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Mediastinal shift

MedGen UID:: 75541
•Concept ID:: C0264576
•: Finding

Synonym:	Mediastinal Shift
SNOMED CT:	Mediastinal shift (19616004)

HPO:	HP:6000012

Definition

A deviation of the mediastinum from its normal position in the midline of the thoracic cavity. The mediastinum is a compartment of the thoracic cavity that contains the heart and its blood vessels, the esophagus, trachea, thymus, as well as nerves and lymph nodes. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMediastinal shift

Phenotypic abnormality
- Abnormality of the thoracic cavity
  - Abnormal mediastinum morphology
    - Mediastinal shift

Professional guidelines

PubMed

A clinical guideline for structured assessment of CT-imaging in congenital lung abnormalities.

Hermelijn SM, Elders BBLJ, Ciet P, Wijnen RMH, Tiddens HAWM, Schnater JM
Paediatr Respir Rev 2021 Mar;37:80-88. Epub 2020 Feb 20 doi: 10.1016/j.prrv.2019.12.004. PMID: 32178987

Emergency Management of Acute Late-Presenting Congenital Diaphragmatic Hernia in Infants and Children.

Yuan M, Li F, Xu C, Fan X, Yang G, Xiang B, Huang L
Pediatr Emerg Care 2021 Jul 1;37(7):357-359. doi: 10.1097/PEC.0000000000001860. PMID: 31219969 Free PMC Article

Fetal primary pleural effusions: Prenatal diagnosis and management.

Abbasi N, Ryan G
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:66-77. Epub 2019 Jan 12 doi: 10.1016/j.bpobgyn.2019.01.005. PMID: 30737016

See all (29)

Recent clinical studies

Etiology

Fetal MRI mediastinal shift angle and respiratory and cardiovascular pharmacological support in newborns with congenital diaphragmatic hernia.

Amodeo I, Borzani I, Corsani G, Pesenti N, Raffaeli G, Macchini F, Condò V, Persico N, Ghirardello S, Colnaghi M, Mosca F, Cavallaro G
Eur J Pediatr 2022 Jan;181(1):323-334. Epub 2021 Jul 23 doi: 10.1007/s00431-021-04207-8. PMID: 34302257

Fetal primary pleural effusions: Prenatal diagnosis and management.

Abbasi N, Ryan G
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:66-77. Epub 2019 Jan 12 doi: 10.1016/j.bpobgyn.2019.01.005. PMID: 30737016

Acute Respiratory Distress in Children: Croup and Acute Asthma.

Sharma BS, Shekhawat DS, Sharma P, Meena C, Mohan H
Indian J Pediatr 2015 Jul;82(7):629-36. Epub 2014 Sep 26 doi: 10.1007/s12098-014-1559-4. PMID: 25257964

Is it safe not to drain the pneumonectomy space?

Morcos K, Shaikhrezai K, Kirk AJ
Interact Cardiovasc Thorac Surg 2014 May;18(5):671-5. Epub 2014 Jan 30 doi: 10.1093/icvts/ivt563. PMID: 24480821

Atelectasis in children.

Raman TS, Mathew S, Ravikumar, Garcha PS
Indian Pediatr 1998 May;35(5):429-35. PMID: 10216624

See all (162)

Diagnosis

Comparison of mediastinal shift angles obtained with ultrasound and magnetic resonance imaging in fetuses with isolated left sided congenital diaphragmatic hernia.

Romiti A, Viggiano M, Savelli S, Salvi S, Vicario R, Vassallo C, Valfrè L, Tomà P, Bonito M, Lanzone A, Bagolan P, Caforio L
J Matern Fetal Neonatal Med 2022 Jan;35(2):269-274. Epub 2020 Jan 23 doi: 10.1080/14767058.2020.1716714. PMID: 31973612

Fetal primary pleural effusions: Prenatal diagnosis and management.

Abbasi N, Ryan G
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:66-77. Epub 2019 Jan 12 doi: 10.1016/j.bpobgyn.2019.01.005. PMID: 30737016

Pulmonary Agenesis.

Chawla RK, Madan A, Chawla A, Arora HN, Chawla K
Indian J Chest Dis Allied Sci 2015 Oct-Dec;57(4):251-3. PMID: 27164736

Management of congenital lung lesions.

Stanton M, Davenport M
Early Hum Dev 2006 May;82(5):289-95. Epub 2006 Apr 3 doi: 10.1016/j.earlhumdev.2006.02.006. PMID: 16581208

Atelectasis in children.

Raman TS, Mathew S, Ravikumar, Garcha PS
Indian Pediatr 1998 May;35(5):429-35. PMID: 10216624

See all (263)

Therapy

Fetal MRI mediastinal shift angle and respiratory and cardiovascular pharmacological support in newborns with congenital diaphragmatic hernia.

Fetal primary pleural effusions: Prenatal diagnosis and management.

Abbasi N, Ryan G
Best Pract Res Clin Obstet Gynaecol 2019 Jul;58:66-77. Epub 2019 Jan 12 doi: 10.1016/j.bpobgyn.2019.01.005. PMID: 30737016

Is it safe not to drain the pneumonectomy space?

Morcos K, Shaikhrezai K, Kirk AJ
Interact Cardiovasc Thorac Surg 2014 May;18(5):671-5. Epub 2014 Jan 30 doi: 10.1093/icvts/ivt563. PMID: 24480821

In utero therapy for fetal thoracic abnormalities.

Wilson RD
Prenat Diagn 2008 Jul;28(7):619-25. doi: 10.1002/pd.1968. PMID: 18634114

Postpneumonectomy chylothorax.

Sarsam MA, Rahman AN, Deiraniya AK
Ann Thorac Surg 1994 Mar;57(3):689-90. doi: 10.1016/0003-4975(94)90568-1. PMID: 8147641

See all (97)

Prognosis

Thoracic mediastinal-occupying ratio predicts recovery and prognosis after lung transplantation.

Yoshiyasu N, Sato M, Yasui T, Takami M, Kawahara T, Konoeda C, Nakajima J
Interact Cardiovasc Thorac Surg 2022 Aug 3;35(3) doi: 10.1093/icvts/ivac106. PMID: 35445700 Free PMC Article

Fetal MRI mediastinal shift angle and respiratory and cardiovascular pharmacological support in newborns with congenital diaphragmatic hernia.

Pulmonary Agenesis.

Chawla RK, Madan A, Chawla A, Arora HN, Chawla K
Indian J Chest Dis Allied Sci 2015 Oct-Dec;57(4):251-3. PMID: 27164736

Fetal pleural effusions.

Yinon Y, Kelly E, Ryan G
Best Pract Res Clin Obstet Gynaecol 2008 Feb;22(1):77-96. doi: 10.1016/j.bpobgyn.2007.09.004. PMID: 18280793

Postpneumonectomy chylothorax.

Sarsam MA, Rahman AN, Deiraniya AK
Ann Thorac Surg 1994 Mar;57(3):689-90. doi: 10.1016/0003-4975(94)90568-1. PMID: 8147641

See all (147)

Clinical prediction guides

Reversible platypnoea-orthodeoxia syndrome.

Joseph TJ, Isaac BT, James P, Thangakunam B
BMJ Case Rep 2023 Oct 31;16(10) doi: 10.1136/bcr-2023-255587. PMID: 37907322 Free PMC Article

Mediastinal shift angle (MSA) measurement with MRI: a simple and effective tool for prenatal risk stratification in fetuses with congenital diaphragmatic hernia.

Ding W, Gu Y, Wu H, Wang H, Zhang X, Wang H, Huang L, Zhang R, He Q, Zhong W, Lv J, Xia B, Zhang G, Mei S
Eur Radiol 2023 Mar;33(3):1668-1676. Epub 2022 Sep 30 doi: 10.1007/s00330-022-09142-2. PMID: 36180644

Thoracic mediastinal-occupying ratio predicts recovery and prognosis after lung transplantation.

Yoshiyasu N, Sato M, Yasui T, Takami M, Kawahara T, Konoeda C, Nakajima J
Interact Cardiovasc Thorac Surg 2022 Aug 3;35(3) doi: 10.1093/icvts/ivac106. PMID: 35445700 Free PMC Article

Fetal MRI mediastinal shift angle and respiratory and cardiovascular pharmacological support in newborns with congenital diaphragmatic hernia.

Comparison of mediastinal shift angles obtained with ultrasound and magnetic resonance imaging in fetuses with isolated left sided congenital diaphragmatic hernia.

See all (101)