy for head and neck cancer.
Martini S, Iorio GC, Arcadipane F, Olivero F, Silvetti P, Rampino M, Garzino Demo P, Fasolis M, Pecorari G, Airoldi M, Ricardi U, Franco P
Med Oncol 2019 Apr 9;36(5):44. doi: 10.1007/s12032-019-1269-x. PMID: 30968205
Relationship between subjective taste alteration and weight loss in head and neck cancer patients treated with radiotherapy: A longitudinal study.
Jin S, Lu Q, Jin S, Zhang L, Cui H, Li H
Eur J Oncol Nurs 2018 Dec;37:43-50. Epub 2018 Oct 12 doi: 10.1016/j.ejon.2018.10.003. PMID: 30473050
Characteristics of taste disorders.
Fark T, Hummel C, Hähner A, Nin T, Hummel T
Eur Arch Otorhinolaryngol 2013 May;270(6):1855-60. Epub 2012 Dec 11 doi: 10.1007/s00405-012-2310-2. PMID: 23229645
Taste disturbance following tonsillectomy--a prospective study.
Heiser C, Landis BN, Giger R, Cao Van H, Guinand N, Hörmann K, Stuck BA
Laryngoscope 2010 Oct;120(10):2119-24. doi: 10.1002/lary.20971. PMID: 20824635

Diagnosis

Olfactory and taste dysfunctions caused by COVID-19: a nationwide study.
Miwa T, Mori E, Sekine R, Kimura Y, Kobayashi M, Shiga H, Tsuzuki K, Suzuki M, Kondo K, Suzaki I, Inokuchi G, Aiba T, Chujo K, Yagi-Nakanishi S, Tsukatani T, Nakanishi H, Nishijo M, Iinuma Y, Yokoyama A
Rhinology 2023 Dec 1;61(6):552-560. doi: 10.4193/Rhin23.034. PMID: 37690065
Occurrence of Dysgeusia in Patients Being Treated for Cancer.
Di Meglio J, Dinu M, Doni L, Rossi G, Giorgione R, Colombini B, Antonuzzo L, Sofi F
Nutr Cancer 2022;74(8):2868-2874. Epub 2022 Feb 23 doi: 10.1080/01635581.2022.2042569. PMID: 35196919
Qualitative smell/taste disorders as sequelae of acute COVID-19.
Ercoli T, Masala C, Pinna I, Orofino G, Solla P, Rocchi L, Defazio G
Neurol Sci 2021 Dec;42(12):4921-4926. Epub 2021 Sep 23 doi: 10.1007/s10072-021-05611-6. PMID: 34557966Free PMC Article
Olfactory and gustatory dysfunctions due to the coronavirus disease (COVID-19): a review of current evidence.
Mehraeen E, Behnezhad F, Salehi MA, Noori T, Harandi H, SeyedAlinaghi S
Eur Arch Otorhinolaryngol 2021 Feb;278(2):307-312. Epub 2020 Jun 17 doi: 10.1007/s00405-020-06120-6. PMID: 32556781Free PMC Article
Characteristics of taste disorders.
Fark T, Hummel C, Hähner A, Nin T, Hummel T
Eur Arch Otorhinolaryngol 2013 May;270(6):1855-60. Epub 2012 Dec 11 doi: 10.1007/s00405-012-2310-2. PMID: 23229645

Therapy

Occurrence of Dysgeusia in Patients Being Treated for Cancer.
Di Meglio J, Dinu M, Doni L, Rossi G, Giorgione R, Colombini B, Antonuzzo L, Sofi F
Nutr Cancer 2022;74(8):2868-2874. Epub 2022 Feb 23 doi: 10.1080/01635581.2022.2042569. PMID: 35196919
Successful Management of Glioblastoma Chemotherapy-Associated Dysgeusia with Gabapentin.
Turcotte K, Touchette CJ, Iorio-Morin C, Fortin D
Can J Neurol Sci 2020 Nov;47(6):839-841. Epub 2020 Jun 5 doi: 10.1017/cjn.2020.115. PMID: 32498727
Prospective assessment of taste impairment and nausea during radiotherapy for head and neck cancer.
Martini S, Iorio GC, Arcadipane F, Olivero F, Silvetti P, Rampino M, Garzino Demo P, Fasolis M, Pecorari G, Airoldi M, Ricardi U, Franco P
Med Oncol 2019 Apr 9;36(5):44. doi: 10.1007/s12032-019-1269-x. PMID: 30968205
The Validity and Reliability of Turkish Version of the Chemotherapy-induced Taste Alteration Scale (CiTAS).
Sozeri E, Kutluturkan S
Clin Nurs Res 2018 Feb;27(2):235-249. Epub 2016 Aug 11 doi: 10.1177/1054773816662436. PMID: 27514732
Taste disturbance following tonsillectomy--a prospective study.
Heiser C, Landis BN, Giger R, Cao Van H, Guinand N, Hörmann K, Stuck BA
Laryngoscope 2010 Oct;120(10):2119-24. doi: 10.1002/lary.20971. PMID: 20824635

Prognosis

Post-COVID syndrome: analysis of the prevalence of chemosensory dysfunction and predictive factors of recovery in COVID-19 long-haulers in Jordan.
Sawan HM, Khalifeh AH, Ahmed M, Khalil MM, Al Omari SM, Binsuwaidan R
Eur Rev Med Pharmacol Sci 2024 Mar;28(6):2593-2604. doi: 10.26355/eurrev_202403_35765. PMID: 38567618
Taste disturbance following tonsillectomy--a prospective study.
Heiser C, Landis BN, Giger R, Cao Van H, Guinand N, Hörmann K, Stuck BA
Laryngoscope 2010 Oct;120(10):2119-24. doi: 10.1002/lary.20971. PMID: 20824635

Clinical prediction guides

Olfactory and taste dysfunctions caused by COVID-19: a nationwide study.
Miwa T, Mori E, Sekine R, Kimura Y, Kobayashi M, Shiga H, Tsuzuki K, Suzuki M, Kondo K, Suzaki I, Inokuchi G, Aiba T, Chujo K, Yagi-Nakanishi S, Tsukatani T, Nakanishi H, Nishijo M, Iinuma Y, Yokoyama A
Rhinology 2023 Dec 1;61(6):552-560. doi: 10.4193/Rhin23.034. PMID: 37690065
Evaluation of qualitative and quantitative taste alterations in COVID-19.
Cazzolla AP, Lovero R, Spirito F, Di Cosola M, Santacroce L, Lo Muzio E, Ciavarella D, Dioguardi M, Crincoli V, Pepe M, Varraso L, Contino R, Di Serio F, Lo Muzio L
Biomol Biomed 2023 Mar 16;23(2):344-350. doi: 10.17305/bjbms.2022.6973. PMID: 35801415Free PMC Article
Occurrence of Dysgeusia in Patients Being Treated for Cancer.
Di Meglio J, Dinu M, Doni L, Rossi G, Giorgione R, Colombini B, Antonuzzo L, Sofi F
Nutr Cancer 2022;74(8):2868-2874. Epub 2022 Feb 23 doi: 10.1080/01635581.2022.2042569. PMID: 35196919
Qualitative smell/taste disorders as sequelae of acute COVID-19.
Ercoli T, Masala C, Pinna I, Orofino G, Solla P, Rocchi L, Defazio G
Neurol Sci 2021 Dec;42(12):4921-4926. Epub 2021 Sep 23 doi: 10.1007/s10072-021-05611-6. PMID: 34557966Free PMC Article
Prospective assessment of taste impairment and nausea during radiotherapy for head and neck cancer.
Martini S, Iorio GC, Arcadipane F, Olivero F, Silvetti P, Rampino M, Garzino Demo P, Fasolis M, Pecorari G, Airoldi M, Ricardi U, Franco P
Med Oncol 2019 Apr 9;36(5):44. doi: 10.1007/s12032-019-1269-x. PMID: 30968205

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