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Localized Hemorrhagic and Ulcerated Lesion

MedGen UID:
474264
•Concept ID:
C3272631
•
Finding

Definition

A finding indicating the presence of a focal ulcerated lesion that is associated with hemorrhage. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocalized Hemorrhagic and Ulcerated Lesion

Professional guidelines

PubMed

Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium.
Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Genetic and developmental disorders of the oral mucosa: Epidemiology; molecular mechanisms; diagnostic criteria; management.
Pinna R, Cocco F, Campus G, Conti G, Milia E, Sardella A, Cagetti MG
Periodontol 2000 2019 Jun;80(1):12-27. doi: 10.1111/prd.12261. PMID: 31090139
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048

Recent clinical studies

Etiology

Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium.
Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Dermatofibrosarcoma Protuberans in Children.
Sleiwah A, Wright TC, Chapman T, Dangoor A, Maggiani F, Clancy R
Curr Treat Options Oncol 2022 Jun;23(6):843-854. Epub 2022 Apr 8 doi: 10.1007/s11864-022-00979-9. PMID: 35394606
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
Cunningham TJ, Tabacchi M, Eliane JP, Tuchayi SM, Manivasagam S, Mirzaalian H, Turkoz A, Kopan R, Schaffer A, Saavedra AP, Wallendorf M, Cornelius LA, Demehri S
J Clin Invest 2017 Jan 3;127(1):106-116. Epub 2016 Nov 21 doi: 10.1172/JCI89820. PMID: 27869649Free PMC Article
Granulomatous vasculitis.
Marzano AV, Balice Y, Tavecchio S, Desimine C, Colombo A, Berti E
G Ital Dermatol Venereol 2015 Apr;150(2):193-202. Epub 2015 Mar 19 PMID: 25791629
Peripheral arterial disease.
Ouriel K
Lancet 2001 Oct 13;358(9289):1257-64. doi: 10.1016/S0140-6736(01)06351-6. PMID: 11675083

Diagnosis

Dermatofibrosarcoma Protuberans in Children.
Sleiwah A, Wright TC, Chapman T, Dangoor A, Maggiani F, Clancy R
Curr Treat Options Oncol 2022 Jun;23(6):843-854. Epub 2022 Apr 8 doi: 10.1007/s11864-022-00979-9. PMID: 35394606
Oral lichen planus - Differential diagnoses, serum autoantibodies, hematinic deficiencies, and management.
Chiang CP, Yu-Fong Chang J, Wang YP, Wu YH, Lu SY, Sun A
J Formos Med Assoc 2018 Sep;117(9):756-765. Epub 2018 Feb 19 doi: 10.1016/j.jfma.2018.01.021. PMID: 29472048
Granulomatous vasculitis.
Marzano AV, Balice Y, Tavecchio S, Desimine C, Colombo A, Berti E
G Ital Dermatol Venereol 2015 Apr;150(2):193-202. Epub 2015 Mar 19 PMID: 25791629
Dieulafoy's lesion: an overview.
Joarder AI, Faruque MS, Nur-E-Elahi M, Jahan I, Siddiqui O, Imdad S, Islam MS, Ahmed HS, Haque MA
Mymensingh Med J 2014 Jan;23(1):186-94. PMID: 24584397
Ischemic colitis.
Montessori G, Liepa EV
Can Med Assoc J 1970 Feb 28;102(4):377-80. PMID: 5308923Free PMC Article

Therapy

Management of pouch neoplasia: consensus guidelines from the International Ileal Pouch Consortium.
Kiran RP, Kochhar GS, Kariv R, Rex DK, Sugita A, Rubin DT, Navaneethan U, Hull TL, Ko HM, Liu X, Kachnic LA, Strong S, Iacucci M, Bemelman W, Fleshner P, Safyan RA, Kotze PG, D'Hoore A, Faiz O, Lo S, Ashburn JH, Spinelli A, Bernstein CN, Kane SV, Cross RK, Schairer J, McCormick JT, Farraye FA, Chang S, Scherl EJ, Schwartz DA, Bruining DH, Philpott J, Bentley-Hibbert S, Tarabar D, El-Hachem S, Sandborn WJ, Silverberg MS, Pardi DS, Church JM, Shen B
Lancet Gastroenterol Hepatol 2022 Sep;7(9):871-893. Epub 2022 Jul 5 doi: 10.1016/S2468-1253(22)00039-5. PMID: 35798022
Randomized trial of calcipotriol combined with 5-fluorouracil for skin cancer precursor immunotherapy.
Cunningham TJ, Tabacchi M, Eliane JP, Tuchayi SM, Manivasagam S, Mirzaalian H, Turkoz A, Kopan R, Schaffer A, Saavedra AP, Wallendorf M, Cornelius LA, Demehri S
J Clin Invest 2017 Jan 3;127(1):106-116. Epub 2016 Nov 21 doi: 10.1172/JCI89820. PMID: 27869649Free PMC Article
A review of stress-related mucosal disease.
Monnig AA, Prittie JE
J Vet Emerg Crit Care (San Antonio) 2011 Oct;21(5):484-95. doi: 10.1111/j.1476-4431.2011.00680.x. PMID: 22316196
Peripheral arterial disease.
Ouriel K
Lancet 2001 Oct 13;358(9289):1257-64. doi: 10.1016/S0140-6736(01)06351-6. PMID: 11675083
Screening of colorectal cancer.
Bader JP
Dig Dis Sci 1986 Sep;31(9 Suppl):43S-56S. doi: 10.1007/BF01295989. PMID: 3089745

Prognosis

Dermatofibrosarcoma Protuberans in Children.
Sleiwah A, Wright TC, Chapman T, Dangoor A, Maggiani F, Clancy R
Curr Treat Options Oncol 2022 Jun;23(6):843-854. Epub 2022 Apr 8 doi: 10.1007/s11864-022-00979-9. PMID: 35394606
Granulomatous vasculitis.
Marzano AV, Balice Y, Tavecchio S, Desimine C, Colombo A, Berti E
G Ital Dermatol Venereol 2015 Apr;150(2):193-202. Epub 2015 Mar 19 PMID: 25791629
Dieulafoy's lesion: an overview.
Joarder AI, Faruque MS, Nur-E-Elahi M, Jahan I, Siddiqui O, Imdad S, Islam MS, Ahmed HS, Haque MA
Mymensingh Med J 2014 Jan;23(1):186-94. PMID: 24584397
The clinical spectrum of lipodermatosclerosis.
Kirsner RS, Pardes JB, Eaglstein WH, Falanga V
J Am Acad Dermatol 1993 Apr;28(4):623-7. doi: 10.1016/0190-9622(93)70085-8. PMID: 8463465
Screening of colorectal cancer.
Bader JP
Dig Dis Sci 1986 Sep;31(9 Suppl):43S-56S. doi: 10.1007/BF01295989. PMID: 3089745

Clinical prediction guides

Cutaneous Manifestations of Medium- and Large-Vessel Vasculitis.
Chasset F, Francès C
Clin Rev Allergy Immunol 2017 Dec;53(3):452-468. doi: 10.1007/s12016-017-8612-9. PMID: 28547523
Quantitative measurements in capsule endoscopy.
Keuchel M, Kurniawan N, Baltes P, Bandorski D, Koulaouzidis A
Comput Biol Med 2015 Oct 1;65:333-47. Epub 2015 Jul 29 doi: 10.1016/j.compbiomed.2015.07.016. PMID: 26299419
Clinical, serological and genetic predictors of inflammatory bowel disease course.
Beaugerie L, Sokol H
World J Gastroenterol 2012 Aug 7;18(29):3806-13. doi: 10.3748/wjg.v18.i29.3806. PMID: 22876031Free PMC Article
Neutrophilic dermatoses: a review of current treatment options.
Cohen PR
Am J Clin Dermatol 2009;10(5):301-12. doi: 10.2165/11310730-000000000-00000. PMID: 19658442
Idiopathic atrophie blanche.
Amato L, Chiarini C, Berti S, Massi D, Fabbri P
Skinmed 2006 May-Jun;5(3):151-4. doi: 10.1111/j.1540-9740.2006.04541.x. PMID: 16687988

Recent systematic reviews

A Systematic Review Comparing Outcomes of Local Flap Options for Reconstruction of Pressure Sores.
Vathulya M, Praveen AJ, Barik S, Jagtap MP, Kandwal P
Ann Plast Surg 2022 Jan 1;88(1):105-113. doi: 10.1097/SAP.0000000000002941. PMID: 34225313
Ulcus vulvae acutum Lipschütz: a systematic literature review and a diagnostic and therapeutic algorithm.
Sadoghi B, Stary G, Wolf P, Komericki P
J Eur Acad Dermatol Venereol 2020 Jul;34(7):1432-1439. Epub 2020 Feb 11 doi: 10.1111/jdv.16161. PMID: 31855308Free PMC Article
Risk factors and complications of lower limb cellulitis in Africa: a systematic review.
Tianyi FL, Mbanga CM, Danwang C, Agbor VN
BMJ Open 2018 Jul 23;8(7):e021175. doi: 10.1136/bmjopen-2017-021175. PMID: 30037869Free PMC Article
Topical agents and dressings for fungating wounds.
Adderley UJ, Holt IG
Cochrane Database Syst Rev 2014 May 15;2014(5):CD003948. doi: 10.1002/14651858.CD003948.pub3. PMID: 24832784Free PMC Article
Topical agents and dressings for fungating wounds.
Adderley U, Smith R
Cochrane Database Syst Rev 2007 Apr 18;(2):CD003948. doi: 10.1002/14651858.CD003948.pub2. PMID: 17443534

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