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Nihilistic delusion

MedGen UID:
535460
•Concept ID:
C0233677
•
Mental or Behavioral Dysfunction
Synonyms: Delire de negation; Délire de négation; Nihilism
SNOMED CT: Délire de négation (247679002); Delire de negation (247679002); Nihilistic delusion (247679002); Nihilism (247679002)
 
HPO: HP:5200421

Definition

A false belief associated with the nonexistence of the "self," specific body parts, or the world. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNihilistic delusion

Recent clinical studies

Etiology

Cotard's syndrome in the postoperative period following head and neck cancer surgery - A case report.
Thakur N, Gupta M, Gupta R, Mishra S
Indian J Cancer 2022 Apr-Jun;59(2):273-275. doi: 10.4103/ijc.IJC_825_20. PMID: 35946188
Factor Structure of Cotard's Syndrome: Systematic Review of Case Reports.
Huarcaya-Victoria J, Bojórquez-De la Torre J, De la Cruz-Oré J
Rev Colomb Psiquiatr (Engl Ed) 2020 Jul-Sep;49(3):187-193. Epub 2018 Dec 3 doi: 10.1016/j.rcp.2018.10.008. PMID: 32888662
'I am dead': Cotard syndrome and dementia.
Cipriani G, Nuti A, Danti S, Picchi L, Di Fiorino M
Int J Psychiatry Clin Pract 2019 Jun;23(2):149-156. Epub 2019 Mar 8 doi: 10.1080/13651501.2018.1529248. PMID: 30848970

Diagnosis

Factor Structure of Cotard's Syndrome: Systematic Review of Case Reports.
Huarcaya-Victoria J, Bojórquez-De la Torre J, De la Cruz-Oré J
Rev Colomb Psiquiatr (Engl Ed) 2020 Jul-Sep;49(3):187-193. Epub 2018 Dec 3 doi: 10.1016/j.rcp.2018.10.008. PMID: 32888662
Fluctuating Cotard syndrome in a patient with advanced Parkinson disease.
Solla P, Cannas A, Orofino G, Marrosu F
Neurologist 2015 Feb;19(3):70-2. doi: 10.1097/NRL.0000000000000010. PMID: 25692512
Self-mutilation of the nose in a schizophrenic patient with Cotard syndrome.
Ghaffari-Nejad A, Kerdegari M, Reihani-Kermani H
Arch Iran Med 2007 Oct;10(4):540-2. PMID: 17903066

Therapy

Cotard's Syndrome after breast surgery successfully treated with aripiprazole augmentation of escitalopram: a case report.
De Berardis D, Brucchi M, Serroni N, Rapini G, Campanella D, Vellante F, Valchera A, Fornaro M, Iasevoli F, Mazza M, Lucidi G, Martinotti G, di Giannantonio M
Riv Psichiatr 2015 Mar-Apr;50(2):95-8. doi: 10.1708/1872.20458. PMID: 25994620
Fluctuating Cotard syndrome in a patient with advanced Parkinson disease.
Solla P, Cannas A, Orofino G, Marrosu F
Neurologist 2015 Feb;19(3):70-2. doi: 10.1097/NRL.0000000000000010. PMID: 25692512
Cotard's syndrome with glioblastoma multiforme.
Reich M, Comet B, Le Rhun E, Ramirez C
Palliat Support Care 2012 Jun;10(2):135-9. Epub 2012 Feb 24 doi: 10.1017/S1478951511000757. PMID: 22360815
Transcranial magnetic stimulation for treatment resistant depression: six case reports and review.
Krisanaprakornkit T, Paholpak S, Tassaniyom K, Pimpanit V
J Med Assoc Thai 2010 May;93(5):580-6. PMID: 20524444

Prognosis

Cotard's syndrome with glioblastoma multiforme.
Reich M, Comet B, Le Rhun E, Ramirez C
Palliat Support Care 2012 Jun;10(2):135-9. Epub 2012 Feb 24 doi: 10.1017/S1478951511000757. PMID: 22360815

Recent systematic reviews

Factor Structure of Cotard's Syndrome: Systematic Review of Case Reports.
Huarcaya-Victoria J, Bojórquez-De la Torre J, De la Cruz-Oré J
Rev Colomb Psiquiatr (Engl Ed) 2020 Jul-Sep;49(3):187-193. Epub 2018 Dec 3 doi: 10.1016/j.rcp.2018.10.008. PMID: 32888662
'I am dead': Cotard syndrome and dementia.
Cipriani G, Nuti A, Danti S, Picchi L, Di Fiorino M
Int J Psychiatry Clin Pract 2019 Jun;23(2):149-156. Epub 2019 Mar 8 doi: 10.1080/13651501.2018.1529248. PMID: 30848970

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