U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Trabecular Adenoma

MedGen UID:
60000
•Concept ID:
C0205651
•
Neoplastic Process
Synonyms: Adenoma, Trabecular; Adenomas, Trabecular; Trabecular Adenomas
SNOMED CT: Trabecular adenoma (21930005)

Definition

A benign epithelial neoplasm characterized by the presence of a trabecular glandular architectural pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTrabecular Adenoma

Professional guidelines

PubMed

Hyalinizing trabecular adenoma of the thyroid--morphology and differential diagnosis.
Schmid KW, Mesewinkel F, Böcker W
Acta Med Austriaca 1996;23(1-2):65-8. PMID: 8767518

Recent clinical studies

Etiology

GLIS Rearrangement is a Genomic Hallmark of Hyalinizing Trabecular Tumor of the Thyroid Gland.
Nikiforova MN, Nikitski AV, Panebianco F, Kaya C, Yip L, Williams M, Chiosea SI, Seethala RR, Roy S, Condello V, Santana-Santos L, Wald AI, Carty SE, Ferris RL, El-Naggar AK, Nikiforov YE
Thyroid 2019 Feb;29(2):161-173. doi: 10.1089/thy.2018.0791. PMID: 30648929Free PMC Article
Thyroid Bethesda reporting category, 'suspicious for papillary thyroid carcinoma', pitfalls and clues to optimize the use of this category.
Mahajan A, Lin X, Nayar R
Cytopathology 2013 Apr;24(2):85-91. Epub 2012 Feb 22 doi: 10.1111/j.1365-2303.2012.00966.x. PMID: 22356185
Histopathological study of solitary nodules of thyroid.
Khadilkar UN, Maji P
Kathmandu Univ Med J (KUMJ) 2008 Oct-Dec;6(24):486-90. doi: 10.3126/kumj.v6i4.1740. PMID: 19483430
Hyalinizing trabecular carcinoma of the thyroid gland: report of two cases of follicular cell thyroid carcinoma with hyalinizing trabecular pattern.
González-Cámpora R, Fuentes-Vaamonde E, Hevia-Vázquez A, Otal-Salaverri C, Villar-Rodriguez JL, Galera-Davidson H
Ultrastruct Pathol 1998 Jan-Feb;22(1):39-46. doi: 10.3109/01913129809032256. PMID: 9491214
Hyalinizing trabecular carcinoma of thyroid gland.
McCluggage WG, Sloan JM
Histopathology 1996 Apr;28(4):357-62. doi: 10.1046/j.1365-2559.1996.d01-432.x. PMID: 8732345

Diagnosis

Non-hyalinizing trabecular thyroid adenoma: a novel thyroid tumor with diagnostic pitfalls of hyalinizing trabecular adenoma and medullary thyroid carcinoma.
Hirokawa M, Matsuse M, Mitsutake N, Suzuki A, Higuchi M, Hayashi T, Kamma H, Miyauchi A, Akamizu T
Diagn Pathol 2023 Jun 20;18(1):74. doi: 10.1186/s13000-023-01361-5. PMID: 37340328Free PMC Article
The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology.
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Hyalinizing trabecular adenoma of the thyroid gland.
Bishop JA, Ali SZ
Diagn Cytopathol 2011 Apr;39(4):306-10. Epub 2010 Aug 20 doi: 10.1002/dc.21413. PMID: 20730896
A practical diagnostic approach to solid/trabecular nodules in the thyroid.
Volante M, Papotti M
Endocr Pathol 2008 Summer;19(2):75-81. doi: 10.1007/s12022-008-9023-5. PMID: 18409025
Hyalinizing trabecular adenoma of the thyroid--morphology and differential diagnosis.
Schmid KW, Mesewinkel F, Böcker W
Acta Med Austriaca 1996;23(1-2):65-8. PMID: 8767518

Therapy

A case of trabecular adenoma of the thyroid with black pigmentation.
Sharma V, Cui H, Whalen G, Khan A, Torres M
Thyroid 2007 Jun;17(6):593-4. doi: 10.1089/thy.2006.0151. PMID: 17614784
Prevalence and incidence of cytoplasmic yellow bodies in thyroid neoplasms.
Rothenberg HJ, Goellner JR, Carney JA
Arch Pathol Lab Med 2003 Jun;127(6):715-7. doi: 10.5858/2003-127-715-PAIOCY. PMID: 12741896

Prognosis

Hyaline matrix in hyalinizing trabecular tumor: Findings in fine-needle aspiration smears.
Bakuła-Zalewska E, Cameron R, Gałczyński JP, Domanski HA
Diagn Cytopathol 2015 Sep;43(9):710-3. Epub 2014 Oct 29 doi: 10.1002/dc.23224. PMID: 25352467
Thyroid Bethesda reporting category, 'suspicious for papillary thyroid carcinoma', pitfalls and clues to optimize the use of this category.
Mahajan A, Lin X, Nayar R
Cytopathology 2013 Apr;24(2):85-91. Epub 2012 Feb 22 doi: 10.1111/j.1365-2303.2012.00966.x. PMID: 22356185
Histopathological study of solitary nodules of thyroid.
Khadilkar UN, Maji P
Kathmandu Univ Med J (KUMJ) 2008 Oct-Dec;6(24):486-90. doi: 10.3126/kumj.v6i4.1740. PMID: 19483430
Prevalence and incidence of cytoplasmic yellow bodies in thyroid neoplasms.
Rothenberg HJ, Goellner JR, Carney JA
Arch Pathol Lab Med 2003 Jun;127(6):715-7. doi: 10.5858/2003-127-715-PAIOCY. PMID: 12741896
Hyalinizing trabecular adenoma of the thyroid gland.
Hicks MJ, Batsakis JG
Ann Otol Rhinol Laryngol 1993 Mar;102(3 Pt 1):239-40. doi: 10.1177/000348949310200313. PMID: 8457127

Clinical prediction guides

Non-hyalinizing trabecular thyroid adenoma: a novel thyroid tumor with diagnostic pitfalls of hyalinizing trabecular adenoma and medullary thyroid carcinoma.
Hirokawa M, Matsuse M, Mitsutake N, Suzuki A, Higuchi M, Hayashi T, Kamma H, Miyauchi A, Akamizu T
Diagn Pathol 2023 Jun 20;18(1):74. doi: 10.1186/s13000-023-01361-5. PMID: 37340328Free PMC Article
The wonderful colors of the hematoxylin-eosin stain in diagnostic surgical pathology.
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Hyalinizing trabecular adenoma of the thyroid revisited: a histologic and immunohistochemical study of thyroid lesions with prominent trabecular architecture and sclerosis.
Galgano MT, Mills SE, Stelow EB
Am J Surg Pathol 2006 Oct;30(10):1269-73. doi: 10.1097/01.pas.0000209858.13035.0a. PMID: 17001158
Cytologic features of hyalinizing trabecular adenoma of the thyroid.
Kuma S, Hirokawa M, Miyauchi A, Kakudo K, Katayama S
Acta Cytol 2003 May-Jun;47(3):399-404. doi: 10.1159/000326540. PMID: 12789921
Hyalinizing trabecular adenoma of the thyroid. A report of two cases with cytologic, histologic and immunohistochemical findings.
Kaleem Z, Dávila RM
Acta Cytol 1997 May-Jun;41(3):883-8. doi: 10.1159/000332722. PMID: 9167720

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...