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Metabolic bone disease of prematurity

MedGen UID:
473169
Concept ID:
C0456126
Disease or Syndrome
Synonyms: Neonatal Rickets; Neonatal rickets; Rickets of prematurity
SNOMED CT: Metabolic bone disease of prematurity (722928002); Neonatal rickets (276702002); Rickets of prematurity (722928002)

Definition

Rickets that usually affects premature infants. Factors that contribute to the development of neonatal rickets include calcium, phosphorus, or calciferol deficiency. It manifests with spontaneous fractures, respiratory distress, and growth developmental delays. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetabolic bone disease of prematurity

Professional guidelines

PubMed

Yan-Mei C, Xin-Zhu L, Rong Z, Xi-Hong L, Xiao-Mei T, Ping-Yang C, Zhi-Chun F; Nutritional Committee of Neonatology Branch of Chinese Medical Doctor Association; Neonatal Nutrition and Health Management Group, Professional Committee of Child Health, Chinese Medical Doctor Association; Editorial Committee of Chinese Journal of Contemporary Pediatrics.
Zhongguo Dang Dai Er Ke Za Zhi 2021 Aug 15;23(8):761-772. doi: 10.7499/j.issn.1008-8830.2105152. PMID: 34511163Free PMC Article
Chinoy A, Mughal MZ, Padidela R
Arch Dis Child Fetal Neonatal Ed 2019 Sep;104(5):F560-F566. Epub 2019 May 11 doi: 10.1136/archdischild-2018-316330. PMID: 31079069

Recent clinical studies

Etiology

Wang J, Zhao Q, Chen B, Sun J, Huang J, Meng J, Li S, Yan W, Ren C, Hao L
PLoS One 2022;17(6):e0269180. Epub 2022 Jun 13 doi: 10.1371/journal.pone.0269180. PMID: 35696368Free PMC Article
Kehinde F, Marinescu A, Turchi R
Curr Opin Pediatr 2021 Dec 1;33(6):676-683. doi: 10.1097/MOP.0000000000001060. PMID: 34734916
Avila-Alvarez A, Urisarri A, Fuentes-Carballal J, Mandiá N, Sucasas-Alonso A, Couce ML
Nutrients 2020 Dec 10;12(12) doi: 10.3390/nu12123786. PMID: 33321828Free PMC Article
Rayannavar A, Calabria AC
Semin Fetal Neonatal Med 2020 Feb;25(1):101086. Epub 2020 Jan 16 doi: 10.1016/j.siny.2020.101086. PMID: 32081592
Montaner Ramón A
Semin Fetal Neonatal Med 2020 Feb;25(1):101068. Epub 2019 Dec 2 doi: 10.1016/j.siny.2019.101068. PMID: 31862224

Diagnosis

Lee B, De Beritto T
Neoreviews 2022 May 1;23(5):e311-e318. doi: 10.1542/neo.23-5-e311. PMID: 35490181
Kehinde F, Marinescu A, Turchi R
Curr Opin Pediatr 2021 Dec 1;33(6):676-683. doi: 10.1097/MOP.0000000000001060. PMID: 34734916
Chinoy A, Mughal MZ, Padidela R
Acta Paediatr 2021 Jun;110(6):1855-1862. Epub 2020 Nov 20 doi: 10.1111/apa.15654. PMID: 33145793Free PMC Article
Rayannavar A, Calabria AC
Semin Fetal Neonatal Med 2020 Feb;25(1):101086. Epub 2020 Jan 16 doi: 10.1016/j.siny.2020.101086. PMID: 32081592
Chinoy A, Mughal MZ, Padidela R
Arch Dis Child Fetal Neonatal Ed 2019 Sep;104(5):F560-F566. Epub 2019 May 11 doi: 10.1136/archdischild-2018-316330. PMID: 31079069

Therapy

Krithika MV, Balakrishnan U, Amboiram P, Shaik MSJ, Chandrasekaran A, Ninan B
BMJ Open Qual 2022 Aug;11(Suppl 1) doi: 10.1136/bmjoq-2022-001841. PMID: 35995540Free PMC Article
Ukarapong S, Venkatarayappa SKB, Navarrete C, Berkovitz G
Early Hum Dev 2017 Sep;112:29-34. Epub 2017 Jul 3 doi: 10.1016/j.earlhumdev.2017.06.010. PMID: 28683339
Yeşiltepe Mutlu G, Kırmızıbekmez H, Ozsu E, Er I, Hatun S
J Clin Res Pediatr Endocrinol 2014;6(2):111-5. doi: 10.4274/Jcrpe.1282. PMID: 24932605Free PMC Article
Lothe A, Sinn J, Stone M
J Paediatr Child Health 2011 Aug;47(8):550-3. Epub 2011 Mar 10 doi: 10.1111/j.1440-1754.2011.02019.x. PMID: 21392146
Backström MC, Kuusela AL, Mäki R
Ann Med 1996 Aug;28(4):275-82. doi: 10.3109/07853899608999080. PMID: 8862679

Prognosis

Lü KL, Xie SS, Hu Q, Yang ZY, Fan QL, Liu E, Zhang YP
Bone 2023 Apr;169:116656. Epub 2022 Dec 29 doi: 10.1016/j.bone.2022.116656. PMID: 36586528
Perrone M, Casirati A, Stagi S, Amato O, Piemontese P, Liotto N, Orsi A, Menis C, Pesenti N, Tabasso C, Roggero P, Mosca F
Int J Mol Sci 2022 Sep 14;23(18) doi: 10.3390/ijms231810666. PMID: 36142579Free PMC Article
Yan-Mei C, Xin-Zhu L, Rong Z, Xi-Hong L, Xiao-Mei T, Ping-Yang C, Zhi-Chun F; Nutritional Committee of Neonatology Branch of Chinese Medical Doctor Association; Neonatal Nutrition and Health Management Group, Professional Committee of Child Health, Chinese Medical Doctor Association; Editorial Committee of Chinese Journal of Contemporary Pediatrics.
Zhongguo Dang Dai Er Ke Za Zhi 2021 Aug 15;23(8):761-772. doi: 10.7499/j.issn.1008-8830.2105152. PMID: 34511163Free PMC Article
Czech-Kowalska J, Czekuc-Kryskiewicz E, Pludowski P, Zaniuk K, Jaworski M, Łuba A, Grzybowska K, Piłat K, Dobrzanska A
PLoS One 2016;11(11):e0165727. Epub 2016 Nov 2 doi: 10.1371/journal.pone.0165727. PMID: 27806112Free PMC Article
Yeşiltepe Mutlu G, Kırmızıbekmez H, Ozsu E, Er I, Hatun S
J Clin Res Pediatr Endocrinol 2014;6(2):111-5. doi: 10.4274/Jcrpe.1282. PMID: 24932605Free PMC Article

Clinical prediction guides

Lü KL, Xie SS, Hu Q, Yang ZY, Fan QL, Liu E, Zhang YP
Bone 2023 Apr;169:116656. Epub 2022 Dec 29 doi: 10.1016/j.bone.2022.116656. PMID: 36586528
Avila-Alvarez A, Urisarri A, Fuentes-Carballal J, Mandiá N, Sucasas-Alonso A, Couce ML
Nutrients 2020 Dec 10;12(12) doi: 10.3390/nu12123786. PMID: 33321828Free PMC Article
Chin LK, Doan J, Teoh YS, Stewart A, Forrest P, Simm PJ
J Paediatr Child Health 2018 Jun;54(6):665-670. Epub 2018 Jan 2 doi: 10.1111/jpc.13813. PMID: 29292538
Ukarapong S, Venkatarayappa SKB, Navarrete C, Berkovitz G
Early Hum Dev 2017 Sep;112:29-34. Epub 2017 Jul 3 doi: 10.1016/j.earlhumdev.2017.06.010. PMID: 28683339
Czech-Kowalska J, Czekuc-Kryskiewicz E, Pludowski P, Zaniuk K, Jaworski M, Łuba A, Grzybowska K, Piłat K, Dobrzanska A
PLoS One 2016;11(11):e0165727. Epub 2016 Nov 2 doi: 10.1371/journal.pone.0165727. PMID: 27806112Free PMC Article

Recent systematic reviews

Tong L, Gopal-Kothandapani JS, Offiah AC
Pediatr Radiol 2018 Oct;48(11):1537-1549. Epub 2018 Jun 16 doi: 10.1007/s00247-018-4161-5. PMID: 29907939Free PMC Article

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