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Increased glomerular filtration rate

MedGen UID:
489766
•Concept ID:
C0856948
•
Finding
Synonym: Increased GFR
 
HPO: HP:0012214

Definition

An abnormal rise in the volume of water filtered out of plasma through glomerular capillary walls into Bowman's capsules per unit of time. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased glomerular filtration rate

Professional guidelines

PubMed

Tenofovir disoproxil fumarate for multiple nucleos(t)ide analogues treatment failure hepatitis B: Is monotherapy enough?
Liang X, Xie Q, Shang J, Tang H, Xu M, Meng Q, Zhang J, Gao P, Sheng J, Wang H, Jia J, Wang G, Wu S, Ping J, Hou J
J Gastroenterol Hepatol 2022 Mar;37(3):471-479. Epub 2022 Jan 6 doi: 10.1111/jgh.15757. PMID: 34894002Free PMC Article
A Review of the Efficacy and Safety of Genvoya® (Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide) in the Management of HIV-1 Infection.
Angione SA, Cherian SM, Özdener AE
J Pharm Pract 2018 Apr;31(2):216-221. Epub 2017 May 30 doi: 10.1177/0897190017710519. PMID: 28558493
Primary Care of the Patient with Chronic Kidney Disease.
Kiefer MM, Ryan MJ
Med Clin North Am 2015 Sep;99(5):935-52. doi: 10.1016/j.mcna.2015.05.003. PMID: 26320040

Recent clinical studies

Etiology

Chronic Kidney Disease and Pregnancy.
Hui D, Hladunewich MA
Obstet Gynecol 2019 Jun;133(6):1182-1194. doi: 10.1097/AOG.0000000000003256. PMID: 31135733
Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy.
Djukanović L, Ležaić V, Bukvić D, Mirković D, Marić I
Medicina (Kaunas) 2019 May 17;55(5) doi: 10.3390/medicina55050155. PMID: 31108979Free PMC Article
Homocysteine in pregnancy.
Murphy MM, Fernandez-Ballart JD
Adv Clin Chem 2011;53:105-37. doi: 10.1016/b978-0-12-385855-9.00005-9. PMID: 21404916
Cushing's syndrome, glucocorticoids and the kidney.
Smets P, Meyer E, Maddens B, Daminet S
Gen Comp Endocrinol 2010 Oct;169(1):1-10. Epub 2010 Jul 23 doi: 10.1016/j.ygcen.2010.07.004. PMID: 20655918
Metabolic syndrome and kidney disease.
Ritz E
Blood Purif 2008;26(1):59-62. Epub 2008 Jan 10 doi: 10.1159/000110566. PMID: 18182798

Diagnosis

Chronic Kidney Disease and Pregnancy.
Hui D, Hladunewich MA
Obstet Gynecol 2019 Jun;133(6):1182-1194. doi: 10.1097/AOG.0000000000003256. PMID: 31135733
Hyponatremia in visceral leishmaniasis.
Verde FA, Verde FA, Veronese FJ, Neto AS, Fuc G, Verde EM
Rev Inst Med Trop Sao Paulo 2010 Sep-Oct;52(5):253-8. doi: 10.1590/s0036-46652010000500006. PMID: 21049229
Metabolic syndrome and kidney disease.
Ritz E
Blood Purif 2008;26(1):59-62. Epub 2008 Jan 10 doi: 10.1159/000110566. PMID: 18182798
No need for glycosuria/proteinuria screen in pregnant women.
Alto WA
J Fam Pract 2005 Nov;54(11):978-83. PMID: 16266604
Does increased glomerular filtration rate or disturbed tubular function early in the course of childhood type 1 diabetes predict the development of nephropathy?
Lervang HH, Jensen S, Brøchner-Mortensen J, Ditzel J
Diabet Med 1992 Aug-Sep;9(7):635-40. doi: 10.1111/j.1464-5491.1992.tb01859.x. PMID: 1511570

Therapy

Chronic Kidney Disease and Pregnancy.
Hui D, Hladunewich MA
Obstet Gynecol 2019 Jun;133(6):1182-1194. doi: 10.1097/AOG.0000000000003256. PMID: 31135733
Immunomodulatory and Kidney-Protective Effects of the Human Chorionic Gonadotropin Derivate EA-230.
van Groenendael R, Kox M, van Eijk LT, Pickkers P
Nephron 2018;140(2):148-151. Epub 2018 Jul 6 doi: 10.1159/000490772. PMID: 29982253Free PMC Article
Homocysteine in pregnancy.
Murphy MM, Fernandez-Ballart JD
Adv Clin Chem 2011;53:105-37. doi: 10.1016/b978-0-12-385855-9.00005-9. PMID: 21404916
The role of vasopressin in vasodilatory septic shock.
Obritsch MD, Bestul DJ, Jung R, Fish DN, MacLaren R
Pharmacotherapy 2004 Aug;24(8):1050-63. doi: 10.1592/phco.24.11.1050.36144. PMID: 15338853
Clinical pharmacology of antibiotics and other drugs in cystic fibrosis.
Prandota J
Drugs 1988 May;35(5):542-78. doi: 10.2165/00003495-198835050-00004. PMID: 3293970

Prognosis

Metabolic syndrome and kidney disease.
Ritz E
Blood Purif 2008;26(1):59-62. Epub 2008 Jan 10 doi: 10.1159/000110566. PMID: 18182798
Abnormal blood pressure circadian rhythm: a target organ damage?
Izzedine H, Launay-Vacher V, Deray G
Int J Cardiol 2006 Mar 8;107(3):343-9. doi: 10.1016/j.ijcard.2005.03.046. PMID: 16503256
Renal effects of adenosine A1-receptor antagonists in congestive heart failure.
Gottlieb SS
Drugs 2001;61(10):1387-93. doi: 10.2165/00003495-200161100-00002. PMID: 11558828
Increased glomerular filtration rate as a predictor of diabetic nephropathy--an 8-year prospective study.
Rudberg S, Persson B, Dahlquist G
Kidney Int 1992 Apr;41(4):822-8. doi: 10.1038/ki.1992.126. PMID: 1513104
Does increased glomerular filtration rate or disturbed tubular function early in the course of childhood type 1 diabetes predict the development of nephropathy?
Lervang HH, Jensen S, Brøchner-Mortensen J, Ditzel J
Diabet Med 1992 Aug-Sep;9(7):635-40. doi: 10.1111/j.1464-5491.1992.tb01859.x. PMID: 1511570

Clinical prediction guides

Impact of increased kidney function on clinical and biological outcomes in real-world patients treated with Direct Oral Anticoagulants.
Corrochano M, Acosta-Isaac R, Plaza M, Muñoz R, Mojal S, Moret C, Souto JC
PLoS One 2022;17(12):e0278693. Epub 2022 Dec 9 doi: 10.1371/journal.pone.0278693. PMID: 36490245Free PMC Article
Immunomodulatory and Kidney-Protective Effects of the Human Chorionic Gonadotropin Derivate EA-230.
van Groenendael R, Kox M, van Eijk LT, Pickkers P
Nephron 2018;140(2):148-151. Epub 2018 Jul 6 doi: 10.1159/000490772. PMID: 29982253Free PMC Article
Impact of growth hormone hypersecretion on the adult human kidney.
Grunenwald S, Tack I, Chauveau D, Bennet A, Caron P
Ann Endocrinol (Paris) 2011 Dec;72(6):485-95. Epub 2011 Nov 17 doi: 10.1016/j.ando.2011.08.001. PMID: 22098791
Metabolic syndrome and kidney disease.
Ritz E
Blood Purif 2008;26(1):59-62. Epub 2008 Jan 10 doi: 10.1159/000110566. PMID: 18182798
Clinical pharmacology of antibiotics and other drugs in cystic fibrosis.
Prandota J
Drugs 1988 May;35(5):542-78. doi: 10.2165/00003495-198835050-00004. PMID: 3293970

Recent systematic reviews

Resveratrol may mildly improve renal function in the general adult population: A systematic review and meta-analysis of randomized controlled clinical trials.
Abdollahi S, Vajdi M, Meshkini F, Vasmehjani AA, Sangsefidi ZS, Clark CCT, Soltani S
Nutr Res 2023 May;113:1-13. Epub 2023 Mar 9 doi: 10.1016/j.nutres.2023.03.002. PMID: 36996691
Efficacy of Alprostadil in Preventing Contrast-Induced Nephropathy: A Systematic Review and Meta-Analysis.
Xu H, Wang H, Zhang C, Xiao J, Hua N, Tang X, Xie J, Zhang Z
Angiology 2021 Oct;72(9):878-888. Epub 2021 Apr 15 doi: 10.1177/00033197211004412. PMID: 33853365
Comparative effectiveness of different antihypertensive agents in kidney transplantation: a systematic review and meta-analysis.
Pisano A, Bolignano D, Mallamaci F, D'Arrigo G, Halimi JM, Persu A, Wuerzner G, Sarafidis P, Watschinger B, Burnier M, Zoccali C
Nephrol Dial Transplant 2020 May 1;35(5):878-887. doi: 10.1093/ndt/gfz092. PMID: 31143926
Renal hyperfiltration defined by high estimated glomerular filtration rate: A risk factor for cardiovascular disease and mortality.
Kanbay M, Ertuglu LA, Afsar B, Ozdogan E, Kucuksumer ZS, Ortiz A, Covic A, Kuwabara M, Cherney DZI, van Raalte DH, de Zeeuw D
Diabetes Obes Metab 2019 Nov;21(11):2368-2383. Epub 2019 Jul 29 doi: 10.1111/dom.13831. PMID: 31297976
Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients.
Karpe KM, Talaulikar GS, Walters GD
Cochrane Database Syst Rev 2017 Jul 21;7(7):CD006750. doi: 10.1002/14651858.CD006750.pub2. PMID: 28730648Free PMC Article

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