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Streptococcal sore throat

MedGen UID:
508129
•Concept ID:
C0036689
•
Disease or Syndrome
Synonyms: Septic sore throat; Strep throat; strep throat; Strept throat; Streptococcal angina; Streptococcal Pharyngitis; Streptococcal pharyngitis; streptococcal pharyngitis; streptococcal sore throat
SNOMED CT: Strept throat (43878008); Strep throat (43878008); Streptococcal sore throat (43878008); Streptococcal pharyngitis (43878008); Septic sore throat (43878008); Streptococcal angina (43878008)
 
Monarch Initiative: MONDO:0021783

Definition

Inflammation of the throat due to Streptococcus pyogenes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVStreptococcal sore throat

Professional guidelines

PubMed

Antibiotic treatment of children with sore throat.
Linder JA, Bates DW, Lee GM, Finkelstein JA
JAMA 2005 Nov 9;294(18):2315-22. doi: 10.1001/jama.294.18.2315. PMID: 16278359
Diagnosis and treatment of streptococcal sore throat.
Drug Ther Bull 1995 Feb;33(2):9-12. doi: 10.1136/dtb.1995.3329. PMID: 7587984
Evaluation of pharmacist management of streptococcal throat infections in a health maintenance organization.
Davis S
Am J Hosp Pharm 1978 May;35(5):561-6. PMID: 350043

Curated

UK NICE Diagnostics Guidance DG38, Rapid tests for group A streptococcal infections in people with a sore throat, 2019

Recent clinical studies

Etiology

Prevalence of group A β-hemolytic streptococcal throat carriage and prospective pilot surveillance of streptococcal sore throat in Ugandan school children.
DeWyer A, Scheel A, Webel AR, Longenecker CT, Kamarembo J, Aliku T, Engel ME, Bowen AC, Bwanga F, Hovis I, Chang A, Sarnacki R, Sable C, Dale JB, Carapetis J, Rwebembera J, Okello E, Beaton A
Int J Infect Dis 2020 Apr;93:245-251. Epub 2020 Jan 20 doi: 10.1016/j.ijid.2020.01.013. PMID: 31972290
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Prospective surveillance of streptococcal sore throat in a tropical country.
Steer AC, Jenney AW, Kado J, Good MF, Batzloff M, Magor G, Ritika R, Mulholland KE, Carapetis JR
Pediatr Infect Dis J 2009 Jun;28(6):477-82. doi: 10.1097/INF.0b013e318194b2af. PMID: 19483515
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Diagnosis

Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A
Int J Clin Pract 2017 Sep;71(9) Epub 2017 Sep 4 doi: 10.1111/ijcp.12961. PMID: 28869722
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Diagnosing streptococcal sore throat in adults: randomized controlled trial of in-office aids.
Worrall G, Hutchinson J, Sherman G, Griffiths J
Can Fam Physician 2007 Apr;53(4):666-71. PMID: 17872717Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Diagnosis and treatment of streptococcal sore throat.
Drug Ther Bull 1995 Feb;33(2):9-12. doi: 10.1136/dtb.1995.3329. PMID: 7587984

Therapy

Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842
Streptococcal sore throat.
Hughes MH
Br Med J 1972 Aug 5;3(5822):349. doi: 10.1136/bmj.3.5822.349. PMID: 4558308Free PMC Article
Streptococcal sore throat.
Br Med J 1972 Jul 15;3(5819):132. PMID: 4557080Free PMC Article

Prognosis

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A
Int J Clin Pract 2017 Sep;71(9) Epub 2017 Sep 4 doi: 10.1111/ijcp.12961. PMID: 28869722
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Addressing the burden of group A streptococcal disease in India.
Shet A, Kaplan E
Indian J Pediatr 2004 Jan;71(1):41-8. doi: 10.1007/BF02725655. PMID: 14979385
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Clinical prediction guides

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Pain relief of sore throat with a new anti-inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double-blind, placebo-controlled, international phase III study.
Bouroubi A, Donazzolo Y, Donath F, Eccles R, Russo M, Harambillet N, Gautier S, Montagne A
Int J Clin Pract 2017 Sep;71(9) Epub 2017 Sep 4 doi: 10.1111/ijcp.12961. PMID: 28869722
Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study.
Little P, Hobbs FD, Mant D, McNulty CA, Mullee M; PRISM investigators
Br J Gen Pract 2012 Nov;62(604):e787-94. doi: 10.3399/bjgp12X658322. PMID: 23211183Free PMC Article
Clinical course of suspected viral sore throat in young adults: cohort study.
Lindbaek M, Francis N, Cannings-John R, Butler CC, Hjortdahl P
Scand J Prim Health Care 2006 Jun;24(2):93-7. doi: 10.1080/02813430600638227. PMID: 16690557
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Recent systematic reviews

WITHDRAWN: Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers R, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2019 Mar 6;3(3):CD001976. doi: 10.1002/14651858.CD001976.pub2. PMID: 30839103Free PMC Article
Antistreptococcal interventions for guttate and chronic plaque psoriasis.
Owen CM, Chalmers RJ, O'Sullivan T, Griffiths CE
Cochrane Database Syst Rev 2000;(2):CD001976. doi: 10.1002/14651858.CD001976. PMID: 10796842

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NICE, 2019
      UK NICE Diagnostics Guidance DG38, Rapid tests for group A streptococcal infections in people with a sore throat, 2019

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

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