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Ampulla of Vater Invasive Papillary Adenocarcinoma

MedGen UID:
474098
•Concept ID:
C3272465
•
Neoplastic Process

Definition

An invasive adenocarcinoma that arises from an exophytic papillary neoplasm of the ampulla of Vater. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpulla of Vater Invasive Papillary Adenocarcinoma

Professional guidelines

PubMed

Proposed indications for limited resection of early ampulla of Vater carcinoma: clinico-histopathological criteria to confirm cure.
Aiura K, Hibi T, Fujisaki H, Kitago M, Tanabe M, Kawachi S, Itano O, Shinoda M, Yagi H, Masugi Y, Sakamoto M, Kitagawa Y
J Hepatobiliary Pancreat Sci 2012 Nov;19(6):707-16. doi: 10.1007/s00534-011-0492-4. PMID: 22203456Free PMC Article

Recent clinical studies

Etiology

Prediction of tumor recurrence and poor survival of ampullary adenocarcinoma using preoperative clinical and CT findings.
Yoen H, Kim JH, Hur BY, Ahn SJ, Jeon SK, Choi SY, Lee KB, Han JK
Eur Radiol 2021 Apr;31(4):2433-2443. Epub 2020 Sep 30 doi: 10.1007/s00330-020-07316-4. PMID: 33000305
Prognostic Impact of Intra-Ampullary Papillary-Tubular Neoplasm versus Flat Dysplasia as Precursor Lesions of Ampullary Adenocarcinoma.
Han S, Jang KT, Choi DW, Choi SH, Heo JS, Han IW, Park D, Ryu Y
Dig Surg 2020;37(6):505-514. Epub 2020 Oct 20 doi: 10.1159/000510961. PMID: 33080609
Tumors of the ampulla of vater: histopathologic classification and predictors of survival.
Carter JT, Grenert JP, Rubenstein L, Stewart L, Way LW
J Am Coll Surg 2008 Aug;207(2):210-8. Epub 2008 May 5 doi: 10.1016/j.jamcollsurg.2008.01.028. PMID: 18656049
Carcinoma of the ampulla of Vater.
Yamaguchi K, Nagai E, Ueki T, Nishihara K, Tamaka M
Aust N Z J Surg 1993 Apr;63(4):256-62. doi: 10.1111/j.1445-2197.1993.tb00378.x. PMID: 7906119
The histopathology and staging of carcinoma of the ampulla of Vater.
Talbot IC, Neoptolemos JP, Shaw DE, Carr-Locke D
Histopathology 1988 Feb;12(2):155-65. doi: 10.1111/j.1365-2559.1988.tb01926.x. PMID: 3366434

Diagnosis

Current status of and future issues related to endoscopic papillectomy.
Kawashima H, Ishikawa T, Yamao K, Mizutani Y, Iida T, Uetsuki K, Yamamura T, Furukawa K, Nakamura M
Nagoya J Med Sci 2023 Nov;85(4):648-658. doi: 10.18999/nagjms.85.4.648. PMID: 38155621Free PMC Article
Rare cause of obstructive icterus in a young patient.
Kundratová M
Vnitr Lek 2022 Winter;68(E-8):18-22. doi: 10.36290/vnl.2022.117. PMID: 36575062
Endoscopic ampullectomy for non-invasive ampullary lesions: a single-center 10-year retrospective cohort study.
Lee R, Huelsen A, Gupta S, Hourigan LF
Surg Endosc 2021 Feb;35(2):684-692. Epub 2020 Mar 25 doi: 10.1007/s00464-020-07433-7. PMID: 32215745
Tumoral Versus Flat Intraepithelial Neoplasia of Pancreatobiliary Tract, Gallbladder, and Ampulla of Vater.
Jang KT, Ahn S
Arch Pathol Lab Med 2016 May;140(5):429-36. doi: 10.5858/arpa.2015-0319-RA. PMID: 27128300
An introduction to mucin-producing tumors of the pancreas: why they deserve more attention.
Takada T, Yasuda H, Amano H, Yoshida M, Hijikata H, Takada K
Hepatogastroenterology 1998 Nov-Dec;45(24):1967-72. PMID: 9951849

Therapy

Endoscopic ampullectomy for non-invasive ampullary lesions: a single-center 10-year retrospective cohort study.
Lee R, Huelsen A, Gupta S, Hourigan LF
Surg Endosc 2021 Feb;35(2):684-692. Epub 2020 Mar 25 doi: 10.1007/s00464-020-07433-7. PMID: 32215745
Endoscopic papillectomy for early ampullary tumors: long-term results from a large multicenter prospective study.
Napoleon B, Gincul R, Ponchon T, Berthiller J, Escourrou J, Canard JM, Boyer J, Barthet M, Ponsot P, Laugier R, Helbert T, Coumaros D, Scoazec JY, Mion F, Saurin JC; Sociéte Française d’Endoscopie Digestive (SFED, French Society of Digestive Endoscopy)
Endoscopy 2014 Feb;46(2):127-34. Epub 2014 Jan 29 doi: 10.1055/s-0034-1364875. PMID: 24477368
Endoscopic resection of ampullary neoplasms: a single-center experience.
Jung MK, Cho CM, Park SY, Jeon SW, Tak WY, Kweon YO, Kim SK, Choi YH
Surg Endosc 2009 Nov;23(11):2568-74. Epub 2009 Apr 10 doi: 10.1007/s00464-009-0464-9. PMID: 19360365

Prognosis

Prediction of tumor recurrence and poor survival of ampullary adenocarcinoma using preoperative clinical and CT findings.
Yoen H, Kim JH, Hur BY, Ahn SJ, Jeon SK, Choi SY, Lee KB, Han JK
Eur Radiol 2021 Apr;31(4):2433-2443. Epub 2020 Sep 30 doi: 10.1007/s00330-020-07316-4. PMID: 33000305
Prognostic Impact of Intra-Ampullary Papillary-Tubular Neoplasm versus Flat Dysplasia as Precursor Lesions of Ampullary Adenocarcinoma.
Han S, Jang KT, Choi DW, Choi SH, Heo JS, Han IW, Park D, Ryu Y
Dig Surg 2020;37(6):505-514. Epub 2020 Oct 20 doi: 10.1159/000510961. PMID: 33080609
Tumors of the ampulla of vater: histopathologic classification and predictors of survival.
Carter JT, Grenert JP, Rubenstein L, Stewart L, Way LW
J Am Coll Surg 2008 Aug;207(2):210-8. Epub 2008 May 5 doi: 10.1016/j.jamcollsurg.2008.01.028. PMID: 18656049
Carcinoma of the ampulla of Vater.
Yamaguchi K, Nagai E, Ueki T, Nishihara K, Tamaka M
Aust N Z J Surg 1993 Apr;63(4):256-62. doi: 10.1111/j.1445-2197.1993.tb00378.x. PMID: 7906119
The histopathology and staging of carcinoma of the ampulla of Vater.
Talbot IC, Neoptolemos JP, Shaw DE, Carr-Locke D
Histopathology 1988 Feb;12(2):155-65. doi: 10.1111/j.1365-2559.1988.tb01926.x. PMID: 3366434

Clinical prediction guides

CASE STUDY: MAJOR DUODENAL PAPILLA CANCER COMPLICATED BY ACUTE PARACANCROTIC NECROTIZING PANCREATITIS.
Dronov OI, Kovalska IO, Horlach AI, Levchenko LV, Shchyhel IA
Wiad Lek 2022;75(4 pt 2):1039-1042. doi: 10.36740/WLek202204222. PMID: 35633340
Prediction of tumor recurrence and poor survival of ampullary adenocarcinoma using preoperative clinical and CT findings.
Yoen H, Kim JH, Hur BY, Ahn SJ, Jeon SK, Choi SY, Lee KB, Han JK
Eur Radiol 2021 Apr;31(4):2433-2443. Epub 2020 Sep 30 doi: 10.1007/s00330-020-07316-4. PMID: 33000305
Prognostic Impact of Intra-Ampullary Papillary-Tubular Neoplasm versus Flat Dysplasia as Precursor Lesions of Ampullary Adenocarcinoma.
Han S, Jang KT, Choi DW, Choi SH, Heo JS, Han IW, Park D, Ryu Y
Dig Surg 2020;37(6):505-514. Epub 2020 Oct 20 doi: 10.1159/000510961. PMID: 33080609
Tumors of the ampulla of vater: histopathologic classification and predictors of survival.
Carter JT, Grenert JP, Rubenstein L, Stewart L, Way LW
J Am Coll Surg 2008 Aug;207(2):210-8. Epub 2008 May 5 doi: 10.1016/j.jamcollsurg.2008.01.028. PMID: 18656049
The histopathology and staging of carcinoma of the ampulla of Vater.
Talbot IC, Neoptolemos JP, Shaw DE, Carr-Locke D
Histopathology 1988 Feb;12(2):155-65. doi: 10.1111/j.1365-2559.1988.tb01926.x. PMID: 3366434

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