U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pulmonary blastoma

MedGen UID:
61645
Concept ID:
C0206629
Neoplastic Process
Synonyms: Blastoma, Pulmonary; Blastomas, Pulmonary; Pulmonary Blastoma; Pulmonary Blastomas
SNOMED CT: Pulmonary blastoma (189815007); Pneumoblastoma (189815007); Pulmonary blastoma (43149009); Pneumoblastoma (43149009)
Modes of inheritance:
Non-Mendelian inheritance
MedGen UID:
109109
Concept ID:
C0600599
Genetic Function
Source: Orphanet
A mode of inheritance that depends on genetic determinants in more than one gene.
 
Monarch Initiative: MONDO:0005933
Orphanet: ORPHA64741

Definition

A biphasic primary lung neoplasm, belonging to the group of sarcomatoid lung carcinomas (SLCs). The tumor contains both an epithelial well-differentiated component, showing tubular architecture resembling the normal fetal lung, and a mesenchymal undifferentiated stroma with a so-called ''blastema-like'' configuration that resembles an embryonic lung. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPulmonary blastoma
Follow this link to review classifications for Pulmonary blastoma in Orphanet.

Professional guidelines

PubMed

Panozzi M, Alì G, Proietti A, Melfi F, Zirafa CC, Lucchi M, Fontanini G
Pathologica 2023 Jun;115(3):164-171. doi: 10.32074/1591-951X-847. PMID: 37387441Free PMC Article
Suster S
Semin Diagn Pathol 1995 May;12(2):140-57. PMID: 7638447
Calabria R, Srikanth MS, Chamberlin K, Bloch J, Atkinson JB
Am Surg 1993 Mar;59(3):192-6. PMID: 8476159

Recent clinical studies

Etiology

Leung SS, Donuru A, Kandula V, Parekh MR, Saul D
Semin Ultrasound CT MR 2022 Feb;43(1):61-72. Epub 2021 May 15 doi: 10.1053/j.sult.2021.05.007. PMID: 35164911
Tsamis I, Chachali SP, Gomatou G, Trontzas I, Mitsogianni M, Syrigos N, Vamvakaris I, Kotteas E
Adv Respir Med 2021;89(5):511-519. doi: 10.5603/ARM.a2021.0085. PMID: 34725809
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S
Eur J Pediatr 2017 Dec;176(12):1559-1571. Epub 2017 Oct 19 doi: 10.1007/s00431-017-3032-7. PMID: 29046943
Puligandla PS, Laberge JM
Clin Perinatol 2012 Jun;39(2):331-47. doi: 10.1016/j.clp.2012.04.009. PMID: 22682383
Weissferdt A, Moran CA
Adv Anat Pathol 2011 May;18(3):179-89. doi: 10.1097/PAP.0b013e318216980c. PMID: 21490435

Diagnosis

Dehner LP, Schultz KAP, Hill DA
Pediatr Dev Pathol 2023 May-Jun;26(3):241-249. Epub 2023 Feb 21 doi: 10.1177/10935266221146823. PMID: 37334833
Leung SS, Donuru A, Kandula V, Parekh MR, Saul D
Semin Ultrasound CT MR 2022 Feb;43(1):61-72. Epub 2021 May 15 doi: 10.1053/j.sult.2021.05.007. PMID: 35164911
Leblanc C, Baron M, Desselas E, Phan MH, Rybak A, Thouvenin G, Lauby C, Irtan S
Eur J Pediatr 2017 Dec;176(12):1559-1571. Epub 2017 Oct 19 doi: 10.1007/s00431-017-3032-7. PMID: 29046943
Anand R, Narula MK, Chadha R, Chander J, Jain M
J Indian Med Assoc 2013 Feb;111(2):128-9. PMID: 24003574
Puligandla PS, Laberge JM
Clin Perinatol 2012 Jun;39(2):331-47. doi: 10.1016/j.clp.2012.04.009. PMID: 22682383

Therapy

Chen Y, Chen H, Yu R, Zeng X, Tian D, Pu Q, Liu Y
Lung Cancer 2024 Mar;189:107476. Epub 2024 Jan 24 doi: 10.1016/j.lungcan.2024.107476. PMID: 38280290
Wang F, Zhuang L, Liang J, Li L, Wang H, Tang J, Zeng J, Liu W
Pediatr Pulmonol 2022 Sep;57(9):2237-2243. Epub 2022 Jun 13 doi: 10.1002/ppul.25930. PMID: 35510654
Le Caer H, Teissier E, Barriere JR, Venissac N
Crit Rev Oncol Hematol 2018 May;125:48-50. Epub 2018 Mar 3 doi: 10.1016/j.critrevonc.2018.02.009. PMID: 29650276
Puligandla PS, Laberge JM
Clin Perinatol 2012 Jun;39(2):331-47. doi: 10.1016/j.clp.2012.04.009. PMID: 22682383
Prasad A, Choudhry P, Sarin YK, Saran RK
Indian J Pediatr 2001 Aug;68(8):793-6. doi: 10.1007/BF02752427. PMID: 11563261

Prognosis

Wang F, Zhuang L, Liang J, Li L, Wang H, Tang J, Zeng J, Liu W
Pediatr Pulmonol 2022 Sep;57(9):2237-2243. Epub 2022 Jun 13 doi: 10.1002/ppul.25930. PMID: 35510654
González IA, Stewart DR, Schultz KAP, Field AP, Hill DA, Dehner LP
Mod Pathol 2022 Jan;35(1):4-22. Epub 2021 Oct 1 doi: 10.1038/s41379-021-00905-8. PMID: 34599283Free PMC Article
Weissferdt A, Moran CA
Adv Anat Pathol 2011 May;18(3):179-89. doi: 10.1097/PAP.0b013e318216980c. PMID: 21490435
Koss MN, Hochholzer L, O'Leary T
Cancer 1991 May 1;67(9):2368-81. doi: 10.1002/1097-0142(19910501)67:9<2368::aid-cncr2820670926>3.0.co;2-g. PMID: 1849449
Peacock MJ, Whitwell F
Thorax 1976 Apr;31(2):197-204. doi: 10.1136/thx.31.2.197. PMID: 941110Free PMC Article

Clinical prediction guides

Dehner LP, Schultz KAP, Hill DA
Pediatr Dev Pathol 2023 May-Jun;26(3):241-249. Epub 2023 Feb 21 doi: 10.1177/10935266221146823. PMID: 37334833
Kunisaki SM, Lal DR, Saito JM, Fallat ME, St Peter SD, Fox ZD, Heider A, Chan SS, Boyd KP, Burns RC, Deans KJ, Gadepalli SK, Hirschl RB, Kabre R, Landman MP, Leys CM, Mak GZ, Minneci PC, Wright TN, Helmrath MA; MIDWEST PEDIATRIC SURGERY CONSORTIUM
Pediatrics 2021 Apr;147(4) Epub 2021 Mar 24 doi: 10.1542/peds.2020-028357. PMID: 33762310
Bu X, Liu J, Wei L, Wang X, Chen M
BMC Cancer 2020 Aug 26;20(1):811. doi: 10.1186/s12885-020-07323-0. PMID: 32847556Free PMC Article
Koss MN, Hochholzer L, O'Leary T
Cancer 1991 May 1;67(9):2368-81. doi: 10.1002/1097-0142(19910501)67:9<2368::aid-cncr2820670926>3.0.co;2-g. PMID: 1849449
Manivel JC, Priest JR, Watterson J, Steiner M, Woods WG, Wick MR, Dehner LP
Cancer 1988 Oct 15;62(8):1516-26. doi: 10.1002/1097-0142(19881015)62:8<1516::aid-cncr2820620812>3.0.co;2-3. PMID: 3048630

Recent systematic reviews

Cai S, Zhao W, Nie X, Abbas A, Fu L, Bihi S, Feng G, Liu T, Lv Y, Ma X, Peng X
J Pediatr Hematol Oncol 2017 Jul;39(5):355-361. doi: 10.1097/MPH.0000000000000715. PMID: 27906793

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...