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Multicentric Lesion

MedGen UID:
458889
•Concept ID:
C2986663
•
Finding

Definition

A term that usually refers to cancer growth and is defined by the presence of multiple lesions, each originating from a different clonal cellular population. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMulticentric Lesion

Professional guidelines

PubMed

Pre-treatment MRI tumor features and post-treatment mammographic findings: may they contribute to refining the prediction of pathologic complete response in post-neoadjuvant breast cancer patients with radiologic complete response on MRI?
Thompson BM, Chala LF, Shimizu C, Mano MS, Filassi JR, Geyer FC, Torres US, de Mello GGN, da Costa Leite C
Eur Radiol 2022 Mar;32(3):1663-1675. Epub 2021 Oct 30 doi: 10.1007/s00330-021-08290-1. PMID: 34716780
Human papillomavirus genotypes and the risk factors associated with multicentric intraepithelial lesions of the lower genital tract: a retrospective study.
Zhang J, Liu G, Cui X, Yu H, Wang D
BMC Infect Dis 2021 Jun 11;21(1):554. doi: 10.1186/s12879-021-06234-0. PMID: 34116658Free PMC Article
Multicentric glioblastomas. Methods of diagnosis and treatment.
Schiefer W, Hasenbein B, Schmidt H
Acta Neurochir (Wien) 1978;42(1-2):89-95. doi: 10.1007/BF01406634. PMID: 211811

Recent clinical studies

Etiology

Impact of preoperative staging with contrast-enhanced mammography for localized breast cancer management.
Montrognon F, Clatot F, Berghian A, Douvrin F, Quieffin F, Defta D, Buquet A, Ferret M, Lequesne J, Leheurteur M, Fontanilles M, Georgescu D, Callonnec F
Br J Radiol 2022 Jun 1;95(1134):20210765. Epub 2022 Mar 9 doi: 10.1259/bjr.20210765. PMID: 35195454Free PMC Article
Pre-treatment MRI tumor features and post-treatment mammographic findings: may they contribute to refining the prediction of pathologic complete response in post-neoadjuvant breast cancer patients with radiologic complete response on MRI?
Thompson BM, Chala LF, Shimizu C, Mano MS, Filassi JR, Geyer FC, Torres US, de Mello GGN, da Costa Leite C
Eur Radiol 2022 Mar;32(3):1663-1675. Epub 2021 Oct 30 doi: 10.1007/s00330-021-08290-1. PMID: 34716780
Human papillomavirus genotypes and the risk factors associated with multicentric intraepithelial lesions of the lower genital tract: a retrospective study.
Zhang J, Liu G, Cui X, Yu H, Wang D
BMC Infect Dis 2021 Jun 11;21(1):554. doi: 10.1186/s12879-021-06234-0. PMID: 34116658Free PMC Article
The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study.
González-Huebra I, Malmierca P, Elizalde A, Etxano J, Vejborg I, Uhlenbrock D, Pina L
Acta Radiol 2020 Oct;61(10):1335-1342. Epub 2020 Jan 24 doi: 10.1177/0284185119900440. PMID: 31979977
Risk factors to develop multicentric lesions of the lower genital tract.
Gonzalez-Bosquet E, Mazarico E, Lorente N, Gomez-Roig MD
Eur J Gynaecol Oncol 2017;38(1):10-13. PMID: 29767857

Diagnosis

Human papillomavirus genotypes and the risk factors associated with multicentric intraepithelial lesions of the lower genital tract: a retrospective study.
Zhang J, Liu G, Cui X, Yu H, Wang D
BMC Infect Dis 2021 Jun 11;21(1):554. doi: 10.1186/s12879-021-06234-0. PMID: 34116658Free PMC Article
The accuracy of titanium contrast-enhanced mammography: a retrospective multicentric study.
González-Huebra I, Malmierca P, Elizalde A, Etxano J, Vejborg I, Uhlenbrock D, Pina L
Acta Radiol 2020 Oct;61(10):1335-1342. Epub 2020 Jan 24 doi: 10.1177/0284185119900440. PMID: 31979977
Comparison of 3-Tesla to 1.5-Tesla Magnetic Resonance Enterography to assess multifocal and multicentric bowel endometriosis: Results in routine practice.
Allègre L, Aristizabal P, Nyangoh Timoh K, Thomassin-Naggara I, Kermarrec E, Bendifallah S, Darai E
Eur J Obstet Gynecol Reprod Biol 2018 Nov;230:172-177. Epub 2018 Sep 25 doi: 10.1016/j.ejogrb.2018.09.035. PMID: 30292947
Risk factors to develop multicentric lesions of the lower genital tract.
Gonzalez-Bosquet E, Mazarico E, Lorente N, Gomez-Roig MD
Eur J Gynaecol Oncol 2017;38(1):10-13. PMID: 29767857
Multicentric glioblastomas. Methods of diagnosis and treatment.
Schiefer W, Hasenbein B, Schmidt H
Acta Neurochir (Wien) 1978;42(1-2):89-95. doi: 10.1007/BF01406634. PMID: 211811

Prognosis

Pre-treatment MRI tumor features and post-treatment mammographic findings: may they contribute to refining the prediction of pathologic complete response in post-neoadjuvant breast cancer patients with radiologic complete response on MRI?
Thompson BM, Chala LF, Shimizu C, Mano MS, Filassi JR, Geyer FC, Torres US, de Mello GGN, da Costa Leite C
Eur Radiol 2022 Mar;32(3):1663-1675. Epub 2021 Oct 30 doi: 10.1007/s00330-021-08290-1. PMID: 34716780
Comparison of 3-Tesla to 1.5-Tesla Magnetic Resonance Enterography to assess multifocal and multicentric bowel endometriosis: Results in routine practice.
Allègre L, Aristizabal P, Nyangoh Timoh K, Thomassin-Naggara I, Kermarrec E, Bendifallah S, Darai E
Eur J Obstet Gynecol Reprod Biol 2018 Nov;230:172-177. Epub 2018 Sep 25 doi: 10.1016/j.ejogrb.2018.09.035. PMID: 30292947
Clinicopathological characteristics of invasive lobular carcinoma of the breast.
Hanagiri T, Nozoe T, Mizukami M, Ichiki Y, Sugaya M, Yasuda M, Takenoyama M, Sugio K, Yasumoto K
Asian J Surg 2009 Apr;32(2):76-80. doi: 10.1016/S1015-9584(09)60014-2. PMID: 19423452
Multiple enchondromas associated with spindle-cell hemangioendotheliomas. An overlooked variant of Maffucci's syndrome.
Fanburg JC, Meis-Kindblom JM, Rosenberg AE
Am J Surg Pathol 1995 Sep;19(9):1029-38. doi: 10.1097/00000478-199509000-00006. PMID: 7661276
Leiomyomatosis of the colon.
Freni SC, Keeman JN
Cancer 1977 Jan;39(1):263-6. doi: 10.1002/1097-0142(197701)39:1<263::aid-cncr2820390140>3.0.co;2-b. PMID: 832239

Clinical prediction guides

Pre-treatment MRI tumor features and post-treatment mammographic findings: may they contribute to refining the prediction of pathologic complete response in post-neoadjuvant breast cancer patients with radiologic complete response on MRI?
Thompson BM, Chala LF, Shimizu C, Mano MS, Filassi JR, Geyer FC, Torres US, de Mello GGN, da Costa Leite C
Eur Radiol 2022 Mar;32(3):1663-1675. Epub 2021 Oct 30 doi: 10.1007/s00330-021-08290-1. PMID: 34716780
Comparison of 3-Tesla to 1.5-Tesla Magnetic Resonance Enterography to assess multifocal and multicentric bowel endometriosis: Results in routine practice.
Allègre L, Aristizabal P, Nyangoh Timoh K, Thomassin-Naggara I, Kermarrec E, Bendifallah S, Darai E
Eur J Obstet Gynecol Reprod Biol 2018 Nov;230:172-177. Epub 2018 Sep 25 doi: 10.1016/j.ejogrb.2018.09.035. PMID: 30292947
Clinicopathological characteristics of invasive lobular carcinoma of the breast.
Hanagiri T, Nozoe T, Mizukami M, Ichiki Y, Sugaya M, Yasuda M, Takenoyama M, Sugio K, Yasumoto K
Asian J Surg 2009 Apr;32(2):76-80. doi: 10.1016/S1015-9584(09)60014-2. PMID: 19423452

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