U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Substance Withdrawal Delirium

MedGen UID:
457451
Concept ID:
C2985225
Mental or Behavioral Dysfunction

Definition

A disorder characterized by the acute and sudden development of changes in attention, memory, language and/or perception that can be etiologically linked to the direct physiological consequences of substance withdrawal. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubstance Withdrawal Delirium

Professional guidelines

PubMed

Day E, Daly C
Addiction 2022 Mar;117(3):804-814. Epub 2021 Aug 22 doi: 10.1111/add.15647. PMID: 34288186
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article
Schuckit MA
N Engl J Med 2014 Nov 27;371(22):2109-13. doi: 10.1056/NEJMra1407298. PMID: 25427113

Recent clinical studies

Etiology

Nisavic M, Nejad SH, Isenberg BM, Bajwa EK, Currier P, Wallace PM, Velmahos G, Wilens T
Psychosomatics 2019 Sep-Oct;60(5):458-467. Epub 2019 Feb 14 doi: 10.1016/j.psym.2019.02.002. PMID: 30876654
Airagnes G, Ducoutumany G, Laffy-Beaufils B, Le Faou AL, Limosin F
Rev Med Interne 2019 Jun;40(6):373-379. Epub 2019 Mar 7 doi: 10.1016/j.revmed.2019.02.001. PMID: 30853380
Attilia F, Perciballi R, Rotondo C, Capriglione I, Iannuzzi S, Attilia ML, Coriale G, Vitali M, Cereatti F, Fiore M, Ceccanti M; Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip
Riv Psichiatr 2018 May-Jun;53(3):118-122. doi: 10.1708/2925.29413. PMID: 29912213
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article
Dixit D, Endicott J, Burry L, Ramos L, Yeung SY, Devabhakthuni S, Chan C, Tobia A, Bulloch MN
Pharmacotherapy 2016 Jul;36(7):797-822. Epub 2016 Jun 30 doi: 10.1002/phar.1770. PMID: 27196747

Diagnosis

Attilia F, Perciballi R, Rotondo C, Capriglione I, Iannuzzi S, Attilia ML, Coriale G, Vitali M, Cereatti F, Fiore M, Ceccanti M; Interdisciplinary Study Group CRARL - SITAC - SIPaD - SITD - SIPDip
Riv Psichiatr 2018 May-Jun;53(3):118-122. doi: 10.1708/2925.29413. PMID: 29912213
Jesse S, Bråthen G, Ferrara M, Keindl M, Ben-Menachem E, Tanasescu R, Brodtkorb E, Hillbom M, Leone MA, Ludolph AC
Acta Neurol Scand 2017 Jan;135(1):4-16. Epub 2016 Sep 1 doi: 10.1111/ane.12671. PMID: 27586815Free PMC Article
Mirijello A, D'Angelo C, Ferrulli A, Vassallo G, Antonelli M, Caputo F, Leggio L, Gasbarrini A, Addolorato G
Drugs 2015 Mar;75(4):353-65. doi: 10.1007/s40265-015-0358-1. PMID: 25666543Free PMC Article
Schuckit MA
N Engl J Med 2014 Nov 27;371(22):2109-13. doi: 10.1056/NEJMra1407298. PMID: 25427113
Schuckit MA
Lancet 2009 Feb 7;373(9662):492-501. Epub 2009 Jan 23 doi: 10.1016/S0140-6736(09)60009-X. PMID: 19168210

Therapy

Day E, Daly C
Addiction 2022 Mar;117(3):804-814. Epub 2021 Aug 22 doi: 10.1111/add.15647. PMID: 34288186
Farrokh S, Roels C, Owusu KA, Nelson SE, Cook AM
Neurocrit Care 2021 Apr;34(2):593-607. Epub 2020 Aug 13 doi: 10.1007/s12028-020-01061-8. PMID: 32794143
Airagnes G, Ducoutumany G, Laffy-Beaufils B, Le Faou AL, Limosin F
Rev Med Interne 2019 Jun;40(6):373-379. Epub 2019 Mar 7 doi: 10.1016/j.revmed.2019.02.001. PMID: 30853380
Dixit D, Endicott J, Burry L, Ramos L, Yeung SY, Devabhakthuni S, Chan C, Tobia A, Bulloch MN
Pharmacotherapy 2016 Jul;36(7):797-822. Epub 2016 Jun 30 doi: 10.1002/phar.1770. PMID: 27196747
Mirijello A, D'Angelo C, Ferrulli A, Vassallo G, Antonelli M, Caputo F, Leggio L, Gasbarrini A, Addolorato G
Drugs 2015 Mar;75(4):353-65. doi: 10.1007/s40265-015-0358-1. PMID: 25666543Free PMC Article

Prognosis

Farrokh S, Roels C, Owusu KA, Nelson SE, Cook AM
Neurocrit Care 2021 Apr;34(2):593-607. Epub 2020 Aug 13 doi: 10.1007/s12028-020-01061-8. PMID: 32794143
Silczuk A, Habrat B
Alcohol 2020 Aug;86:9-16. Epub 2020 Apr 21 doi: 10.1016/j.alcohol.2020.02.166. PMID: 32330589
Wood E, Albarqouni L, Tkachuk S, Green CJ, Ahamad K, Nolan S, McLean M, Klimas J
JAMA 2018 Aug 28;320(8):825-833. doi: 10.1001/jama.2018.10574. PMID: 30167704Free PMC Article
Singal AK, Bataller R, Ahn J, Kamath PS, Shah VH
Am J Gastroenterol 2018 Feb;113(2):175-194. Epub 2018 Jan 16 doi: 10.1038/ajg.2017.469. PMID: 29336434Free PMC Article
Maldonado JR, Sher Y, Ashouri JF, Hills-Evans K, Swendsen H, Lolak S, Miller AC
Alcohol 2014 Jun;48(4):375-90. Epub 2014 Feb 19 doi: 10.1016/j.alcohol.2014.01.004. PMID: 24657098

Clinical prediction guides

Bahji A, Bach P, Danilewitz M, Crockford D, El-Guebaly N, Devoe DJ, Saitz R
Addiction 2022 Oct;117(10):2591-2601. Epub 2022 Mar 15 doi: 10.1111/add.15853. PMID: 35194860Free PMC Article
Farrokh S, Roels C, Owusu KA, Nelson SE, Cook AM
Neurocrit Care 2021 Apr;34(2):593-607. Epub 2020 Aug 13 doi: 10.1007/s12028-020-01061-8. PMID: 32794143
Wood E, Albarqouni L, Tkachuk S, Green CJ, Ahamad K, Nolan S, McLean M, Klimas J
JAMA 2018 Aug 28;320(8):825-833. doi: 10.1001/jama.2018.10574. PMID: 30167704Free PMC Article
Salluh JI, Wang H, Schneider EB, Nagaraja N, Yenokyan G, Damluji A, Serafim RB, Stevens RD
BMJ 2015 Jun 3;350:h2538. doi: 10.1136/bmj.h2538. PMID: 26041151Free PMC Article
Maldonado JR, Sher Y, Ashouri JF, Hills-Evans K, Swendsen H, Lolak S, Miller AC
Alcohol 2014 Jun;48(4):375-90. Epub 2014 Feb 19 doi: 10.1016/j.alcohol.2014.01.004. PMID: 24657098

Recent systematic reviews

Bahji A, Bach P, Danilewitz M, Crockford D, El-Guebaly N, Devoe DJ, Saitz R
Addiction 2022 Oct;117(10):2591-2601. Epub 2022 Mar 15 doi: 10.1111/add.15853. PMID: 35194860Free PMC Article
Wood E, Albarqouni L, Tkachuk S, Green CJ, Ahamad K, Nolan S, McLean M, Klimas J
JAMA 2018 Aug 28;320(8):825-833. doi: 10.1001/jama.2018.10574. PMID: 30167704Free PMC Article
Salluh JI, Wang H, Schneider EB, Nagaraja N, Yenokyan G, Damluji A, Serafim RB, Stevens RD
BMJ 2015 Jun 3;350:h2538. doi: 10.1136/bmj.h2538. PMID: 26041151Free PMC Article
Maldonado JR, Sher Y, Ashouri JF, Hills-Evans K, Swendsen H, Lolak S, Miller AC
Alcohol 2014 Jun;48(4):375-90. Epub 2014 Feb 19 doi: 10.1016/j.alcohol.2014.01.004. PMID: 24657098
Friedman JI, Soleimani L, McGonigle DP, Egol C, Silverstein JH
Am J Psychiatry 2014 Feb;171(2):151-9. doi: 10.1176/appi.ajp.2013.13040458. PMID: 24362367

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...