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Nasal glial heterotopia

MedGen UID:
539951
Concept ID:
C0266490
Neoplastic Process
Synonyms: Ectopic Glial Tissue; Glial Choristoma; Nasal Glial Heterotopia; nasal glial heterotopia; Nasal Glioma; Nasal glioma; nasal glioma; Neuroglial Heterotopia
SNOMED CT: Nasal glial heterotopia (5645008); Nasal glioma (5645008)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0015392
Orphanet: ORPHA141112

Definition

Nasal glial heterotopia is a rare developmental abnormality presenting usually at birth or in early childhood (rarely in adulthood) as a benign, non-pulsatile mass that can lead to nasal obstruction, deformation of the septum and nasal bone, and respiratory distress if untreated. Nasal glial heterotopias have no communication with the central nervous system; however an associated defect in the cribriform plate is sometimes reported. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasal glial heterotopia
Follow this link to review classifications for Nasal glial heterotopia in Orphanet.

Recent clinical studies

Etiology

Gilani A, Kleinschmidt-DeMasters BK
Childs Nerv Syst 2022 Jan;38(1):63-75. Epub 2021 Sep 25 doi: 10.1007/s00381-021-05369-4. PMID: 34562130
Zhang W, Tang L, Wang P, Ge W, Ni X
Medicine (Baltimore) 2020 Jul 17;99(29):e21200. doi: 10.1097/MD.0000000000021200. PMID: 32702883Free PMC Article
Gan W, Xiang Y, Tang Y, He X, Hu J, Yang F, Liu S, Xian J, Meng J
Medicine (Baltimore) 2018 Sep;97(38):e12000. doi: 10.1097/MD.0000000000012000. PMID: 30235657Free PMC Article
Yorgancılar E, Yıldırım M, Gün R, Büyükbayram H, Meriç F
Kulak Burun Bogaz Ihtis Derg 2010 Sep-Oct;20(5):267-70. PMID: 20815807
Penner CR, Thompson L
Ann Diagn Pathol 2003 Dec;7(6):354-9. doi: 10.1016/j.anndiagpath.2003.09.010. PMID: 15018118

Diagnosis

Ren F, Bressler L, Pruitt L, Wang H, Liu L, Elston DM
J Am Acad Dermatol 2023 Dec;89(6):1238-1244. Epub 2023 Aug 19 doi: 10.1016/j.jaad.2023.06.062. PMID: 37598328
Gallego Compte M, Menter T, Guertler N, Negoias S
Acta Otorhinolaryngol Ital 2022 Aug;42(4):317-324. doi: 10.14639/0392-100X-N1977. PMID: 36254649Free PMC Article
Gilani A, Kleinschmidt-DeMasters BK
Childs Nerv Syst 2022 Jan;38(1):63-75. Epub 2021 Sep 25 doi: 10.1007/s00381-021-05369-4. PMID: 34562130
Yan YY, Zhou ZY, Bi J, Fu Y
Int J Pediatr Otorhinolaryngol 2020 Feb;129:109728. Epub 2019 Oct 15 doi: 10.1016/j.ijporl.2019.109728. PMID: 31739082
Penner CR, Thompson L
Ann Diagn Pathol 2003 Dec;7(6):354-9. doi: 10.1016/j.anndiagpath.2003.09.010. PMID: 15018118

Therapy

Cerdá-Nicolás M, Sanchez Fernandez de Sevilla C, Lopez-Ginés C, Peydro-Olaya A, Llombart-Bosch A
Clin Neuropathol 2002 Mar-Apr;21(2):66-71. PMID: 12005254

Prognosis

Yan YY, Zhou ZY, Bi J, Fu Y
Int J Pediatr Otorhinolaryngol 2020 Feb;129:109728. Epub 2019 Oct 15 doi: 10.1016/j.ijporl.2019.109728. PMID: 31739082

Clinical prediction guides

Gilani A, Kleinschmidt-DeMasters BK
Childs Nerv Syst 2022 Jan;38(1):63-75. Epub 2021 Sep 25 doi: 10.1007/s00381-021-05369-4. PMID: 34562130

Recent systematic reviews

Gallego Compte M, Menter T, Guertler N, Negoias S
Acta Otorhinolaryngol Ital 2022 Aug;42(4):317-324. doi: 10.14639/0392-100X-N1977. PMID: 36254649Free PMC Article

Supplemental Content

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