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Severe Cardiac Valve Stenosis

MedGen UID:
473891
•Concept ID:
C3272258
•
Finding

Definition

The cardiac valve orifice is abnormally narrow, to a severe degree. (ACC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSevere Cardiac Valve Stenosis

Professional guidelines

PubMed

ESC/EACTS vs. ACC/AHA guidelines for the management of severe aortic stenosis.
Lee G, Chikwe J, Milojevic M, Wijeysundera HC, Biondi-Zoccai G, Flather M, Gaudino MFL, Fremes SE, Tam DY
Eur Heart J 2023 Mar 7;44(10):796-812. doi: 10.1093/eurheartj/ehac803. PMID: 36632841
Transcatheter Treatment of Valvular Heart Disease: A Review.
Davidson LJ, Davidson CJ
JAMA 2021 Jun 22;325(24):2480-2494. doi: 10.1001/jama.2021.2133. PMID: 34156404
Management of Patients With Aortic Valve Stenosis.
Kanwar A, Thaden JJ, Nkomo VT
Mayo Clin Proc 2018 Apr;93(4):488-508. doi: 10.1016/j.mayocp.2018.01.020. PMID: 29622096

Recent clinical studies

Etiology

TAVI in 2022: Remaining issues and future direction.
Webb JG, Blanke P, Meier D, Sathananthan J, Lauck S, Chatfield AG, Jelisejevas J, Wood DA, Akodad M
Arch Cardiovasc Dis 2022 Apr;115(4):235-242. Epub 2022 Apr 20 doi: 10.1016/j.acvd.2022.04.001. PMID: 35527211
Paravalvular Leak.
Qamar F, Attar RH, Nabi F
Methodist Debakey Cardiovasc J 2022;18(1):7-9. Epub 2022 Apr 1 doi: 10.14797/mdcvj.1096. PMID: 35432730Free PMC Article
Transcatheter Treatment of Valvular Heart Disease: A Review.
Davidson LJ, Davidson CJ
JAMA 2021 Jun 22;325(24):2480-2494. doi: 10.1001/jama.2021.2133. PMID: 34156404
Sutureless aortic valve prostheses.
Bilkhu R, Borger MA, Briffa NP, Jahangiri M
Heart 2019 Mar;105(Suppl 2):s16-s20. doi: 10.1136/heartjnl-2018-313513. PMID: 30846520
Calcific aortic stenosis.
Lindman BR, Clavel MA, Mathieu P, Iung B, Lancellotti P, Otto CM, Pibarot P
Nat Rev Dis Primers 2016 Mar 3;2:16006. doi: 10.1038/nrdp.2016.6. PMID: 27188578Free PMC Article

Diagnosis

Management of Asymptomatic Severe Aortic Stenosis: Evolving Concepts in Timing of Valve Replacement.
Lindman BR, Dweck MR, Lancellotti P, Généreux P, Piérard LA, O'Gara PT, Bonow RO
JACC Cardiovasc Imaging 2020 Feb;13(2 Pt 1):481-493. Epub 2019 Jun 12 doi: 10.1016/j.jcmg.2019.01.036. PMID: 31202751
Rheumatic Mitral Valve Stenosis: Diagnosis and Treatment Options.
Wunderlich NC, Dalvi B, Ho SY, Küx H, Siegel RJ
Curr Cardiol Rep 2019 Feb 28;21(3):14. doi: 10.1007/s11886-019-1099-7. PMID: 30815750
Calcific aortic stenosis.
Lindman BR, Clavel MA, Mathieu P, Iung B, Lancellotti P, Otto CM, Pibarot P
Nat Rev Dis Primers 2016 Mar 3;2:16006. doi: 10.1038/nrdp.2016.6. PMID: 27188578Free PMC Article
Bicuspid aortic valve disease.
Siu SC, Silversides CK
J Am Coll Cardiol 2010 Jun 22;55(25):2789-800. doi: 10.1016/j.jacc.2009.12.068. PMID: 20579534
Aortic stenosis.
Singh GK
Indian J Pediatr 2002 Apr;69(4):351-8. doi: 10.1007/BF02723222. PMID: 12019557

Therapy

TAVI in 2022: Remaining issues and future direction.
Webb JG, Blanke P, Meier D, Sathananthan J, Lauck S, Chatfield AG, Jelisejevas J, Wood DA, Akodad M
Arch Cardiovasc Dis 2022 Apr;115(4):235-242. Epub 2022 Apr 20 doi: 10.1016/j.acvd.2022.04.001. PMID: 35527211
Paravalvular Leak.
Qamar F, Attar RH, Nabi F
Methodist Debakey Cardiovasc J 2022;18(1):7-9. Epub 2022 Apr 1 doi: 10.14797/mdcvj.1096. PMID: 35432730Free PMC Article
A Review of the Partner Trials.
Markham R, Sharma R
Interv Cardiol Clin 2020 Oct;9(4):461-467. doi: 10.1016/j.iccl.2020.07.002. PMID: 32921370
Calcific aortic stenosis.
Lindman BR, Clavel MA, Mathieu P, Iung B, Lancellotti P, Otto CM, Pibarot P
Nat Rev Dis Primers 2016 Mar 3;2:16006. doi: 10.1038/nrdp.2016.6. PMID: 27188578Free PMC Article
Transcatheter versus surgical aortic-valve replacement in high-risk patients.
Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ; PARTNER Trial Investigators
N Engl J Med 2011 Jun 9;364(23):2187-98. Epub 2011 Jun 5 doi: 10.1056/NEJMoa1103510. PMID: 21639811

Prognosis

What do we know about carcinoid heart disease in the present era?
Pęczkowska M, Konsek-Komorowska SJ, Kolasińska-Ćwikła AD, Konka M, Michałowska I, Ćwikła JB
Kardiol Pol 2022;80(10):990-1001. Epub 2022 Sep 22 doi: 10.33963/KP.a2022.0222. PMID: 36136036
Transcatheter valve interventions in heart failure: new answers to old questions.
Tadic M, Cuspidi C
Heart Fail Rev 2018 Nov;23(6):859-870. doi: 10.1007/s10741-018-9701-4. PMID: 29654449
5-year outcomes of transcatheter aortic valve replacement or surgical aortic valve replacement for high surgical risk patients with aortic stenosis (PARTNER 1): a randomised controlled trial.
Mack MJ, Leon MB, Smith CR, Miller DC, Moses JW, Tuzcu EM, Webb JG, Douglas PS, Anderson WN, Blackstone EH, Kodali SK, Makkar RR, Fontana GP, Kapadia S, Bavaria J, Hahn RT, Thourani VH, Babaliaros V, Pichard A, Herrmann HC, Brown DL, Williams M, Akin J, Davidson MJ, Svensson LG; PARTNER 1 trial investigators
Lancet 2015 Jun 20;385(9986):2477-84. Epub 2015 Mar 15 doi: 10.1016/S0140-6736(15)60308-7. PMID: 25788234
Carcinoid heart disease.
Palaniswamy C, Frishman WH, Aronow WS
Cardiol Rev 2012 Jul-Aug;20(4):167-76. doi: 10.1097/CRD.0b013e31824c866e. PMID: 22314145
Bicuspid aortic valve disease.
Siu SC, Silversides CK
J Am Coll Cardiol 2010 Jun 22;55(25):2789-800. doi: 10.1016/j.jacc.2009.12.068. PMID: 20579534

Clinical prediction guides

Transcatheter Treatment of Valvular Heart Disease: A Review.
Davidson LJ, Davidson CJ
JAMA 2021 Jun 22;325(24):2480-2494. doi: 10.1001/jama.2021.2133. PMID: 34156404
Accessory mitral valve tissue: anatomical and clinical perspectives.
Yetkin E, Cuglan B, Turhan H, Yalta K
Cardiovasc Pathol 2021 Jan-Feb;50:107277. Epub 2020 Aug 31 doi: 10.1016/j.carpath.2020.107277. PMID: 32882373
Coronary Access After TAVR.
Ochiai T, Chakravarty T, Yoon SH, Kaewkes D, Flint N, Patel V, Mahani S, Tiwana R, Sekhon N, Nakamura M, Cheng W, Makkar R
JACC Cardiovasc Interv 2020 Mar 23;13(6):693-705. doi: 10.1016/j.jcin.2020.01.216. PMID: 32192689
Cardiac Imaging for Assessing Low-Gradient Severe Aortic Stenosis.
Clavel MA, Burwash IG, Pibarot P
JACC Cardiovasc Imaging 2017 Feb;10(2):185-202. doi: 10.1016/j.jcmg.2017.01.002. PMID: 28183438
Update on percutaneous mitral commissurotomy.
Nunes MC, Nascimento BR, Lodi-Junqueira L, Tan TC, Athayde GR, Hung J
Heart 2016 Apr;102(7):500-7. Epub 2016 Jan 7 doi: 10.1136/heartjnl-2015-308091. PMID: 26743926

Recent systematic reviews

Transcatheter aortic valve implantation versus surgical aortic valve replacement in patients with severe aortic stenosis: a systematic review and meta-analysis.
Swift SL, Puehler T, Misso K, Lang SH, Forbes C, Kleijnen J, Danner M, Kuhn C, Haneya A, Seoudy H, Cremer J, Frey N, Lutter G, Wolff R, Scheibler F, Wehkamp K, Frank D
BMJ Open 2021 Dec 6;11(12):e054222. doi: 10.1136/bmjopen-2021-054222. PMID: 34873012Free PMC Article
Dual Antiplatelet Therapy After Percutaneous Coronary Intervention and Drug-Eluting Stents: A Systematic Review and Network Meta-Analysis.
Khan SU, Singh M, Valavoor S, Khan MU, Lone AN, Khan MZ, Khan MS, Mani P, Kapadia SR, Michos ED, Stone GW, Kalra A, Bhatt DL
Circulation 2020 Oct 13;142(15):1425-1436. Epub 2020 Aug 3 doi: 10.1161/CIRCULATIONAHA.120.046308. PMID: 32795096Free PMC Article
Transthyretin Cardiac Amyloidosis and Aortic Stenosis: Connection and Therapeutic Implications.
Penalver J, Ambrosino M, Jeon HD, Agrawal A, Kanjanahattakij N, Pitteloud M, Stempel J, Amanullah A
Curr Cardiol Rev 2020;16(3):221-230. doi: 10.2174/1573403X15666190722154152. PMID: 31544701Free PMC Article
Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis.
Siontis GCM, Overtchouk P, Cahill TJ, Modine T, Prendergast B, Praz F, Pilgrim T, Petrinic T, Nikolakopoulou A, Salanti G, Søndergaard L, Verma S, Jüni P, Windecker S
Eur Heart J 2019 Oct 7;40(38):3143-3153. doi: 10.1093/eurheartj/ehz275. PMID: 31329852
Aortic stenosis and non-cardiac surgery: A systematic review and meta-analysis.
Kwok CS, Bagur R, Rashid M, Lavi R, Cibelli M, de Belder MA, Moat N, Hildick-Smith D, Ludman P, Mamas MA
Int J Cardiol 2017 Aug 1;240:145-153. Epub 2017 Apr 12 doi: 10.1016/j.ijcard.2017.04.037. PMID: 28431770

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