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Gallbladder Mucinous Cystic Neoplasm, Low Grade

MedGen UID:
474731
•Concept ID:
C3273098
•
Neoplastic Process
Synonyms: Gallbladder MCN with Low Grade Intraepithelial Neoplasia; Gallbladder Mucinous Cystic Neoplasm with Low Grade Intraepithelial Neoplasia; Gallbladder Mucinous Cystic Neoplasm, Low-Grade; Mucinous cystic neoplasm with low-grade intraepithelial neoplasia of gallbladder
SNOMED CT: Mucinous cystic neoplasm with low-grade intraepithelial neoplasia of gallbladder (1197308005)

Definition

A non-invasive mucinous cystic neoplasm that arises from the gallbladder epithelium. It is characterized by the presence of mild atypia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Mucinous Cystic Neoplasm, Low Grade

Recent clinical studies

Etiology

Cystadenomas of the liver and extrahepatic bile ducts: Morphologic and immunohistochemical characterization of the biliary and intestinal variants.
Albores-Saavedra J, Córdova-Ramón JC, Chablé-Montero F, Dorantes-Heredia R, Henson DE
Ann Diagn Pathol 2015 Jun;19(3):124-9. Epub 2015 Mar 6 doi: 10.1016/j.anndiagpath.2015.03.001. PMID: 25792461

Diagnosis

A case of mucinous cystic neoplasm of the gallbladder.
Sugawara S, Hirai I, Watanabe T, Tezuka K, Kimura W
Clin J Gastroenterol 2018 Oct;11(5):428-432. Epub 2018 Mar 13 doi: 10.1007/s12328-018-0850-8. PMID: 29536429
SATB2 Expression Distinguishes Ovarian Metastases of Colorectal and Appendiceal Origin From Primary Ovarian Tumors of Mucinous or Endometrioid Type.
Moh M, Krings G, Ates D, Aysal A, Kim GE, Rabban JT
Am J Surg Pathol 2016 Mar;40(3):419-32. doi: 10.1097/PAS.0000000000000553. PMID: 26551622
Analysis of trefoil factor family protein 1 (TFF1, pS2) expression in chronic cholecystitis and gallbladder carcinoma.
Kornprat P, Rehak P, Lemmerer M, Gogg-Kamerer M, Langner C
Virchows Arch 2005 May;446(5):505-10. Epub 2005 Apr 9 doi: 10.1007/s00428-005-1240-4. PMID: 15821928

Prognosis

SATB2 Expression Distinguishes Ovarian Metastases of Colorectal and Appendiceal Origin From Primary Ovarian Tumors of Mucinous or Endometrioid Type.
Moh M, Krings G, Ates D, Aysal A, Kim GE, Rabban JT
Am J Surg Pathol 2016 Mar;40(3):419-32. doi: 10.1097/PAS.0000000000000553. PMID: 26551622
Cystadenomas of the liver and extrahepatic bile ducts: Morphologic and immunohistochemical characterization of the biliary and intestinal variants.
Albores-Saavedra J, Córdova-Ramón JC, Chablé-Montero F, Dorantes-Heredia R, Henson DE
Ann Diagn Pathol 2015 Jun;19(3):124-9. Epub 2015 Mar 6 doi: 10.1016/j.anndiagpath.2015.03.001. PMID: 25792461
Analysis of trefoil factor family protein 1 (TFF1, pS2) expression in chronic cholecystitis and gallbladder carcinoma.
Kornprat P, Rehak P, Lemmerer M, Gogg-Kamerer M, Langner C
Virchows Arch 2005 May;446(5):505-10. Epub 2005 Apr 9 doi: 10.1007/s00428-005-1240-4. PMID: 15821928

Clinical prediction guides

SATB2 Expression Distinguishes Ovarian Metastases of Colorectal and Appendiceal Origin From Primary Ovarian Tumors of Mucinous or Endometrioid Type.
Moh M, Krings G, Ates D, Aysal A, Kim GE, Rabban JT
Am J Surg Pathol 2016 Mar;40(3):419-32. doi: 10.1097/PAS.0000000000000553. PMID: 26551622
Cytokeratins 7 and 20 in primary and secondary mucinous tumors of the ovary: analysis of coordinate immunohistochemical expression profiles and staining distribution in 179 cases.
Vang R, Gown AM, Barry TS, Wheeler DT, Yemelyanova A, Seidman JD, Ronnett BM
Am J Surg Pathol 2006 Sep;30(9):1130-9. doi: 10.1097/01.pas.0000213281.43036.bb. PMID: 16931958
Analysis of trefoil factor family protein 1 (TFF1, pS2) expression in chronic cholecystitis and gallbladder carcinoma.
Kornprat P, Rehak P, Lemmerer M, Gogg-Kamerer M, Langner C
Virchows Arch 2005 May;446(5):505-10. Epub 2005 Apr 9 doi: 10.1007/s00428-005-1240-4. PMID: 15821928

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