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Specific language impairment

MedGen UID:
627772
Concept ID:
C0454651
Disease or Syndrome
Synonyms: Disorder, Specific Language; Disorders, Specific Language; Impairment, Specific Language; Impairments, Specific Language; Language Disorder, Specific; Language Disorders, Specific; Language Impairment, Specific; Language Impairments, Specific; Specific Language Disorder; Specific Language Disorders; Specific Language Impairment; Specific Language Impairments
SNOMED CT: Specific language disorder (229746007); Specific language impairment (229746007)
 
Monarch Initiative: MONDO:0000724
OMIM® Phenotypic series: PS606711
Orphanet: ORPHA458713

Definition

A language disorder characterized by difficulty in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSpecific language impairment

Professional guidelines

PubMed

Leonard LB, Kueser JB
Int J Lang Commun Disord 2019 May;54(3):347-361. Epub 2019 Feb 7 doi: 10.1111/1460-6984.12456. PMID: 30729604Free PMC Article
Montgomery JW, Magimairaj BM, Finney MC
Am J Speech Lang Pathol 2010 Feb;19(1):78-94. Epub 2009 Nov 30 doi: 10.1044/1058-0360(2009/09-0028). PMID: 19948760
Bishop DV, Hayiou-Thomas ME
Genes Brain Behav 2008 Apr;7(3):365-72. Epub 2007 Oct 4 doi: 10.1111/j.1601-183X.2007.00360.x. PMID: 17919296Free PMC Article

Recent clinical studies

Etiology

Rice ML
J Speech Lang Hear Res 2020 Oct 16;63(10):3219-3223. doi: 10.1044/2020_JSLHR-20-00504. PMID: 33064602Free PMC Article
Spanoudis GC, Papadopoulos TC, Spyrou S
J Learn Disabil 2019 Jan/Feb;52(1):3-14. Epub 2018 May 23 doi: 10.1177/0022219418775111. PMID: 29790413
Pedott PR, Cáceres-Assenço AM, Befi-Lopes DM
Codas 2017 Mar 30;29(2):e20160017. doi: 10.1590/2317-1782/20172016017. PMID: 28380200
Schiff R, Nuri Ben-Shushan Y, Ben-Artzi E
J Learn Disabil 2017 Mar/Apr;50(2):143-157. Epub 2016 Aug 4 doi: 10.1177/0022219415589847. PMID: 26054726
Spanoudis G
J Commun Disord 2016 May-Jun;61:83-96. Epub 2016 Apr 11 doi: 10.1016/j.jcomdis.2016.04.003. PMID: 27089201

Diagnosis

Paul R
Handb Clin Neurol 2020;174:21-35. doi: 10.1016/B978-0-444-64148-9.00002-8. PMID: 32977879
Bishop DVM, Snowling MJ, Thompson PA, Greenhalgh T; and the CATALISE-2 consortium
J Child Psychol Psychiatry 2017 Oct;58(10):1068-1080. Epub 2017 Mar 30 doi: 10.1111/jcpp.12721. PMID: 28369935Free PMC Article
Kirby A, Sugden D, Purcell C
Arch Dis Child 2014 Mar;99(3):292-6. Epub 2013 Nov 19 doi: 10.1136/archdischild-2012-303569. PMID: 24255567
Kamhi AG, Clark MK
Handb Clin Neurol 2013;111:219-27. doi: 10.1016/B978-0-444-52891-9.00022-1. PMID: 23622167
Bishop DV
Philos Trans R Soc Lond B Biol Sci 1994 Oct 29;346(1315):105-11. doi: 10.1098/rstb.1994.0134. PMID: 7886145

Therapy

Larson C, Gangopadhyay I, Kaushanskaya M, Weismer SE
J Speech Lang Hear Res 2019 Aug 15;62(8):2772-2784. Epub 2019 Jul 24 doi: 10.1044/2019_JSLHR-L-18-0367. PMID: 31343936Free PMC Article
Pavelko SL, Lieberman RJ, Schwartz J, Hahs-Vaughn D, Nye C
Clin Linguist Phon 2017;31(7-9):682-696. Epub 2017 May 8 doi: 10.1080/02699206.2017.1310298. PMID: 28481668
Kasper J, Kreis J, Scheibler F, Möller D, Skipka G, Lange S, von dem Knesebeck O
Folia Phoniatr Logop 2011;63(5):247-63. Epub 2011 Feb 8 doi: 10.1159/000321000. PMID: 21304231
Redmond SM, Thompson HL, Goldstein S
J Speech Lang Hear Res 2011 Feb;54(1):99-117. Epub 2010 Aug 18 doi: 10.1044/1092-4388(2010/10-0010). PMID: 20719871Free PMC Article
Bishop DV
Philos Trans R Soc Lond B Biol Sci 1994 Oct 29;346(1315):105-11. doi: 10.1098/rstb.1994.0134. PMID: 7886145

Prognosis

Bogaerts L, Siegelman N, Frost R
Perspect Psychol Sci 2021 Mar;16(2):319-337. Epub 2020 Nov 2 doi: 10.1177/1745691620953082. PMID: 33136519Free PMC Article
Bishop DVM, Snowling MJ, Thompson PA, Greenhalgh T; and the CATALISE-2 consortium
J Child Psychol Psychiatry 2017 Oct;58(10):1068-1080. Epub 2017 Mar 30 doi: 10.1111/jcpp.12721. PMID: 28369935Free PMC Article
Spanoudis G
J Commun Disord 2016 May-Jun;61:83-96. Epub 2016 Apr 11 doi: 10.1016/j.jcomdis.2016.04.003. PMID: 27089201
Moyle J, Stokes SF, Klee T
Dev Disabil Res Rev 2011;17(2):160-9. doi: 10.1002/ddrr.1110. PMID: 23362035
Mills DL, Neville HJ
Semin Pediatr Neurol 1997 Jun;4(2):125-34. doi: 10.1016/s1071-9091(97)80029-0. PMID: 9195670

Clinical prediction guides

Bogaerts L, Siegelman N, Frost R
Perspect Psychol Sci 2021 Mar;16(2):319-337. Epub 2020 Nov 2 doi: 10.1177/1745691620953082. PMID: 33136519Free PMC Article
Spanoudis GC, Papadopoulos TC, Spyrou S
J Learn Disabil 2019 Jan/Feb;52(1):3-14. Epub 2018 May 23 doi: 10.1177/0022219418775111. PMID: 29790413
Moyle J, Stokes SF, Klee T
Dev Disabil Res Rev 2011;17(2):160-9. doi: 10.1002/ddrr.1110. PMID: 23362035
Mills DL, Neville HJ
Semin Pediatr Neurol 1997 Jun;4(2):125-34. doi: 10.1016/s1071-9091(97)80029-0. PMID: 9195670
Martins IP
Clin Neurosci 1997;4(2):73-7. PMID: 9059756

Recent systematic reviews

Pulliam G, Feldman JI, Woynaroski TG
Neurosci Biobehav Rev 2023 Jun;149:105130. Epub 2023 Mar 17 doi: 10.1016/j.neubiorev.2023.105130. PMID: 36933815Free PMC Article
Zwart FS, Vissers CTWM, Kessels RPC, Maes JHR
J Neuropsychol 2019 Jun;13(2):149-182. Epub 2017 Oct 8 doi: 10.1111/jnp.12139. PMID: 28990357
Rudolph JM
Am J Speech Lang Pathol 2017 Aug 15;26(3):991-1010. doi: 10.1044/2016_AJSLP-15-0181. PMID: 28672377
Nilsson KK, de López KJ
Child Dev 2016 Jan-Feb;87(1):143-53. Epub 2015 Nov 19 doi: 10.1111/cdev.12462. PMID: 26582261
Kasper J, Kreis J, Scheibler F, Möller D, Skipka G, Lange S, von dem Knesebeck O
Folia Phoniatr Logop 2011;63(5):247-63. Epub 2011 Feb 8 doi: 10.1159/000321000. PMID: 21304231

Supplemental Content

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