U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Hyperproteinemia

MedGen UID:
75648
•Concept ID:
C0267988
•
Disease or Syndrome; Finding
SNOMED CT: Hyperproteinemia (37064009)
 
HPO: HP:0002152

Definition

An increased concentration of proteins in the blood. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperproteinemia

Professional guidelines

PubMed

Laboratory reflex testing strategy for the early identification of primary care patients with multiple myeloma.
Salinas M, Flores E, Blasco A, Lopez-Garrigós M, Torreblanca R, Leiva-Salinas M, Gutierrez I, Leiva-Salinas C; PRIMary Care-LABoratory (PRIMLAB) working group
Clin Biochem 2024 Apr;126:110730. Epub 2024 Feb 21 doi: 10.1016/j.clinbiochem.2024.110730. PMID: 38387751
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
Diagnosis, pathophysiology, and treatment of chronic twin-to-twin transfusion syndrome.
Weiner CP, Ludomirski A
Fetal Diagn Ther 1994 Sep-Oct;9(5):283-90. doi: 10.1159/000263949. PMID: 7818775

Recent clinical studies

Etiology

Associations between presence of Bartonella species deoxyribonucleic acid and complete blood cell count and serum biochemical changes in client-owned cats.
Williams M, Rao S, Braff J, Buch JS, Chandrashekar R, Lappin MR
J Vet Intern Med 2022 Mar;36(2):532-540. Epub 2022 Feb 7 doi: 10.1111/jvim.16376. PMID: 35132685Free PMC Article
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
The sand rat, Psammomys obesus, develops type 2 diabetic retinopathy similar to humans.
Saïdi T, Mbarek S, Omri S, Behar-Cohen F, Chaouacha-Chekir RB, Hicks D
Invest Ophthalmol Vis Sci 2011 Nov 21;52(12):8993-9004. doi: 10.1167/iovs.11-8423. PMID: 21989730
Pediatric visceral Leishmaniasis in Turkey.
Tanir G, Taylan Ozkan A, Dağlar E
Pediatr Int 2006 Feb;48(1):66-9. doi: 10.1111/j.1442-200X.2006.02153.x. PMID: 16490074
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010

Diagnosis

Associations between presence of Bartonella species deoxyribonucleic acid and complete blood cell count and serum biochemical changes in client-owned cats.
Williams M, Rao S, Braff J, Buch JS, Chandrashekar R, Lappin MR
J Vet Intern Med 2022 Mar;36(2):532-540. Epub 2022 Feb 7 doi: 10.1111/jvim.16376. PMID: 35132685Free PMC Article
A uterine pseudotumor of immunoglobulin G4-related disease.
Senda Y, Ikeda Y, Tamauchi S, Yoshikawa N, Kikkawa F, Kajiyama H
J Obstet Gynaecol Res 2021 Jan;47(1):430-435. Epub 2020 Oct 15 doi: 10.1111/jog.14531. PMID: 33059388
Hyponatremia.
DiBartola SP
Vet Clin North Am Small Anim Pract 1998 May;28(3):515-32. doi: 10.1016/s0195-5616(98)50053-8. PMID: 9597712
Assessment of hypocalcemia and hypercalcemia.
Bourke E, Delaney V
Clin Lab Med 1993 Mar;13(1):157-81. PMID: 8462259
Pseudohyponatremia.
Aw TC, Kiechle FL
Am J Emerg Med 1985 May;3(3):236-9. doi: 10.1016/0735-6757(85)90096-8. PMID: 3994801

Therapy

Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
Electrolytes: Sodium Disorders.
Braun MM, Mahowald M
FP Essent 2017 Aug;459:11-20. PMID: 28806046
IgG4-unrelated type 1 autoimmune pancreatitis.
Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa T
World J Gastroenterol 2015 Sep 7;21(33):9808-16. doi: 10.3748/wjg.v21.i33.9808. PMID: 26361429Free PMC Article
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010
Gram-negative meningitis associated with transsphenoidal surgery: case reports and review.
Haile-Mariam T, Laws E, Tuazon CU
Clin Infect Dis 1994 Apr;18(4):553-6. doi: 10.1093/clinids/18.4.553. PMID: 8038309

Prognosis

Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
IgG4-unrelated type 1 autoimmune pancreatitis.
Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa T
World J Gastroenterol 2015 Sep 7;21(33):9808-16. doi: 10.3748/wjg.v21.i33.9808. PMID: 26361429Free PMC Article
Dural plasmacytoma revealing multiple myeloma. Case report.
Haegelen C, Riffaud L, Bernard M, Carsin-Nicol B, Morandi X
J Neurosurg 2006 Apr;104(4):608-10. doi: 10.3171/jns.2006.104.4.608. PMID: 16619666
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010
Seasonal variation in the incidence of hyponatremia.
Chakrapani M, Shenoy D, Pillai A
J Assoc Physicians India 2002 Apr;50:559-62. PMID: 12164409

Clinical prediction guides

Discordance of light chain isotypes between serum and glomerular deposits in proliferative glomerulonephritis with monoclonal IgG deposits: a case report and review of the literature.
Miura S, Katayama K, Sugimoto Y, Tanaka F, Mori M, Takahashi D, Saiki R, Hirabayashi Y, Murata T, Tawara I, Dohi K
BMC Nephrol 2023 Jul 1;24(1):199. doi: 10.1186/s12882-023-03256-5. PMID: 37393252Free PMC Article
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014).
Bucholz EM, Rodday AM, Kolor K, Khoury MJ, de Ferranti SD
Circulation 2018 May 22;137(21):2218-2230. Epub 2018 Mar 26 doi: 10.1161/CIRCULATIONAHA.117.032321. PMID: 29581125Free PMC Article
IgG4-unrelated type 1 autoimmune pancreatitis.
Nakano E, Kanno A, Masamune A, Yoshida N, Hongo S, Miura S, Takikawa T, Hamada S, Kume K, Kikuta K, Hirota M, Nakayama K, Fujishima F, Shimosegawa T
World J Gastroenterol 2015 Sep 7;21(33):9808-16. doi: 10.3748/wjg.v21.i33.9808. PMID: 26361429Free PMC Article
Pediatric visceral Leishmaniasis in Turkey.
Tanir G, Taylan Ozkan A, Dağlar E
Pediatr Int 2006 Feb;48(1):66-9. doi: 10.1111/j.1442-200X.2006.02153.x. PMID: 16490074
Intravenous immunoglobulin therapy results in post-infusional hyperproteinemia, increased serum viscosity, and pseudohyponatremia.
Steinberger BA, Ford SM, Coleman TA
Am J Hematol 2003 Jun;73(2):97-100. doi: 10.1002/ajh.10325. PMID: 12749010

Recent systematic reviews

Gram-negative meningitis associated with transsphenoidal surgery: case reports and review.
Haile-Mariam T, Laws E, Tuazon CU
Clin Infect Dis 1994 Apr;18(4):553-6. doi: 10.1093/clinids/18.4.553. PMID: 8038309

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...