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Fixed pigmented erythema

MedGen UID:
526203
Concept ID:
C0221242
Pathologic Function
Synonyms: FDE - Fixed drug eruption; Fixed Drug Eruption; Fixed drug eruption; fixed drug eruption; fixed pigmented erythema
SNOMED CT: Fixed drug eruption (73692007); FDE - Fixed drug eruption (73692007)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0017395
Orphanet: ORPHA293812

Definition

Fixed drug eruption is a rare toxic dermatosis disorder characterized by the appearance of a drug-induced rash which typically manifests with small (diameter less than 8 cm), erythematous, round, sometimes painful, plaques that result in long-lasting pigmentation and which recurr (usually at the same site) upon reexposure to the causative medication. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFixed pigmented erythema

Professional guidelines

PubMed

Lancellotta V, Kovács G, Tagliaferri L, Perrucci E, Rembielak A, Stingeni L, Tramontana M, Hansel K, Colloca G, Saldi S, Valentini V, Aristei C
J Geriatr Oncol 2019 May;10(3):514-517. Epub 2018 Oct 9 doi: 10.1016/j.jgo.2018.09.009. PMID: 30314955
Özkaya E
J Am Acad Dermatol 2013 Aug;69(2):e51-8. Epub 2012 Oct 6 doi: 10.1016/j.jaad.2012.08.019. PMID: 23044075
Kang HY, Valerio L, Bahadoran P, Ortonne JP
Am J Clin Dermatol 2009;10(4):251-60. doi: 10.2165/00128071-200910040-00005. PMID: 19489658

Recent clinical studies

Diagnosis

Castelain F, Humbert P
Curr Drug Saf 2012 Nov 1;7(5):332-8. doi: 10.2174/157488612805076516. PMID: 23441982

Therapy

Castelain F, Humbert P
Curr Drug Saf 2012 Nov 1;7(5):332-8. doi: 10.2174/157488612805076516. PMID: 23441982
Prescrire Int 2007 Feb;16(87):21. PMID: 17323528

Prognosis

Castelain F, Humbert P
Curr Drug Saf 2012 Nov 1;7(5):332-8. doi: 10.2174/157488612805076516. PMID: 23441982

Clinical prediction guides

Castelain F, Humbert P
Curr Drug Saf 2012 Nov 1;7(5):332-8. doi: 10.2174/157488612805076516. PMID: 23441982
Yoboue P, Sangare A, Kaloga M, Kouadio A, Djedje MA
Int J Dermatol 2005 Oct;44 Suppl 1:33-4. doi: 10.1111/j.1365-4632.2005.02808.x. PMID: 16187956

Supplemental Content

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