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Adenosis

MedGen UID:: 569524
•Concept ID:: C0334050
•: Disease or Syndrome

SNOMED CT:

Adenosis (57597008)

Definition

Any disease or disorder of a gland, characterized by abnormal development or enlargement of the gland. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAdenosis

Pathological process
- Disease
  - Disorder by Site
    - Connective and Soft Tissue Disorder
      - Disorder of soft tissue
        Non-Neoplastic Soft Tissue Disorder
        Adenosis
        Vaginal adenosis

Professional guidelines

PubMed

Vulvovaginal manifestations in Stevens-Johnson syndrome and toxic epidermal necrolysis: Prevention and treatment.

O'Brien KF, Bradley SE, Mitchell CM, Cardis MA, Mauskar MM, Pasieka HB
J Am Acad Dermatol 2021 Aug;85(2):523-528. Epub 2019 Aug 19 doi: 10.1016/j.jaad.2019.08.031. PMID: 31437544

Core needle biopsy of benign, borderline and in-situ problematic lesions of the breast: Diagnosis, differential diagnosis and immunohistochemistry.

Rosa M, Agosto-Arroyo E
Ann Diagn Pathol 2019 Dec;43:151407. Epub 2019 Sep 3 doi: 10.1016/j.anndiagpath.2019.151407. PMID: 31634810

Pseudohyperplastic prostate carcinoma: histologic patterns and differential diagnosis.

Arista-Nasr J, Martínez-Benítez B, Aguilar-Ayala EL, Aleman-Sanchez CN, Bornstein-Quevedo L, Albores-Saavedra J
Ann Diagn Pathol 2015 Aug;19(4):253-60. Epub 2015 May 22 doi: 10.1016/j.anndiagpath.2015.04.009. PMID: 26101154

See all (37)

Recent clinical studies

Etiology

Histopathology of non-mass-like breast lesions on ultrasound.

Yamaguchi R, Watanabe H, Mihara Y, Yamaguchi M, Tanaka M
J Med Ultrason (2001) 2023 Jul;50(3):375-380. Epub 2023 Feb 11 doi: 10.1007/s10396-023-01286-y. PMID: 36773105 Free PMC Article

Adenomyoepithelioma of the breast: a proposal for classification.

Rakha E, Tan PH, Ellis I, Quinn C
Histopathology 2021 Oct;79(4):465-479. Epub 2021 Jun 13 doi: 10.1111/his.14380. PMID: 33829532

Benign mimics of prostate cancer.

Egevad L, Delahunt B, Furusato B, Tsuzuki T, Yaxley J, Samaratunga H
Pathology 2021 Jan;53(1):26-35. Epub 2020 Oct 16 doi: 10.1016/j.pathol.2020.08.006. PMID: 33070957

Conventional and contrast-enhanced ultrasound features in sclerosing adenosis and correlation with pathology.

Shao S, Yao M, Li X, Li C, Chen J, Li G, Jia C, Wu R
Clin Hemorheol Microcirc 2021;77(2):173-181. doi: 10.3233/CH-200943. PMID: 32924999

Newly Described Entities in Salivary Gland Pathology.

Skálová A, Gnepp DR, Lewis JS Jr, Hunt JL, Bishop JA, Hellquist H, Rinaldo A, Vander Poorten V, Ferlito A
Am J Surg Pathol 2017 Aug;41(8):e33-e47. doi: 10.1097/PAS.0000000000000883. PMID: 28614209

See all (314)

Diagnosis

Apocrine lesions of the breast.

Quinn CM, D'Arcy C, Wells C
Virchows Arch 2022 Jan;480(1):177-189. Epub 2021 Sep 18 doi: 10.1007/s00428-021-03185-4. PMID: 34537861 Free PMC Article

Adenomyoepithelioma of the breast: a proposal for classification.

Rakha E, Tan PH, Ellis I, Quinn C
Histopathology 2021 Oct;79(4):465-479. Epub 2021 Jun 13 doi: 10.1111/his.14380. PMID: 33829532

Sclerosing Polycystic Adenoma.

Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220

Microglandular Adenosis and Associated Invasive Carcinoma.

Kravtsov O, Jorns JM
Arch Pathol Lab Med 2020 Jan;144(1):42-46. Epub 2019 May 22 doi: 10.5858/arpa.2019-0049-RA. PMID: 31116044

The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology.

Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626

See all (486)

Therapy

Conventional and contrast-enhanced ultrasound features in sclerosing adenosis and correlation with pathology.

Shao S, Yao M, Li X, Li C, Chen J, Li G, Jia C, Wu R
Clin Hemorheol Microcirc 2021;77(2):173-181. doi: 10.3233/CH-200943. PMID: 32924999

The development of cervical and vaginal adenosis as a result of diethylstilbestrol exposure in utero.

Laronda MM, Unno K, Butler LM, Kurita T
Differentiation 2012 Oct;84(3):252-60. Epub 2012 Jun 6 doi: 10.1016/j.diff.2012.05.004. PMID: 22682699 Free PMC Article

Desmoid tumors.

Biermann JS
Curr Treat Options Oncol 2000 Aug;1(3):262-6. doi: 10.1007/s11864-000-0038-5. PMID: 12057169

The daughters of diethylstilbestrol. Lessons from an error.

Tournaire M, Lepercq J, Epelboin S
Eur J Obstet Gynecol Reprod Biol 1997 Dec;75(1):25-7. doi: 10.1016/s0301-2115(97)00206-6. PMID: 9447342

Gynecological malignancy.

Compton WC
Alaska Med 1981 Mar-Apr;23(2):13-7. PMID: 7246964

See all (191)

Prognosis

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review.

de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748

Sclerosing Polycystic Adenoma.

Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220

Microglandular adenosis of the breast: a deceptive and still mysterious benign lesion.

Foschini MP, Eusebi V
Hum Pathol 2018 Dec;82:1-9. Epub 2018 Jun 24 doi: 10.1016/j.humpath.2018.06.025. PMID: 29949742

Newly Described Entities in Salivary Gland Pathology.

Skálová A, Gnepp DR, Lewis JS Jr, Hunt JL, Bishop JA, Hellquist H, Rinaldo A, Vander Poorten V, Ferlito A
Am J Surg Pathol 2017 Aug;41(8):e33-e47. doi: 10.1097/PAS.0000000000000883. PMID: 28614209

Desmoid tumors.

Biermann JS
Curr Treat Options Oncol 2000 Aug;1(3):262-6. doi: 10.1007/s11864-000-0038-5. PMID: 12057169

See all (185)

Clinical prediction guides

Microglandular adenosis of the breast: a deceptive and still mysterious benign lesion.

Foschini MP, Eusebi V
Hum Pathol 2018 Dec;82:1-9. Epub 2018 Jun 24 doi: 10.1016/j.humpath.2018.06.025. PMID: 29949742

Incidental vaginal müllerianosis.

Val-Bernal JF, Mayorga M
Pathol Res Pract 2016 Jun;212(6):568-72. Epub 2016 Feb 26 doi: 10.1016/j.prp.2016.02.023. PMID: 26970930

Pseudohyperplastic prostate carcinoma: histologic patterns and differential diagnosis.

The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology.

Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626

Desmoid tumors.

Biermann JS
Curr Treat Options Oncol 2000 Aug;1(3):262-6. doi: 10.1007/s11864-000-0038-5. PMID: 12057169

See all (213)

Recent systematic reviews

Clinicopathological profile of sclerosing polycystic adenoma/adenosis: A systematic review.

de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748

Sclerosing Polycystic Adenosis of the Parotid Gland: A Systematic Review and Report of 2 New Cases.

Espinosa CA, Rua L, Torres HE, Fernández Del Valle Á, Fernandes RP, Devicente JC
J Oral Maxillofac Surg 2017 May;75(5):984-993. Epub 2016 Nov 2 doi: 10.1016/j.joms.2016.10.031. PMID: 27888671

The developmental origin of cervical and vaginal epithelium and their clinical consequences: a systematic review.

Reich O, Fritsch H
J Low Genit Tract Dis 2014 Oct;18(4):358-60. doi: 10.1097/LGT.0000000000000023. PMID: 24977630

Oestrogen supplementation, mainly diethylstilbestrol, for preventing miscarriages and other adverse pregnancy outcomes.

Bamigboye AA, Morris J
Cochrane Database Syst Rev 2003;2003(3):CD004353. doi: 10.1002/14651858.CD004353. PMID: 12918007 Free PMC Article

See all (4)

MedGen

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Adenosis

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

Recent activity