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Secondary Sjögren syndrome

MedGen UID:
508758
•Concept ID:
C0151450
•
Disease or Syndrome
Synonyms: Secondary Sjogren Syndrome; Secondary Sjogren's syndrome; Secondary Sjögren Syndrome; Secondary Sjögren's syndrome
SNOMED CT: Secondary Sjögren's syndrome (239915006); Secondary Sjögren syndrome (239915006); Secondary Sjogren's syndrome (239915006)

Definition

Sjogren syndrome that occurs with another systemic autoimmune disorder, such as systemic lupus erythematosus or rheumatoid arthritis. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSecondary Sjögren syndrome

Professional guidelines

PubMed

Major Salivary Gland Ultrasonography in the Diagnosis of Sjögren's Syndrome: A Place in the Diagnostic Criteria?
Jonsson MV, Baldini C
Rheum Dis Clin North Am 2016 Aug;42(3):501-17. doi: 10.1016/j.rdc.2016.03.008. PMID: 27431351
Diagnostic evaluation and classification criteria in Sjögren's Syndrome.
Gálvez J, Sáiz E, López P, Pina MF, Carrillo A, Nieto A, Pérez A, Marras C, Linares LF, Tornero C, Climent A, Rosique J, Reyes Y
Joint Bone Spine 2009 Jan;76(1):44-9. Epub 2008 Sep 30 doi: 10.1016/j.jbspin.2008.02.017. PMID: 18829369

Recent clinical studies

Etiology

Polyautoimmunity in systemic lupus erythematosus: secondary Sjogren syndrome.
Sieiro Santos C, Moriano Morales C, Álvarez Castro C, Díez Alvarez E
Z Rheumatol 2023 Jan;82(Suppl 1):68-73. Epub 2021 Jul 21 doi: 10.1007/s00393-021-01051-x. PMID: 34287668
Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.
Villarreal-Gonzalez AJ, Jocelyn Rivera-Alvarado I, Rodriguez-Gutierrez LA, Rodriguez-Garcia A
Rheumatol Int 2020 Aug;40(8):1249-1257. Epub 2020 Apr 2 doi: 10.1007/s00296-020-04568-7. PMID: 32242261
Secondary Sjögren syndrome: A case report using silver diamine fluoride and glass ionomer cement.
Young DA, Frostad-Thomas A, Gold J, Wong A
J Am Dent Assoc 2018 Aug;149(8):731-741. Epub 2018 May 24 doi: 10.1016/j.adaj.2018.03.021. PMID: 29805040
Meibomian Gland Dysfunction in Primary and Secondary Sjögren Syndrome.
Sullivan DA, Dana R, Sullivan RM, Krenzer KL, Sahin A, Arica B, Liu Y, Kam WR, Papas AS, Cermak JM
Ophthalmic Res 2018;59(4):193-205. Epub 2018 Apr 6 doi: 10.1159/000487487. PMID: 29627826
Anti-RO/SSA and anti-La/SSB antibodies: Association with mild lupus manifestations in 645 childhood-onset systemic lupus erythematosus.
Novak GV, Marques M, Balbi V, Gormezano NW, Kozu K, Sakamoto AP, Pereira RM, Terreri MT, Magalhães CS, Guariento A, Sallum AM, Marini R, Ferriani VP, Barbosa CM, de Castro TC, Ramos VC, Bonfá E, Silva CA
Autoimmun Rev 2017 Feb;16(2):132-135. Epub 2016 Dec 14 doi: 10.1016/j.autrev.2016.12.004. PMID: 27988434

Diagnosis

Polyautoimmunity in systemic lupus erythematosus: secondary Sjogren syndrome.
Sieiro Santos C, Moriano Morales C, Álvarez Castro C, Díez Alvarez E
Z Rheumatol 2023 Jan;82(Suppl 1):68-73. Epub 2021 Jul 21 doi: 10.1007/s00393-021-01051-x. PMID: 34287668
Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.
Villarreal-Gonzalez AJ, Jocelyn Rivera-Alvarado I, Rodriguez-Gutierrez LA, Rodriguez-Garcia A
Rheumatol Int 2020 Aug;40(8):1249-1257. Epub 2020 Apr 2 doi: 10.1007/s00296-020-04568-7. PMID: 32242261
Major Salivary Gland Ultrasonography in the Diagnosis of Sjögren's Syndrome: A Place in the Diagnostic Criteria?
Jonsson MV, Baldini C
Rheum Dis Clin North Am 2016 Aug;42(3):501-17. doi: 10.1016/j.rdc.2016.03.008. PMID: 27431351
Sjögren syndrome.
Srinivasan S, Slomovic AR
Compr Ophthalmol Update 2007 Jul-Aug;8(4):205-12. PMID: 17999834
Sjögren syndrome.
Tabbara KF, Vera-Cristo CL
Curr Opin Ophthalmol 2000 Dec;11(6):449-54. doi: 10.1097/00055735-200012000-00011. PMID: 11141640

Therapy

Comparison of clinical efficacies of autologous serum eye drops in patients with primary and secondary Sjögren syndrome.
Hwang J, Chung SH, Jeon S, Kwok SK, Park SH, Kim MS
Cornea 2014 Jul;33(7):663-7. doi: 10.1097/ICO.0000000000000147. PMID: 24886995
Sjögren syndrome.
Srinivasan S, Slomovic AR
Compr Ophthalmol Update 2007 Jul-Aug;8(4):205-12. PMID: 17999834
Sjögren syndrome.
Tabbara KF, Vera-Cristo CL
Curr Opin Ophthalmol 2000 Dec;11(6):449-54. doi: 10.1097/00055735-200012000-00011. PMID: 11141640
Silica-associated connective tissue disease. A study of 24 cases.
Koeger AC, Lang T, Alcaix D, Milleron B, Rozenberg S, Chaibi P, Arnaud J, Mayaud C, Camus JP, Bourgeois P
Medicine (Baltimore) 1995 Sep;74(5):221-37. doi: 10.1097/00005792-199509000-00001. PMID: 7565064
Primary Sjogren syndrome: clinical and immunopathologic features.
Fox RI, Howell FV, Bone RC, Michelson P
Semin Arthritis Rheum 1984 Nov;14(2):77-105. doi: 10.1016/0049-0172(84)90001-5. PMID: 6399627

Prognosis

Polyautoimmunity in systemic lupus erythematosus: secondary Sjogren syndrome.
Sieiro Santos C, Moriano Morales C, Álvarez Castro C, Díez Alvarez E
Z Rheumatol 2023 Jan;82(Suppl 1):68-73. Epub 2021 Jul 21 doi: 10.1007/s00393-021-01051-x. PMID: 34287668
Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.
Villarreal-Gonzalez AJ, Jocelyn Rivera-Alvarado I, Rodriguez-Gutierrez LA, Rodriguez-Garcia A
Rheumatol Int 2020 Aug;40(8):1249-1257. Epub 2020 Apr 2 doi: 10.1007/s00296-020-04568-7. PMID: 32242261
Sjögren syndrome.
Srinivasan S, Slomovic AR
Compr Ophthalmol Update 2007 Jul-Aug;8(4):205-12. PMID: 17999834
Sjögren syndrome.
Tabbara KF, Vera-Cristo CL
Curr Opin Ophthalmol 2000 Dec;11(6):449-54. doi: 10.1097/00055735-200012000-00011. PMID: 11141640
Primary Sjogren syndrome: clinical and immunopathologic features.
Fox RI, Howell FV, Bone RC, Michelson P
Semin Arthritis Rheum 1984 Nov;14(2):77-105. doi: 10.1016/0049-0172(84)90001-5. PMID: 6399627

Clinical prediction guides

Polyautoimmunity in systemic lupus erythematosus: secondary Sjogren syndrome.
Sieiro Santos C, Moriano Morales C, Álvarez Castro C, Díez Alvarez E
Z Rheumatol 2023 Jan;82(Suppl 1):68-73. Epub 2021 Jul 21 doi: 10.1007/s00393-021-01051-x. PMID: 34287668
Diagnostic value of salivary gland ultrasonography for secondary Sjögren syndrome in patients with systemic lupus erythematosus.
Hammam N, Elzohri MH, Elsonbaty A, Eldaly ZH, Hammam O, Tarik D, Ibrahim HM, Gheita TA
Lupus 2022 Aug;31(9):1045-1053. Epub 2022 May 6 doi: 10.1177/09612033221100154. PMID: 35514317
Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome.
Villarreal-Gonzalez AJ, Jocelyn Rivera-Alvarado I, Rodriguez-Gutierrez LA, Rodriguez-Garcia A
Rheumatol Int 2020 Aug;40(8):1249-1257. Epub 2020 Apr 2 doi: 10.1007/s00296-020-04568-7. PMID: 32242261
Comparison of Tear Osmolarity in Rheumatoid Arthritis Patients With and Without Secondary Sjogren Syndrome.
Ng ALK, Choy BNK, Chan TCY, Wong IYH, Lai JSM, Mok MY
Cornea 2017 Jul;36(7):805-809. doi: 10.1097/ICO.0000000000001227. PMID: 28486313
Anti-RO/SSA and anti-La/SSB antibodies: Association with mild lupus manifestations in 645 childhood-onset systemic lupus erythematosus.
Novak GV, Marques M, Balbi V, Gormezano NW, Kozu K, Sakamoto AP, Pereira RM, Terreri MT, Magalhães CS, Guariento A, Sallum AM, Marini R, Ferriani VP, Barbosa CM, de Castro TC, Ramos VC, Bonfá E, Silva CA
Autoimmun Rev 2017 Feb;16(2):132-135. Epub 2016 Dec 14 doi: 10.1016/j.autrev.2016.12.004. PMID: 27988434

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