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Gallbladder Hepatoid Adenocarcinoma

MedGen UID:
473518
Concept ID:
C2030691
Neoplastic Process

Definition

A rare variant of gallbladder adenocarcinoma. It is characterized by the presence of a malignant glandular epithelial infiltrate that resembles hepatocellular carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Hepatoid Adenocarcinoma

Recent clinical studies

Etiology

Nasir A, Lehrke HD, Mounajjed T, Said S, Zhang L, Yasir S, Shah SS, Chandan VS, Smyrk TC, Moreira RK, Boland Froemming JM, Herrera Hernandez LP, Wu TT, Graham RP
Am J Clin Pathol 2019 Jul 5;152(2):190-199. doi: 10.1093/ajcp/aqz032. PMID: 31107526
Nakashima H, Nagafuchi K, Satoh H, Takeda K, Yamasaki T, Yonemasu H, Kishikawa H
J Hepatobiliary Pancreat Surg 2000;7(2):226-30. doi: 10.1007/s005340050181. PMID: 10982619

Diagnosis

Caruana G, Cachia R, Micallef S, Sammut M, Psaila J
BMJ Case Rep 2024 Apr 9;17(4) doi: 10.1136/bcr-2022-253747. PMID: 38594200Free PMC Article
Yoshioka S, Ishida M, Okano K, Sandoh K, Ebisu Y, Miyasaka C, Yamamoto T, Ryota H, Satoi S, Tsuta K
Diagn Cytopathol 2018 Aug;46(8):711-715. Epub 2018 Apr 10 doi: 10.1002/dc.23935. PMID: 29637715
Ellouze S, Slim C, Ahmad G, Naourez G, Ali A, Héla M, Mariem K, Mohamed BA, Tahia B
World J Surg Oncol 2011 Sep 13;9:103. doi: 10.1186/1477-7819-9-103. PMID: 21914163Free PMC Article
Sakamoto K, Monobe Y, Kouno M, Moriya T, Sasano H
Pathol Int 2004 Jan;54(1):52-6. doi: 10.1111/j.1440-1827.2004.01578.x. PMID: 14674996
Nakashima H, Nagafuchi K, Satoh H, Takeda K, Yamasaki T, Yonemasu H, Kishikawa H
J Hepatobiliary Pancreat Surg 2000;7(2):226-30. doi: 10.1007/s005340050181. PMID: 10982619

Therapy

Metzgeroth G, Ströbel P, Baumbusch T, Reiter A, Hastka J
Onkologie 2010;33(5):263-9. Epub 2010 Apr 13 doi: 10.1159/000305717. PMID: 20502062

Prognosis

Yoshioka S, Ishida M, Okano K, Sandoh K, Ebisu Y, Miyasaka C, Yamamoto T, Ryota H, Satoi S, Tsuta K
Diagn Cytopathol 2018 Aug;46(8):711-715. Epub 2018 Apr 10 doi: 10.1002/dc.23935. PMID: 29637715
Karayiannakis AJ, Kakolyris S, Giatromanolaki A, Courcoutsakis N, Bolanaki H, Chelis L, Sivridis E, Simopoulos C
J Gastrointest Cancer 2012 Sep;43 Suppl 1:S139-44. doi: 10.1007/s12029-011-9326-5. PMID: 21935757
Metzgeroth G, Ströbel P, Baumbusch T, Reiter A, Hastka J
Onkologie 2010;33(5):263-9. Epub 2010 Apr 13 doi: 10.1159/000305717. PMID: 20502062
Sakamoto K, Monobe Y, Kouno M, Moriya T, Sasano H
Pathol Int 2004 Jan;54(1):52-6. doi: 10.1111/j.1440-1827.2004.01578.x. PMID: 14674996
Nakashima H, Nagafuchi K, Satoh H, Takeda K, Yamasaki T, Yonemasu H, Kishikawa H
J Hepatobiliary Pancreat Surg 2000;7(2):226-30. doi: 10.1007/s005340050181. PMID: 10982619

Clinical prediction guides

Chun J, Moore M, Kelly P, Kanzawa M, Itoh T, Hong SM, Zen Y
Hum Pathol 2024 Feb;144:46-52. Epub 2024 Jan 30 doi: 10.1016/j.humpath.2024.01.011. PMID: 38301963
Koyama K, Maeda D, Tamura D, Narita C, Kudo-Asabe Y, Sato T, Yamamoto Y, Sageshima M, Nanjo H, Goto A
Hum Pathol 2017 Dec;70:27-34. Epub 2017 Sep 29 doi: 10.1016/j.humpath.2017.09.009. PMID: 28970139
Arnould L, Drouot F, Fargeot P, Bernard A, Foucher P, Collin F, Petrella T
Am J Surg Pathol 1997 Sep;21(9):1113-8. doi: 10.1097/00000478-199709000-00018. PMID: 9298890

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