U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Late systolic murmur

MedGen UID:
534396
•Concept ID:
C0232261
•
Finding
Synonyms: Late Systolic Heart Murmur; Late Systolic Murmur
SNOMED CT: Late systolic murmur (65254001)
 
HPO: HP:0031666

Definition

A murmur that occurs in the latter phase of systole. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLate systolic murmur

Professional guidelines

PubMed

Recent developments in the diagnosis and management of mitral valve prolapse.
Devereux RB
Curr Opin Cardiol 1995 Mar;10(2):107-16. doi: 10.1097/00001573-199503000-00003. PMID: 7787275
Mitral valve prolapse: etiology, diagnosis, and management.
de Leon AC Jr
Postgrad Med 1980 Jan;67(1):66-9, 72-7. doi: 10.1080/00325481.1980.11715338. PMID: 7350567
The systolic click-murmur syndrome: clinical recognition and management.
O'rourke RA, Crawford MH
Curr Probl Cardiol 1976 Mar-Apr;1(1):1-60. doi: 10.1016/s0146-2806(76)80006-0. PMID: 1017208

Recent clinical studies

Etiology

Mitral valve prolapse with a late-systolic regurgitant murmur may be associated with significant hemodynamic consequences.
Ahmed MI, Sanagala T, Denney T, Inusah S, McGiffin D, Knowlan D, O'Rourke RA, Dell'Italia LJ
Am J Med Sci 2009 Aug;338(2):113-5. doi: 10.1097/MAJ.0b013e31819d5ec6. PMID: 19561453
Mitral valve prolapse. A common cardiac diagnosis in women.
McLachlan J, Reddy PC, Ratts TE
J La State Med Soc 1998 Feb;150(2):92-6. PMID: 9510616
Recent developments in the diagnosis and management of mitral valve prolapse.
Devereux RB
Curr Opin Cardiol 1995 Mar;10(2):107-16. doi: 10.1097/00001573-199503000-00003. PMID: 7787275
Mitral valve prolapse.
Devereux RB
J Am Med Womens Assoc (1972) 1994 Nov-Dec;49(6):192-7. PMID: 7829819
Understanding mitral valve prolapse (MVP).
Schatz IJ
Herz 1988 Aug;13(4):235-42. PMID: 3049286

Diagnosis

Mitral valve prolapse.
Devereux RB
J Am Med Womens Assoc (1972) 1994 Nov-Dec;49(6):192-7. PMID: 7829819
Mitral valve prolapse.
Cheng TO
Dis Mon 1987 Sep;33(9):481-534. doi: 10.1016/0011-5029(87)90005-8. PMID: 3308381
Mitral valve prolapse.
Gould L, Gopalaswamy C
Angiology 1984 May;35(5):290-9. doi: 10.1177/000331978403500505. PMID: 6144281
Mitral valve prolapse.
Wigle ED, Rakowski H, Ranganathan N, Silver MC
Annu Rev Med 1976;27:165-80. doi: 10.1146/annurev.me.27.020176.001121. PMID: 779595
Mitral valve prolapse.
Devereux RB, Perloff JK, Reichek N, Josephson ME
Circulation 1976 Jul;54(1):3-14. doi: 10.1161/01.cir.54.1.3. PMID: 776440

Therapy

Predisposing factors for severe mitral regurgitation in idiopathic mitral valve prolapse.
Fukuda N, Oki T, Iuchi A, Tabata T, Manabe K, Kageji Y, Sasaki M, Yamada H, Ito S
Am J Cardiol 1995 Sep 1;76(7):503-7. doi: 10.1016/s0002-9149(99)80139-8. PMID: 7653453
Mitral valve prolapse.
Gould L, Gopalaswamy C
Angiology 1984 May;35(5):290-9. doi: 10.1177/000331978403500505. PMID: 6144281
Mitral valve prolapse: etiology, diagnosis, and management.
de Leon AC Jr
Postgrad Med 1980 Jan;67(1):66-9, 72-7. doi: 10.1080/00325481.1980.11715338. PMID: 7350567
Infective endocarditis in the billowing mitral leaflet syndrome.
Lachman AS, Bramwell-Jones DM, Lakier JB, Pocock WA, Barlow JB
Br Heart J 1975 Mar;37(3):326-30. doi: 10.1136/hrt.37.3.326. PMID: 1138736Free PMC Article
The familial occurrence of the syndrome of mid-late systolic click and late systolic murmur.
Shell WE, Walton JA, Clifford ME, Willis PW 3rd
Circulation 1969 Mar;39(3):327-37. doi: 10.1161/01.cir.39.3.327. PMID: 5766802

Prognosis

Mitral valve prolapse. A common cardiac diagnosis in women.
McLachlan J, Reddy PC, Ratts TE
J La State Med Soc 1998 Feb;150(2):92-6. PMID: 9510616
Mitral valve prolapse.
Devereux RB
J Am Med Womens Assoc (1972) 1994 Nov-Dec;49(6):192-7. PMID: 7829819
The relationship between clinical and echocardiographic findings in mitral valve prolapse.
Rueda B, Arvan S
Herz 1988 Oct;13(5):277-83. PMID: 3053380
Mitral valve prolapse.
Gould L, Gopalaswamy C
Angiology 1984 May;35(5):290-9. doi: 10.1177/000331978403500505. PMID: 6144281
The systolic click-murmur syndrome: clinical recognition and management.
O'rourke RA, Crawford MH
Curr Probl Cardiol 1976 Mar-Apr;1(1):1-60. doi: 10.1016/s0146-2806(76)80006-0. PMID: 1017208

Clinical prediction guides

Assessment of autonomic dysfunction and anxiety levels in patients with mitral valve prolapse.
Orhan AL, Sayar N, Nurkalem Z, Uslu N, Erdem I, Erdem EC, Erer HB, Soylu O, Emre A, Sayar K, Eren M
Turk Kardiyol Dern Ars 2009 Jun;37(4):226-33. PMID: 19717954
Teaching cardiac auscultation: effectiveness of a patient-centered teaching conference on improving cardiac auscultatory skills.
March SK, Bedynek JL Jr, Chizner MA
Mayo Clin Proc 2005 Nov;80(11):1443-8. doi: 10.4065/80.11.1443. PMID: 16295024
Understanding mitral valve prolapse (MVP).
Schatz IJ
Herz 1988 Aug;13(4):235-42. PMID: 3049286
M mode and cross-sectional echocardiographic features of flail posterior mitral leaflets.
Child JS, Skorton DJ, Taylor RD, Krivokapich J, Abbasi AS, Wong M, Shah PD
Am J Cardiol 1979 Dec;44(7):1383-90. doi: 10.1016/0002-9149(79)90457-0. PMID: 506941
The determinants of onset of mitral valve prolapse in the systolic click-late systolic murmur syndrome.
Mathey DG, Decoodt PR, Allen HN, Swan HJ
Circulation 1976 May;53(5):872-8. doi: 10.1161/01.cir.53.5.872. PMID: 1260992

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...