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Subdural empyema

MedGen UID:
52531
•Concept ID:
C0038539
•
Disease or Syndrome
Synonyms: Empyema, Subdural; Subdural Empyema; Subdural Empyemas
SNOMED CT: Empyema (collection of pus), subdural space (37660004); Subdural abscess (37660004); Subdural empyema (37660004)
 
Monarch Initiative: MONDO:0006984

Definition

An intracranial or rarely intraspinal suppurative process invading the space between the inner surface of the dura mater and the outer surface of the arachnoid. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubdural empyema

Professional guidelines

PubMed

Management of spinal infection: a review of the literature.
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
Management of bacterial central nervous system infections.
Brouwer MC, van de Beek D
Handb Clin Neurol 2017;140:349-364. doi: 10.1016/B978-0-444-63600-3.00019-2. PMID: 28187809
Diagnosis and management of brain abscess and subdural empyema.
Bernardini GL
Curr Neurol Neurosci Rep 2004 Nov;4(6):448-56. doi: 10.1007/s11910-004-0067-8. PMID: 15509445

Recent clinical studies

Etiology

Hyperbaric oxygen for intracranial abscess.
Tomoye EO, Moon RE
Undersea Hyperb Med 2021 First Quarter;48(1):97-102. doi: 10.22462/01.03.2021.12. PMID: 33648039
Intracranial subdural empyemas and epidural abscesses in children.
Lundy P, Kaufman C, Garcia D, Partington MD, Grabb PA
J Neurosurg Pediatr 2019 Jul 1;24(1):14-21. Epub 2019 Mar 22 doi: 10.3171/2019.1.PEDS18434. PMID: 31553545
Bacterial Infections of the Central Nervous System.
Suthar R, Sankhyan N
Indian J Pediatr 2019 Jan;86(1):60-69. Epub 2018 Jan 3 doi: 10.1007/s12098-017-2477-z. PMID: 29297142
Management of bacterial central nervous system infections.
Brouwer MC, van de Beek D
Handb Clin Neurol 2017;140:349-364. doi: 10.1016/B978-0-444-63600-3.00019-2. PMID: 28187809
Neurological sequelae of bacterial meningitis.
Lucas MJ, Brouwer MC, van de Beek D
J Infect 2016 Jul;73(1):18-27. Epub 2016 Apr 19 doi: 10.1016/j.jinf.2016.04.009. PMID: 27105658

Diagnosis

Bacterial Infections of the Central Nervous System.
Suthar R, Sankhyan N
Indian J Pediatr 2019 Jan;86(1):60-69. Epub 2018 Jan 3 doi: 10.1007/s12098-017-2477-z. PMID: 29297142
Management of spinal infection: a review of the literature.
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
Pediatric intracranial abscesses.
Bonfield CM, Sharma J, Dobson S
J Infect 2015 Jun;71 Suppl 1:S42-6. Epub 2015 Apr 24 doi: 10.1016/j.jinf.2015.04.012. PMID: 25917804
Brain infections.
Sarrazin JL, Bonneville F, Martin-Blondel G
Diagn Interv Imaging 2012 Jun;93(6):473-90. Epub 2012 Jun 5 doi: 10.1016/j.diii.2012.04.020. PMID: 22677301
Subdural empyema.
Brennan MR
Am Fam Physician 1995 Jan;51(1):157-62. PMID: 7810468

Therapy

Oral sequential therapy in the treatment of post-surgical epidural abscess and subdural empyema.
Rubiñán P, Pérez-Rodríguez MT, Domínguez A, Sousa A, Lima O, Rubianes M, Conde C, Álvarez-Fernández M
Infection 2022 Oct;50(5):1385-1389. Epub 2022 Apr 23 doi: 10.1007/s15010-022-01814-x. PMID: 35460496
Bacterial Infections of the Central Nervous System.
Suthar R, Sankhyan N
Indian J Pediatr 2019 Jan;86(1):60-69. Epub 2018 Jan 3 doi: 10.1007/s12098-017-2477-z. PMID: 29297142
Management of spinal infection: a review of the literature.
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
Subdural empyema in children.
Hendaus MA
Glob J Health Sci 2013 Aug 14;5(6):54-9. doi: 10.5539/gjhs.v5n6p54. PMID: 24171874Free PMC Article
Acute sinusitis.
Diaz I, Bamberger DM
Semin Respir Infect 1995 Mar;10(1):14-20. PMID: 7761709

Prognosis

Management of spinal infection: a review of the literature.
Lener S, Hartmann S, Barbagallo GMV, Certo F, Thomé C, Tschugg A
Acta Neurochir (Wien) 2018 Mar;160(3):487-496. Epub 2018 Jan 22 doi: 10.1007/s00701-018-3467-2. PMID: 29356895Free PMC Article
Neurological sequelae of bacterial meningitis.
Lucas MJ, Brouwer MC, van de Beek D
J Infect 2016 Jul;73(1):18-27. Epub 2016 Apr 19 doi: 10.1016/j.jinf.2016.04.009. PMID: 27105658
Brain infections.
Sarrazin JL, Bonneville F, Martin-Blondel G
Diagn Interv Imaging 2012 Jun;93(6):473-90. Epub 2012 Jun 5 doi: 10.1016/j.diii.2012.04.020. PMID: 22677301
Subdural empyema.
Brennan MR
Am Fam Physician 1995 Jan;51(1):157-62. PMID: 7810468
Brain abscess and subdural empyema.
Levy RM
Curr Opin Neurol 1994 Jun;7(3):223-8. doi: 10.1097/00019052-199406000-00008. PMID: 7915942

Clinical prediction guides

Oral sequential therapy in the treatment of post-surgical epidural abscess and subdural empyema.
Rubiñán P, Pérez-Rodríguez MT, Domínguez A, Sousa A, Lima O, Rubianes M, Conde C, Álvarez-Fernández M
Infection 2022 Oct;50(5):1385-1389. Epub 2022 Apr 23 doi: 10.1007/s15010-022-01814-x. PMID: 35460496
Pyogenic brain abscess and subdural empyema: presentation, management, and factors predicting outcome.
Widdrington JD, Bond H, Schwab U, Price DA, Schmid ML, McCarron B, Chadwick DR, Narayanan M, Williams J, Ong E
Infection 2018 Dec;46(6):785-792. Epub 2018 Jul 27 doi: 10.1007/s15010-018-1182-9. PMID: 30054798
Infantile and childhood bacterial meningitis.
Lepage P, Dan B
Handb Clin Neurol 2013;112:1115-25. doi: 10.1016/B978-0-444-52910-7.00031-3. PMID: 23622319
Acute sinusitis.
Diaz I, Bamberger DM
Semin Respir Infect 1995 Mar;10(1):14-20. PMID: 7761709
Brain abscess and subdural empyema.
Levy RM
Curr Opin Neurol 1994 Jun;7(3):223-8. doi: 10.1097/00019052-199406000-00008. PMID: 7915942

Recent systematic reviews

Sinogenic Intracranial Suppuration in Children: Systematic Review and Meta-analysis.
Milinis K, Thompson N, Atsmoni SC, Sharma SD
Otolaryngol Head Neck Surg 2022 Aug;167(2):215-223. Epub 2021 Sep 7 doi: 10.1177/01945998211043847. PMID: 34491863
Considerations in the management of giant frontal mucoceles with significant intracranial extension: A systematic review.
Stokken J, Wali E, Woodard T, Recinos PF, Sindwani R
Am J Rhinol Allergy 2016 Jul;30(4):301-5. doi: 10.2500/ajra.2016.30.4323. PMID: 27456600
Systematic review and case report: Intracranial complications of pediatric sinusitis.
Patel NA, Garber D, Hu S, Kamat A
Int J Pediatr Otorhinolaryngol 2016 Jul;86:200-12. Epub 2016 May 11 doi: 10.1016/j.ijporl.2016.05.009. PMID: 27260608
Unusual complications associated with third molar surgery: a systematic review.
Brauer HU
Quintessence Int 2009 Jul-Aug;40(7):565-72. PMID: 19626231

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