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Focal Mammary Duct Ectasia

MedGen UID:
443273
•Concept ID:
C2826599
•
Disease or Syndrome

Definition

Localized widening of the lumen of the mammary ducts. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal Mammary Duct Ectasia

Professional guidelines

PubMed

Diagnosis and surgical treatment of pathologic nipple discharge using ultrasound-guided wire localization of focal ductal dilatation.
Ali Mlees M
Breast J 2020 Feb;26(2):139-143. Epub 2019 Sep 11 doi: 10.1111/tbj.13493. PMID: 31512354
Ultrasound-guided wire localization of focal ductal dilatation in the evaluation and treatment of pathologic nipple discharge.
Romanoff A, Nulsen B, Mester J, Jaffer S, Weltz C
Breast J 2018 May;24(3):356-359. Epub 2017 Oct 24 doi: 10.1111/tbj.12936. PMID: 29063655
Imaging approaches to diagnosis and management of common ductal abnormalities.
Ferris-James DM, Iuanow E, Mehta TS, Shaheen RM, Slanetz PJ
Radiographics 2012 Jul-Aug;32(4):1009-30. doi: 10.1148/rg.324115150. PMID: 22786991

Recent clinical studies

Etiology

Sonographic Evaluation of Nigerian Women with Mammographic Focal Asymmetric Density.
Itanyi DU, Ibrahim H, Ka'alu WO
West Afr J Med 2024 Mar 29;41(3):233-237. PMID: 38785292
Imaging features of granulomatous mastitis in 36 patients with new sonographic signs.
Alikhassi A, Azizi F, Ensani F
J Ultrasound 2020 Mar;23(1):61-68. Epub 2019 Jun 7 doi: 10.1007/s40477-019-00392-3. PMID: 31175613Free PMC Article
Ultrasound-guided wire localization of focal ductal dilatation in the evaluation and treatment of pathologic nipple discharge.
Romanoff A, Nulsen B, Mester J, Jaffer S, Weltz C
Breast J 2018 May;24(3):356-359. Epub 2017 Oct 24 doi: 10.1111/tbj.12936. PMID: 29063655
Adjunctive diagnostic value of ultrasonography evaluation in patients with suspected ductal breast disease.
Ballesio L, Maggi C, Savelli S, Angeletti M, Rabuffi P, Manganaro L, Porfiri LM
Radiol Med 2007 Apr;112(3):354-65. Epub 2007 Apr 20 doi: 10.1007/s11547-007-0146-4. PMID: 17440697
Preoperative galactography increases the diagnostic yield of major duct excision for nipple discharge.
Van Zee KJ, Ortega Pérez G, Minnard E, Cohen MA
Cancer 1998 May 15;82(10):1874-80. doi: 10.1002/(sici)1097-0142(19980515)82:10<1874::aid-cncr9>3.3.co;2-o. PMID: 9587119

Diagnosis

A comparative analysis of diagnostic values of high-frequency ultrasound and fiberoptic ductoscopy for pathologic nipple discharge.
Yuan H, Tang X, Mou X, Fan Y, Yan X, Li J, Hou L, Ren M
BMC Med Imaging 2022 Sep 2;22(1):155. doi: 10.1186/s12880-022-00885-4. PMID: 36056332Free PMC Article
Diagnosis and surgical treatment of pathologic nipple discharge using ultrasound-guided wire localization of focal ductal dilatation.
Ali Mlees M
Breast J 2020 Feb;26(2):139-143. Epub 2019 Sep 11 doi: 10.1111/tbj.13493. PMID: 31512354
Imaging features of granulomatous mastitis in 36 patients with new sonographic signs.
Alikhassi A, Azizi F, Ensani F
J Ultrasound 2020 Mar;23(1):61-68. Epub 2019 Jun 7 doi: 10.1007/s40477-019-00392-3. PMID: 31175613Free PMC Article
Ultra structural changes occurring in duct ectasia and periductal mastitis and their significance in etiopathogenesis.
Ramalingam K, Vuthaluru S, Srivastava A, Dinda AK, Dhar A
PLoS One 2017;12(3):e0173216. Epub 2017 Mar 8 doi: 10.1371/journal.pone.0173216. PMID: 28273122Free PMC Article
Breast ultrasound and new technologies.
Rizzatto G, Chersevani R
Eur J Radiol 1998 May;27 Suppl 2:S242-9. doi: 10.1016/s0720-048x(98)00070-9. PMID: 9652529

Therapy

Celiac axis stenosis due to median arcuate ligament compression in a patient who underwent pancreatoduodenectomy; intraoperative assessment of hepatic arterial flow using Doppler ultrasonography: a case report.
Yamamoto M, Itamoto T, Oshita A, Matsugu Y
J Med Case Rep 2018 Apr 11;12(1):92. doi: 10.1186/s13256-018-1614-2. PMID: 29642943Free PMC Article
Accessory breast tissue in axilla masquerading as breast cancer recurrence.
Goyal S, Puri T, Gupta R, Julka PK, Rath GK
J Cancer Res Ther 2008 Apr-Jun;4(2):95-6. doi: 10.4103/0973-1482.42258. PMID: 18688128
A safe technique of major mammary duct excision.
Srivastava A, Griwan MS, Samaiyar SS, Sharma LK
J R Coll Surg Edinb 1995 Feb;40(1):35-7. PMID: 7738895

Prognosis

Clinical Significance of Contrast-Enhanced Ultrasound Galactography in Pre-operative Diagnosis of Patients With Pathologic Nipple Discharge.
Jiang B, Gao Y, Yu H, Hu X, Tan X, Qiu L, Zhang H, Liu J, Ma X, Qu X
Ultrasound Med Biol 2024 Feb;50(2):191-197. Epub 2023 Nov 7 doi: 10.1016/j.ultrasmedbio.2023.09.017. PMID: 37940461
A comparative analysis of diagnostic values of high-frequency ultrasound and fiberoptic ductoscopy for pathologic nipple discharge.
Yuan H, Tang X, Mou X, Fan Y, Yan X, Li J, Hou L, Ren M
BMC Med Imaging 2022 Sep 2;22(1):155. doi: 10.1186/s12880-022-00885-4. PMID: 36056332Free PMC Article
Adjunctive diagnostic value of ultrasonography evaluation in patients with suspected ductal breast disease.
Ballesio L, Maggi C, Savelli S, Angeletti M, Rabuffi P, Manganaro L, Porfiri LM
Radiol Med 2007 Apr;112(3):354-65. Epub 2007 Apr 20 doi: 10.1007/s11547-007-0146-4. PMID: 17440697
Preoperative galactography increases the diagnostic yield of major duct excision for nipple discharge.
Van Zee KJ, Ortega Pérez G, Minnard E, Cohen MA
Cancer 1998 May 15;82(10):1874-80. doi: 10.1002/(sici)1097-0142(19980515)82:10<1874::aid-cncr9>3.3.co;2-o. PMID: 9587119
Ductal adenoma of the breast--a review of fifteen cases.
Lammie GA, Millis RR
Hum Pathol 1989 Sep;20(9):903-8. doi: 10.1016/0046-8177(89)90104-4. PMID: 2550351

Clinical prediction guides

Sonographic Evaluation of Nigerian Women with Mammographic Focal Asymmetric Density.
Itanyi DU, Ibrahim H, Ka'alu WO
West Afr J Med 2024 Mar 29;41(3):233-237. PMID: 38785292
Clinical Significance of Contrast-Enhanced Ultrasound Galactography in Pre-operative Diagnosis of Patients With Pathologic Nipple Discharge.
Jiang B, Gao Y, Yu H, Hu X, Tan X, Qiu L, Zhang H, Liu J, Ma X, Qu X
Ultrasound Med Biol 2024 Feb;50(2):191-197. Epub 2023 Nov 7 doi: 10.1016/j.ultrasmedbio.2023.09.017. PMID: 37940461
A comparative analysis of diagnostic values of high-frequency ultrasound and fiberoptic ductoscopy for pathologic nipple discharge.
Yuan H, Tang X, Mou X, Fan Y, Yan X, Li J, Hou L, Ren M
BMC Med Imaging 2022 Sep 2;22(1):155. doi: 10.1186/s12880-022-00885-4. PMID: 36056332Free PMC Article
Ultra structural changes occurring in duct ectasia and periductal mastitis and their significance in etiopathogenesis.
Ramalingam K, Vuthaluru S, Srivastava A, Dinda AK, Dhar A
PLoS One 2017;12(3):e0173216. Epub 2017 Mar 8 doi: 10.1371/journal.pone.0173216. PMID: 28273122Free PMC Article
Adjunctive diagnostic value of ultrasonography evaluation in patients with suspected ductal breast disease.
Ballesio L, Maggi C, Savelli S, Angeletti M, Rabuffi P, Manganaro L, Porfiri LM
Radiol Med 2007 Apr;112(3):354-65. Epub 2007 Apr 20 doi: 10.1007/s11547-007-0146-4. PMID: 17440697

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