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Chronic discoid lupus erythematosus

MedGen UID:
7402
Concept ID:
C0024138
Disease or Syndrome
Synonyms: Discoid Lupus Erythematosus; Lupus Erythematosus, Chronic Cutaneous; Lupus Erythematosus, Cutaneous, Chronic; Lupus Erythematosus, Discoid
SNOMED CT: CDLE - Chronic discoid lupus erythematosus (238927000); Chronic discoid lupus erythematosus (238927000)

Definition

A chronic, autoimmune skin condition that manifests with a red, scaling rash, most often found on the face, ears, and scalp; these lesions often lead to permanent scarring and dyspigmentation. Patients may have lesions with or without other symptoms or antibodies suggestive of systemic lupus erythematosus (SLE). [from NCI]

Professional guidelines

PubMed

Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Knop J, Bonsmann G, Happle R, Ludolph A, Matz DR, Mifsud EJ, Macher E
Br J Dermatol 1983 Apr;108(4):461-6. doi: 10.1111/j.1365-2133.1983.tb04600.x. PMID: 6838771
GOLDMAN L
J Invest Dermatol 1948 Aug;11(2):95. doi: 10.1038/jid.1948.74. PMID: 18877035

Recent clinical studies

Etiology

Kluger N, Andraud M, Lartigau-Roussin C, Sultan-Bichat N
Acta Dermatovenerol Alp Pannonica Adriat 2021 Mar;30(1):43-46. PMID: 33765758
Gao X, Ma L, Zhou Z, Jian X, Liu W
Int J Surg Pathol 2016 Oct;24(7):595-9. Epub 2016 May 29 doi: 10.1177/1066896916652220. PMID: 27240861
Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Shahidullah M, Lee YS, Khor CJ, Ratnam KV
Ann Acad Med Singap 1995 Nov;24(6):789-92. PMID: 8838982
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993

Diagnosis

Satta R, Marongiu P, Cottoni F
G Ital Dermatol Venereol 2016 Apr;151(2):203-5. PMID: 27068596
Pramatarov KD
Clin Dermatol 2004 Mar-Apr;22(2):113-20. doi: 10.1016/j.clindermatol.2003.12.016. PMID: 15234011
Kulthanan K, Roongphiboolsopit P, Chanjanakijskul S, Kullavanijaya P
Int J Dermatol 1996 Oct;35(10):711-4. doi: 10.1111/j.1365-4362.1996.tb00643.x. PMID: 8891819
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
ROTHFIELD N, MARCH CH, MIESCHER P, MCEWEN C
N Engl J Med 1963 Nov 28;269:1155-61. doi: 10.1056/NEJM196311282692201. PMID: 14061123

Therapy

Jin X, Lu S, Xing X, Wang L, Mu D, He M, Huang H, Zeng X, Chen Q
J Oral Pathol Med 2013 May;42(5):355-62. Epub 2012 Sep 17 doi: 10.1111/jop.12004. PMID: 22978368
Erceg A, Bovenschen HJ, van de Kerkhof PC, de Jong EM, Seyger MM
J Am Acad Dermatol 2009 Apr;60(4):626-32. doi: 10.1016/j.jaad.2008.11.904. PMID: 19293010
Perri AJ 3rd, Hsu S
Dermatol Online J 2003 Aug;9(3):5. PMID: 12952752
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253
Winkelmann RK
JAMA 1968 Sep 2;205(10):675-8. PMID: 5695138

Prognosis

Dadlani C, Pulitzer M, Prystowsky SD
Dermatol Online J 2008 May 15;14(5):5. PMID: 18627741
Kyriakis KP, Kontochristopoulos GJ, Panteleos DN
Int J Dermatol 2000 Mar;39(3):218-22. doi: 10.1046/j.1365-4362.2000.00953.x. PMID: 10759967
Halder RM, Bridgeman-Shah S
Cancer 1995 Jan 15;75(2 Suppl):667-73. doi: 10.1002/1097-0142(19950115)75:2+<667::aid-cncr2820751409>3.0.co;2-i. PMID: 7804993
Knop J, Bonsmann G, Happle R, Ludolph A, Matz DR, Mifsud EJ, Macher E
Br J Dermatol 1983 Apr;108(4):461-6. doi: 10.1111/j.1365-2133.1983.tb04600.x. PMID: 6838771
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253

Clinical prediction guides

Weiss A, Kwon EJ, Kreidel M, Mann R, Cohen JA, Hui Y, Jacobson MI
Am J Dermatopathol 2020 Feb;42(2):129-132. doi: 10.1097/DAD.0000000000001510. PMID: 31464721
Satta R, Marongiu P, Cottoni F
G Ital Dermatol Venereol 2016 Apr;151(2):203-5. PMID: 27068596
Erceg A, De Jong EM, Van Lingen RG, De Boo TM, Van De Kerkhof PC, Seyger MM
J Dermatolog Treat 2009;20(1):32-5. doi: 10.1080/09546630802155040. PMID: 18608708
Kulthanan K, Roongphiboolsopit P, Chanjanakijskul S, Kullavanijaya P
Int J Dermatol 1996 Oct;35(10):711-4. doi: 10.1111/j.1365-4362.1996.tb00643.x. PMID: 8891819
Callen JP
Arch Dermatol 1982 Jun;118(6):412-6. doi: 10.1001/archderm.118.6.412. PMID: 7092253

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