U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Peripheral cyanosis

MedGen UID:
536409
•Concept ID:
C0235532
•
Finding
SNOMED CT: Peripheral cyanosis (95442007)
 
HPO: HP:0034033

Definition

Bluish discoloration of the distal extremities (hands, fingertips, toes), and can sometimes involve circumoral and periorbital areas. Mucous membranes are generally not involved. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPeripheral cyanosis

Professional guidelines

PubMed

Acute respiratory failure in goitre patients qualified for operative treatment.
Buła G, Paliga M, Koziołek H, Mucha R, Gawrychowski J
Endokrynol Pol 2013;64(3):215-9. PMID: 23873426

Recent clinical studies

Etiology

Assessment of Tissue Perfusion Using the Peripheral Perfusion Index and Lactate Clearance in Shock in Pediatric Patients.
Bazaraa H, Roby S, Salah E, Algebaly H
Shock 2021 Dec 1;56(6):933-938. doi: 10.1097/SHK.0000000000001811. PMID: 34014888
Prehospital clinical presentation in patients with acute coronary syndrome complicated by cardiogenic shock: A single center study.
Jaskiewicz F, Zielinska M
Aust Crit Care 2019 Jul;32(4):293-298. Epub 2018 Sep 10 doi: 10.1016/j.aucc.2018.08.002. PMID: 30213588
Pulmonary Alveolar Proteinosis: A Rare Cause of Respiratory Failure.
Munir Z, Khosa MZ, Qazi MY
J Coll Physicians Surg Pak 2015 Jul;25(7):541-2. PMID: 26208564
Acute respiratory failure in goitre patients qualified for operative treatment.
Buła G, Paliga M, Koziołek H, Mucha R, Gawrychowski J
Endokrynol Pol 2013;64(3):215-9. PMID: 23873426
Efficacy of granisetron in preventing postanesthetic shivering.
Sajedi P, Yaraghi A, Moseli HA
Acta Anaesthesiol Taiwan 2008 Dec;46(4):166-70. doi: 10.1016/S1875-4597(09)60004-7. PMID: 19097963

Diagnosis

A rare combination of methemoglobinemia and carboxyhemoglobinemia in pesticide poisoning.
Arva K, Sharma A
Am J Emerg Med 2022 Dec;62:148.e5-148.e7. Epub 2022 Sep 15 doi: 10.1016/j.ajem.2022.09.010. PMID: 36163065
Assessment of Tissue Perfusion Using the Peripheral Perfusion Index and Lactate Clearance in Shock in Pediatric Patients.
Bazaraa H, Roby S, Salah E, Algebaly H
Shock 2021 Dec 1;56(6):933-938. doi: 10.1097/SHK.0000000000001811. PMID: 34014888
Lyme aortitis.
Correia RR, Cruz F, Martin S, André ME
BMJ Case Rep 2020 Jan 14;13(1) doi: 10.1136/bcr-2019-231957. PMID: 31941668Free PMC Article
Seventy-six-year-old man with progressive dyspnoea.
Martínez-Milla J, Maestre Bastardo ÁJ, Cortés M
Heart 2019 Jan;105(1):74-88. Epub 2018 Oct 3 doi: 10.1136/heartjnl-2018-313779. PMID: 30282641
Clinical signs of impending death in cancer patients.
Hui D, dos Santos R, Chisholm G, Bansal S, Silva TB, Kilgore K, Crovador CS, Yu X, Swartz MD, Perez-Cruz PE, Leite Rde A, Nascimento MS, Reddy S, Seriaco F, Yennu S, Paiva CE, Dev R, Hall S, Fajardo J, Bruera E
Oncologist 2014 Jun;19(6):681-7. Epub 2014 Apr 23 doi: 10.1634/theoncologist.2013-0457. PMID: 24760709Free PMC Article

Therapy

Silica associated systemic sclerosis: an occupational health hazard.
Shivakumar DS, Kamath NS, Naik A
BMJ Case Rep 2023 Jan 17;16(1) doi: 10.1136/bcr-2022-253952. PMID: 36653045Free PMC Article
A rare combination of methemoglobinemia and carboxyhemoglobinemia in pesticide poisoning.
Arva K, Sharma A
Am J Emerg Med 2022 Dec;62:148.e5-148.e7. Epub 2022 Sep 15 doi: 10.1016/j.ajem.2022.09.010. PMID: 36163065
A Case of Dapsone-induced Mild Methemoglobinemia with Dyspnea and Cyanosis.
Hayama Y, Imanishi H, Yoshimoto N, Sugawara K, Tsuruta D
Acta Dermatovenerol Croat 2020 Dec;28(4):249-250. PMID: 33835002
Terlipressin-Induced Peripheral Cyanosis in a Patient with Liver Cirrhosis and Hepatorenal Syndrome.
Chiang CW, Lin YJ, Huang YB
Am J Case Rep 2019 Jan 2;20:5-9. doi: 10.12659/AJCR.913150. PMID: 30600312Free PMC Article
A non-fatal intoxication with a high-dose sodium nitrate.
Joosen D, Stolk L, Henry R
BMJ Case Rep 2014 May 30;2014 doi: 10.1136/bcr-2014-204825. PMID: 24879739Free PMC Article

Prognosis

Assessment of Tissue Perfusion Using the Peripheral Perfusion Index and Lactate Clearance in Shock in Pediatric Patients.
Bazaraa H, Roby S, Salah E, Algebaly H
Shock 2021 Dec 1;56(6):933-938. doi: 10.1097/SHK.0000000000001811. PMID: 34014888
A visually striking case of primary acrocyanosis: A rare cause of the blue digit.
Kent JT, Carr D
Am J Emerg Med 2021 Feb;40:227.e3-227.e4. Epub 2020 Aug 1 doi: 10.1016/j.ajem.2020.07.064. PMID: 32800682Free PMC Article
Seventy-six-year-old man with progressive dyspnoea.
Martínez-Milla J, Maestre Bastardo ÁJ, Cortés M
Heart 2019 Jan;105(1):74-88. Epub 2018 Oct 3 doi: 10.1136/heartjnl-2018-313779. PMID: 30282641
On the detection of peripheral cyanosis in individuals with distinct levels of cutaneous pigmentation.
Baranoski GVG, Van Leeuwen SR, Chen TF
Annu Int Conf IEEE Eng Med Biol Soc 2017 Jul;2017:4260-4264. doi: 10.1109/EMBC.2017.8037797. PMID: 29060838
Thoracic ectopia cordis.
Shad J, Budhwani K, Biswas R
BMJ Case Rep 2012 Sep 30;2012 doi: 10.1136/bcr.11.2011.5241. PMID: 23035158Free PMC Article

Clinical prediction guides

Effects of aerospace environments on the cardiovascular system.
Ercan E
Anatol J Cardiol 2021 Aug;25(Suppl 1):3-6. doi: 10.5152/AnatolJCardiol.2021.S103. PMID: 34464290Free PMC Article
Assessment of Tissue Perfusion Using the Peripheral Perfusion Index and Lactate Clearance in Shock in Pediatric Patients.
Bazaraa H, Roby S, Salah E, Algebaly H
Shock 2021 Dec 1;56(6):933-938. doi: 10.1097/SHK.0000000000001811. PMID: 34014888
On the detection of peripheral cyanosis in individuals with distinct levels of cutaneous pigmentation.
Baranoski GVG, Van Leeuwen SR, Chen TF
Annu Int Conf IEEE Eng Med Biol Soc 2017 Jul;2017:4260-4264. doi: 10.1109/EMBC.2017.8037797. PMID: 29060838
Acute respiratory failure in goitre patients qualified for operative treatment.
Buła G, Paliga M, Koziołek H, Mucha R, Gawrychowski J
Endokrynol Pol 2013;64(3):215-9. PMID: 23873426
Clinical profile of Chikungunya in infants.
Valamparampil JJ, Chirakkarot S, Letha S, Jayakumar C, Gopinathan KM
Indian J Pediatr 2009 Feb;76(2):151-5. Epub 2009 Mar 28 doi: 10.1007/s12098-009-0045-x. PMID: 19330303

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...