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Lytic Bone Lesion

MedGen UID:
67445
•Concept ID:
C0221204
•
Finding; Pathologic Function
Synonym: Lytic lesions

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLytic Bone Lesion

Professional guidelines

PubMed

Interventional radiology for treatment of bone metastases.
Hayek G, Kastler B
Cancer Radiother 2020 Aug;24(5):374-378. Epub 2020 Jun 8 doi: 10.1016/j.canrad.2020.04.006. PMID: 32527694
Primary Osteosarcoma in the Elderly Revisited: Current Concepts in Diagnosis and Treatment.
Kumar R, Kumar M, Malhotra K, Patel S
Curr Oncol Rep 2018 Feb 28;20(2):13. doi: 10.1007/s11912-018-0658-1. PMID: 29492676
Treatment of multifocal lymphoma of bone with intensified ProMACE-CytaBOM chemotherapy and involved field radiotherapy.
Rapoport AP, Constine LS, Packman CH, Rosier RN, O'Keefe R, Hicks DG, Rubin SJ, Rowe JM
Am J Hematol 1998 May;58(1):1-7. doi: 10.1002/(sici)1096-8652(199805)58:1<1::aid-ajh1>3.0.co;2-x. PMID: 9590141

Recent clinical studies

Etiology

Interventional radiology for treatment of bone metastases.
Hayek G, Kastler B
Cancer Radiother 2020 Aug;24(5):374-378. Epub 2020 Jun 8 doi: 10.1016/j.canrad.2020.04.006. PMID: 32527694
Childhood Langerhans cell histiocytosis: a disease with many faces.
Leung AKC, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):536-545. Epub 2019 Aug 28 doi: 10.1007/s12519-019-00304-9. PMID: 31456157
Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial.
Tripathy D, Im SA, Colleoni M, Franke F, Bardia A, Harbeck N, Hurvitz SA, Chow L, Sohn J, Lee KS, Campos-Gomez S, Villanueva Vazquez R, Jung KH, Babu KG, Wheatley-Price P, De Laurentiis M, Im YH, Kuemmel S, El-Saghir N, Liu MC, Carlson G, Hughes G, Diaz-Padilla I, Germa C, Hirawat S, Lu YS
Lancet Oncol 2018 Jul;19(7):904-915. Epub 2018 May 24 doi: 10.1016/S1470-2045(18)30292-4. PMID: 29804902
Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study.
Raje N, Terpos E, Willenbacher W, Shimizu K, García-Sanz R, Durie B, Legieć W, Krejčí M, Laribi K, Zhu L, Cheng P, Warner D, Roodman GD
Lancet Oncol 2018 Mar;19(3):370-381. Epub 2018 Feb 9 doi: 10.1016/S1470-2045(18)30072-X. PMID: 29429912
Bisphosphonates and breast carcinoma.
Lipton A
Cancer 1997 Oct 15;80(8 Suppl):1668-73. doi: 10.1002/(sici)1097-0142(19971015)80:8+<1668::aid-cncr17>3.3.co;2-5. PMID: 9362434

Diagnosis

Childhood Langerhans cell histiocytosis: a disease with many faces.
Leung AKC, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):536-545. Epub 2019 Aug 28 doi: 10.1007/s12519-019-00304-9. PMID: 31456157
Salmonella Osteomyelitis Of Ribs.
Khan I, Mufti AJ, Khan MM, Khan A, Afridi H, Jan H
J Ayub Med Coll Abbottabad 2018 Oct-Dec;30(4):605-607. PMID: 30632347
Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study.
Raje N, Terpos E, Willenbacher W, Shimizu K, García-Sanz R, Durie B, Legieć W, Krejčí M, Laribi K, Zhu L, Cheng P, Warner D, Roodman GD
Lancet Oncol 2018 Mar;19(3):370-381. Epub 2018 Feb 9 doi: 10.1016/S1470-2045(18)30072-X. PMID: 29429912
Isolated lytic bone lesion in tuberculosis.
Abdulla MC
Int J Mycobacteriol 2017 Apr-Jun;6(2):191-192. doi: 10.4103/ijmy.ijmy_62_17. PMID: 28559524
Lymphangiomatosis with dental involvement.
Findler M, Hirshberg A, Sharon E
Lymphat Res Biol 2015 Mar;13(1):62-5. Epub 2014 Sep 5 doi: 10.1089/lrb.2013.0040. PMID: 25192473

Therapy

Interventional radiology for treatment of bone metastases.
Hayek G, Kastler B
Cancer Radiother 2020 Aug;24(5):374-378. Epub 2020 Jun 8 doi: 10.1016/j.canrad.2020.04.006. PMID: 32527694
Childhood Langerhans cell histiocytosis: a disease with many faces.
Leung AKC, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):536-545. Epub 2019 Aug 28 doi: 10.1007/s12519-019-00304-9. PMID: 31456157
Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial.
Tripathy D, Im SA, Colleoni M, Franke F, Bardia A, Harbeck N, Hurvitz SA, Chow L, Sohn J, Lee KS, Campos-Gomez S, Villanueva Vazquez R, Jung KH, Babu KG, Wheatley-Price P, De Laurentiis M, Im YH, Kuemmel S, El-Saghir N, Liu MC, Carlson G, Hughes G, Diaz-Padilla I, Germa C, Hirawat S, Lu YS
Lancet Oncol 2018 Jul;19(7):904-915. Epub 2018 May 24 doi: 10.1016/S1470-2045(18)30292-4. PMID: 29804902
Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study.
Raje N, Terpos E, Willenbacher W, Shimizu K, García-Sanz R, Durie B, Legieć W, Krejčí M, Laribi K, Zhu L, Cheng P, Warner D, Roodman GD
Lancet Oncol 2018 Mar;19(3):370-381. Epub 2018 Feb 9 doi: 10.1016/S1470-2045(18)30072-X. PMID: 29429912
Bisphosphonates and breast carcinoma.
Lipton A
Cancer 1997 Oct 15;80(8 Suppl):1668-73. doi: 10.1002/(sici)1097-0142(19971015)80:8+<1668::aid-cncr17>3.3.co;2-5. PMID: 9362434

Prognosis

Diffuse large B cell lymphoma presenting with renal failure and bone lesions in a 46-year-old woman: a case report and review of literature.
Ben Abdelghani K, Rouached L, Mourad Dali K, Fazaa A, Miladi S, Sellami M, Ouenniche K, Souabni L, Kassab S, Chekili S, Laatar A
CEN Case Rep 2021 May;10(2):165-171. Epub 2020 Sep 28 doi: 10.1007/s13730-020-00537-y. PMID: 32989684Free PMC Article
Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial.
Tripathy D, Im SA, Colleoni M, Franke F, Bardia A, Harbeck N, Hurvitz SA, Chow L, Sohn J, Lee KS, Campos-Gomez S, Villanueva Vazquez R, Jung KH, Babu KG, Wheatley-Price P, De Laurentiis M, Im YH, Kuemmel S, El-Saghir N, Liu MC, Carlson G, Hughes G, Diaz-Padilla I, Germa C, Hirawat S, Lu YS
Lancet Oncol 2018 Jul;19(7):904-915. Epub 2018 May 24 doi: 10.1016/S1470-2045(18)30292-4. PMID: 29804902
Primary Osteosarcoma in the Elderly Revisited: Current Concepts in Diagnosis and Treatment.
Kumar R, Kumar M, Malhotra K, Patel S
Curr Oncol Rep 2018 Feb 28;20(2):13. doi: 10.1007/s11912-018-0658-1. PMID: 29492676
Primary adult T cell leukemia of bone: two patients with primary bone lesion showing monoclonal integration of HTLV-I proviral DNA.
Takemoto S, Matsuoka M, Sakata K, Matsuzaki H, Akagi K, Yamaguchi K, Takatsuki K
Leukemia 1996 Feb;10(2):333-7. PMID: 8637243
Pathological fractures and lytic bone lesion of the femoral neck associated with beta 2-microglobulin amyloid deposition in long-term dialysis patients.
Scheumann GF, Holch M, Nerlich ML, Brandis A, Ostertag H, Tscherne H
Arch Orthop Trauma Surg 1991;110(2):93-7. doi: 10.1007/BF00393881. PMID: 2015141

Clinical prediction guides

Childhood Langerhans cell histiocytosis: a disease with many faces.
Leung AKC, Lam JM, Leong KF
World J Pediatr 2019 Dec;15(6):536-545. Epub 2019 Aug 28 doi: 10.1007/s12519-019-00304-9. PMID: 31456157
Clinical factors affecting pathological fracture and healing of unicameral bone cysts.
Urakawa H, Tsukushi S, Hosono K, Sugiura H, Yamada K, Yamada Y, Kozawa E, Arai E, Futamura N, Ishiguro N, Nishida Y
BMC Musculoskelet Disord 2014 May 17;15:159. doi: 10.1186/1471-2474-15-159. PMID: 24884661Free PMC Article
The assessment of round lytic lesions in sternotomies.
Giassi KS, Correa MF, Fujita CL, Cerri GG, Leite CC
Br J Radiol 2014 Jan;87(1033):20130342. Epub 2013 Dec 2 doi: 10.1259/bjr.20130342. PMID: 24297810Free PMC Article
Bone marrow edema pattern identification in patients with lytic bone lesions using digital subtraction angiography-like bone subtraction on large-area detector computed tomography.
Gondim Teixeira PA, Hossu G, Lecocq S, Razeto M, Louis M, Blum A
Invest Radiol 2014 Mar;49(3):156-64. doi: 10.1097/RLI.0000000000000007. PMID: 24220254
Bisphosphonates and breast carcinoma.
Lipton A
Cancer 1997 Oct 15;80(8 Suppl):1668-73. doi: 10.1002/(sici)1097-0142(19971015)80:8+<1668::aid-cncr17>3.3.co;2-5. PMID: 9362434

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