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Anejaculation

MedGen UID:
548660
Concept ID:
C0278106
Pathologic Function
Synonyms: Absence of ejaculation; Ejaculation failure; Ejaculatory incompetence; Failure of ejaculation
SNOMED CT: Anejaculation (248782001); Failure of ejaculation (248782001); Absence of ejaculation (42288005); Ejaculation failure (42288005)
 
HPO: HP:0012879

Definition

Inability to ejaculate. [from HPO]

Professional guidelines

PubMed

Dickstein DR, Edwards CR, Lehrer EJ, Tarras ES, Gallitto M, Sfakianos J, Galsky MD, Stock R, Safer JD, Rosser BRS, Marshall DC
Nat Rev Urol 2023 Jun;20(6):332-355. Epub 2023 May 22 doi: 10.1038/s41585-023-00778-3. PMID: 37217695Free PMC Article
Kim P, Clavijo RI
Urol Oncol 2022 Sep;40(9):389-394. Epub 2020 Aug 26 doi: 10.1016/j.urolonc.2020.08.006. PMID: 32859462
Kamischke A, Nieschlag E
Hum Reprod Update 1999 Sep-Oct;5(5):448-74. doi: 10.1093/humupd/5.5.448. PMID: 10582783

Recent clinical studies

Etiology

Leisegang K, Opuwari CS, Moichela F, Finelli R
Medicina (Kaunas) 2023 Sep 6;59(9) doi: 10.3390/medicina59091607. PMID: 37763726Free PMC Article
Daneshmand S, Cary C, Masterson T, Einhorn L, Adra N, Boorjian SA, Kollmannsberger C, Schuckman A, So A, Black P, Bagrodia A, Skinner E, Alemozaffar M, Brand T, Eggener S, Pierorazio P, Stratton K, Nappi L, Nichols C, Luo C, Li M, Hu B
J Clin Oncol 2023 Jun 1;41(16):3009-3018. Epub 2023 Mar 13 doi: 10.1200/JCO.22.00624. PMID: 36913642
Huang Z, Berg WT
Fertil Steril 2021 Sep;116(3):625-629. doi: 10.1016/j.fertnstert.2021.07.1200. PMID: 34462097
Bearelly P, Avellino GJ
Fertil Steril 2021 Sep;116(3):611-617. doi: 10.1016/j.fertnstert.2021.07.1199. PMID: 34462095
Ohl DA
Urol Clin North Am 1993 Feb;20(1):181-8. PMID: 8434436

Diagnosis

Leisegang K, Opuwari CS, Moichela F, Finelli R
Medicina (Kaunas) 2023 Sep 6;59(9) doi: 10.3390/medicina59091607. PMID: 37763726Free PMC Article
Colonnello E, Limoncin E, Ciocca G, Sansone A, Mollaioli D, Balercia G, Porst H, Zhang H, Yu X, Zhang Y, Jannini EA
Sex Med Rev 2022 Jan;10(1):113-129. Epub 2021 Oct 5 doi: 10.1016/j.sxmr.2021.08.001. PMID: 34620562
Forbes CM, Flannigan R, Paduch DA
Sex Med Rev 2018 Jul;6(3):419-428. Epub 2018 Feb 17 doi: 10.1016/j.sxmr.2017.12.005. PMID: 29463441
Ohl DA, Quallich SA, Sønksen J, Brackett NL, Lynne CM
Urol Clin North Am 2008 May;35(2):211-20, viii. doi: 10.1016/j.ucl.2008.01.014. PMID: 18423241
Kamischke A, Nieschlag E
Hum Reprod Update 1999 Sep-Oct;5(5):448-74. doi: 10.1093/humupd/5.5.448. PMID: 10582783

Therapy

Leisegang K, Opuwari CS, Moichela F, Finelli R
Medicina (Kaunas) 2023 Sep 6;59(9) doi: 10.3390/medicina59091607. PMID: 37763726Free PMC Article
Daneshmand S, Cary C, Masterson T, Einhorn L, Adra N, Boorjian SA, Kollmannsberger C, Schuckman A, So A, Black P, Bagrodia A, Skinner E, Alemozaffar M, Brand T, Eggener S, Pierorazio P, Stratton K, Nappi L, Nichols C, Luo C, Li M, Hu B
J Clin Oncol 2023 Jun 1;41(16):3009-3018. Epub 2023 Mar 13 doi: 10.1200/JCO.22.00624. PMID: 36913642
Bearelly P, Avellino GJ
Fertil Steril 2021 Sep;116(3):611-617. doi: 10.1016/j.fertnstert.2021.07.1199. PMID: 34462095
Kamischke A, Nieschlag E
Hum Reprod Update 1999 Sep-Oct;5(5):448-74. doi: 10.1093/humupd/5.5.448. PMID: 10582783
Witt MA, Grantmyre JE
World J Urol 1993;11(2):89-95. doi: 10.1007/BF00182035. PMID: 8343800

Prognosis

Desai A, Chen R, Cayetano A, Jayasena CN, Minhas S
Andrology 2023 Feb;11(2):379-398. Epub 2022 Aug 26 doi: 10.1111/andr.13262. PMID: 35933708
Nguyen DD, Mantri SS, Zorn KC, Misraï V, Elterman D, Bhojani N
Urology 2021 Jul;153:250-255. Epub 2021 Jan 20 doi: 10.1016/j.urology.2021.01.023. PMID: 33482130
Orum MH, Egilmez OB
Rev Int Androl 2020 Apr-Jun;18(2):79-83. Epub 2018 Nov 22 doi: 10.1016/j.androl.2018.09.001. PMID: 30473331
Chéhensse C, Facchinetti P, Bahrami S, Andrey P, Soler JM, Chrétien F, Bernabé J, Clément P, Denys P, Giuliano F
Ann Neurol 2017 Jan;81(1):35-45. Epub 2016 Dec 5 doi: 10.1002/ana.24819. PMID: 27917533
Sullivan JF, Stember DS, Deveci S, Akin-Olugbade Y, Mulhall JP
J Sex Med 2013 May;10(5):1410-6. Epub 2013 Feb 22 doi: 10.1111/jsm.12101. PMID: 23433425

Clinical prediction guides

Demirci A, Başar H
Urologia 2024 May;91(2):403-412. Epub 2023 Oct 11 doi: 10.1177/03915603231204077. PMID: 37818833
Desai A, Chen R, Cayetano A, Jayasena CN, Minhas S
Andrology 2023 Feb;11(2):379-398. Epub 2022 Aug 26 doi: 10.1111/andr.13262. PMID: 35933708
Chen J, Yang J, Huang X, Wang Q, Lu C, Liu S, Chen Y, Ni L
J Sex Med 2020 Dec;17(12):2331-2340. Epub 2020 Oct 4 doi: 10.1016/j.jsxm.2020.09.002. PMID: 33023837
Örtqvist L, Fossum M, Andersson M, Nordenström A, Frisén L, Holmdahl G, Nordenskjöld A
Andrology 2017 Mar;5(2):286-293. Epub 2016 Dec 19 doi: 10.1111/andr.12309. PMID: 27992969
Chéhensse C, Facchinetti P, Bahrami S, Andrey P, Soler JM, Chrétien F, Bernabé J, Clément P, Denys P, Giuliano F
Ann Neurol 2017 Jan;81(1):35-45. Epub 2016 Dec 5 doi: 10.1002/ana.24819. PMID: 27917533

Recent systematic reviews

Leisegang K, Opuwari CS, Moichela F, Finelli R
Medicina (Kaunas) 2023 Sep 6;59(9) doi: 10.3390/medicina59091607. PMID: 37763726Free PMC Article
Röscher P, Sathiram R, Milios JE, van Wyk JM
Syst Rev 2022 Jan 3;11(1):2. doi: 10.1186/s13643-021-01865-5. PMID: 34980265Free PMC Article
Mehta A, Sigman M
Fertil Steril 2015 Nov;104(5):1074-81. Epub 2015 Oct 1 doi: 10.1016/j.fertnstert.2015.09.024. PMID: 26432530
Gacci M, Ficarra V, Sebastianelli A, Corona G, Serni S, Shariat SF, Maggi M, Zattoni F, Carini M, Novara G
J Sex Med 2014 Jun;11(6):1554-66. Epub 2014 Apr 7 doi: 10.1111/jsm.12525. PMID: 24708055
Chéhensse C, Bahrami S, Denys P, Clément P, Bernabé J, Giuliano F
Hum Reprod Update 2013 Sep-Oct;19(5):507-26. Epub 2013 Jul 2 doi: 10.1093/humupd/dmt029. PMID: 23820516

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