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Diplegia

MedGen UID:
472941
•Concept ID:
C0221165
•
Disease or Syndrome
Synonym: Bilateral paralysis
SNOMED CT: Diplegia (6481005); Bilateral paralysis (6481005)

Definition

Paralysis affecting corresponding parts on both sides of the body. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVDiplegia

Professional guidelines

PubMed

Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
SELECTIVE DORSAL RHIZOTOMY IN CEREBRAL PALSY: SELECTION CRITERIA AND POSTOPERATIVE PHYSICAL THERAPY PROTOCOLS.
Nicolini-Panisson RD, Tedesco AP, Folle MR, Donadio MVF
Rev Paul Pediatr 2018 Jan-Mar;36(1):9. Epub 2018 Jan 15 doi: 10.1590/1984-0462/;2018;36;1;00005. PMID: 29412426Free PMC Article
The differential diagnosis of spastic diplegia.
Huntsman R, Lemire E, Norton J, Dzus A, Blakley P, Hasal S
Arch Dis Child 2015 May;100(5):500-4. Epub 2014 Nov 18 doi: 10.1136/archdischild-2014-307443. PMID: 25700542

Recent clinical studies

Etiology

Effect of simultaneous proprioceptive-visual feedback on gait of children with spastic diplegic cerebral palsy.
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Feeding children with cerebral palsy and swallowing difficulties.
Arvedson JC
Eur J Clin Nutr 2013 Dec;67 Suppl 2:S9-12. doi: 10.1038/ejcn.2013.224. PMID: 24301008
Idiopathic toe-walking.
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability.
Eliasson AC, Krumlinde-Sundholm L, Rösblad B, Beckung E, Arner M, Ohrvall AM, Rosenbaum P
Dev Med Child Neurol 2006 Jul;48(7):549-54. doi: 10.1017/S0012162206001162. PMID: 16780622
Cerebral palsy.
Srivastava VK, Laisram N, Srivastava RK
Indian Pediatr 1992 Aug;29(8):993-6. PMID: 1459721

Diagnosis

Phenotypic spectrum of inclusion body myositis.
Roy B, Dimachkie MM, Naddaf E
Clin Exp Rheumatol 2024 Feb;42(2):445-453. Epub 2024 Feb 28 doi: 10.55563/clinexprheumatol/fhrx3q. PMID: 38436356
X-linked mental deficiency.
des Portes V
Handb Clin Neurol 2013;111:297-306. doi: 10.1016/B978-0-444-52891-9.00035-X. PMID: 23622180
Sjogren-Larsson syndrome.
Dutra LA, Braga-Neto P, Pedroso JL, Povoas Barsottini OG
Adv Exp Med Biol 2012;724:344-50. doi: 10.1007/978-1-4614-0653-2_26. PMID: 22411255
Idiopathic toe-walking.
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Sjögren-Larsson syndrome.
Gordon N
Dev Med Child Neurol 2007 Feb;49(2):152-4. doi: 10.1111/j.1469-8749.2007.00152.x. PMID: 17254005

Therapy

Association of Guillain-Barré syndrome following COVID-19 vaccination.
Chowdhury S, Chowdhury S
Int J Immunopathol Pharmacol 2023 Jan-Dec;37:3946320231199349. doi: 10.1177/03946320231199349. PMID: 37681361Free PMC Article
The Influence of Hippotherapy on the Body Posture in a Sitting Position among Children with Cerebral Palsy.
Matusiak-Wieczorek E, Dziankowska-Zaborszczyk E, Synder M, Borowski A
Int J Environ Res Public Health 2020 Sep 19;17(18) doi: 10.3390/ijerph17186846. PMID: 32961681Free PMC Article
Effect of simultaneous proprioceptive-visual feedback on gait of children with spastic diplegic cerebral palsy.
Hussein ZA, Salem IA, Ali MS
J Musculoskelet Neuronal Interact 2019 Dec 1;19(4):500-506. PMID: 31789301Free PMC Article
Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Cerebral folate deficiency.
Hyland K, Shoffner J, Heales SJ
J Inherit Metab Dis 2010 Oct;33(5):563-70. Epub 2010 Jul 29 doi: 10.1007/s10545-010-9159-6. PMID: 20668945

Prognosis

Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Clinical, biochemical, and genetic aspects of Sjögren-Larsson syndrome.
Cho KH, Shim SH, Kim M
Clin Genet 2018 Apr;93(4):721-730. Epub 2017 Sep 17 doi: 10.1111/cge.13058. PMID: 28543186
Idiopathic toe-walking.
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
Neuroimaging in cerebral palsy.
Accardo J, Kammann H, Hoon AH Jr
J Pediatr 2004 Aug;145(2 Suppl):S19-27. doi: 10.1016/j.jpeds.2004.05.018. PMID: 15292883
Cerebral palsy.
Dabney KW, Lipton GE, Miller F
Curr Opin Pediatr 1997 Feb;9(1):81-8. doi: 10.1097/00008480-199702000-00017. PMID: 9088760

Clinical prediction guides

Botulinum Toxin in the Management of Children with Cerebral Palsy.
Multani I, Manji J, Hastings-Ison T, Khot A, Graham K
Paediatr Drugs 2019 Aug;21(4):261-281. doi: 10.1007/s40272-019-00344-8. PMID: 31257556Free PMC Article
Congenital and infantile myotonic dystrophy.
Echenne B, Bassez G
Handb Clin Neurol 2013;113:1387-93. doi: 10.1016/B978-0-444-59565-2.00009-5. PMID: 23622362
Idiopathic toe-walking.
Babb A, Carlson WO
S D Med 2008 Feb;61(2):53, 55-7. PMID: 18432151
The Manual Ability Classification System (MACS) for children with cerebral palsy: scale development and evidence of validity and reliability.
Eliasson AC, Krumlinde-Sundholm L, Rösblad B, Beckung E, Arner M, Ohrvall AM, Rosenbaum P
Dev Med Child Neurol 2006 Jul;48(7):549-54. doi: 10.1017/S0012162206001162. PMID: 16780622
Cerebral palsy.
Srivastava VK, Laisram N, Srivastava RK
Indian Pediatr 1992 Aug;29(8):993-6. PMID: 1459721

Recent systematic reviews

Effects of Hippotherapy on Postural Control in Children With Cerebral Palsy: A Systematic Review.
Peia F, Veiga NC, Gomes AP, Santos BND, Marques NMS, Glória IPDS, Goulardins JB
Pediatr Phys Ther 2023 Apr 1;35(2):202-210. Epub 2023 Mar 3 doi: 10.1097/PEP.0000000000000999. PMID: 36867588
Perinatal and long-term outcome of fetal intracranial hemorrhage: systematic review and meta-analysis.
Sileo FG, Zöllner J, D'Antonio F, Islam S, Papageorghiou AT, Khalil A
Ultrasound Obstet Gynecol 2022 May;59(5):585-595. doi: 10.1002/uog.24766. PMID: 34529308
Rehabilitation After Single-Event Multilevel Surgery for Children and Young Adults With Cerebral Palsy: A Systematic Review.
Guinet AL, Khouri N, Desailly E
Am J Phys Med Rehabil 2022 Apr 1;101(4):389-399. doi: 10.1097/PHM.0000000000001864. PMID: 34393188
A Case of Dentatotomy for Pain and Spasticity and Systematic Review.
Villegas-López FA, Armas-Salazar A, Beltrán JQ, Téllez-León N, Arellano-Alcántara A, Navarro-Olvera JL, Carrillo-Ruiz JD
Stereotact Funct Neurosurg 2021;99(6):521-525. Epub 2021 Jun 9 doi: 10.1159/000516423. PMID: 34107470
Classification of topographical pattern of spasticity in cerebral palsy: a registry perspective.
Reid SM, Carlin JB, Reddihough DS
Res Dev Disabil 2011 Nov-Dec;32(6):2909-15. Epub 2011 May 31 doi: 10.1016/j.ridd.2011.05.012. PMID: 21624819

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