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Orocutaneous fistula

MedGen UID:
759609
•Concept ID:
C3532496
•
Anatomical Abnormality
Synonyms: Fistula between oral cavity and cutaneous surface of face; Orocutaneous Fistula
SNOMED CT: Orocutaneous fistula (472978005); Fistula between oral cavity and cutaneous surface of face (472978005)

Definition

An abnormal communication between the skin and the oral cavity. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOrocutaneous fistula

Professional guidelines

PubMed

Chinese expert group consensus on diagnosis and clinical management of osteoradionecrosis of the mandible.
He Y, Ma C, Hou J, Li X, Peng X, Wang H, Wang S, Liu L, Liu B, Tian L, Liu Z, Liu X, Xu X, Zhang D, Jiang C, Wang J, Yao Y, Zhu G, Bai Y, Wang S, Sun C, Li J, He S, Wang C, Zhang Z, Qiu W
Int J Oral Maxillofac Surg 2020 Mar;49(3):411-419. Epub 2019 Jul 26 doi: 10.1016/j.ijom.2019.06.015. PMID: 31353174
Literature Review of Criteria for Defining Recipient-Site Infection after Oral Oncologic Surgery with Simultaneous Reconstruction.
Akashi M, Kusumoto J, Sakakibara A, Hashikawa K, Furudoi S, Komori T
Surg Infect (Larchmt) 2017 Oct;18(7):755-764. Epub 2017 Aug 9 doi: 10.1089/sur.2017.101. PMID: 28792850
The management of osteoradionecrosis of the jaws--a review.
Rice N, Polyzois I, Ekanayake K, Omer O, Stassen LF
Surgeon 2015 Apr;13(2):101-9. Epub 2014 Jul 30 doi: 10.1016/j.surge.2014.07.003. PMID: 25084627

Recent clinical studies

Etiology

Anchored sutures for fixation of the anterolateral thigh flap and prevention of orocutaneous fistula in oral and oropharyngeal cancer reconstruction.
Xin P, Huang C, Qin X, Hu C
Clin Oral Investig 2023 Nov;27(11):6537-6545. Epub 2023 Sep 18 doi: 10.1007/s00784-023-05259-w. PMID: 37718382
Orocutaneous Fistula After Oral Cavity Resection and Reconstruction: Systematic Review and Meta-Analysis.
Tassone P, Galloway T, Dooley L, Zitsch R 3rd
Ann Otol Rhinol Laryngol 2022 Aug;131(8):880-891. Epub 2021 Sep 23 doi: 10.1177/00034894211047463. PMID: 34553635
Utility of negative-pressure wound therapy for orocutaneous and pharyngocutaneous fistula following head and neck surgery.
Inatomi Y, Kadota H, Yoshida S, Kamizono K, Shimamoto R, Fukushima S, Miyashita K, Matsuo M, Yasumatsu R, Tanaka S, Fukushima J
Head Neck 2020 Jan;42(1):103-110. Epub 2019 Oct 16 doi: 10.1002/hed.25989. PMID: 31617619
Factors affecting orocutaneous fistula formation following head and neck reconstructive surgery.
Dawson C, Gadiwalla Y, Martin T, Praveen P, Parmar S
Br J Oral Maxillofac Surg 2017 Feb;55(2):132-135. Epub 2016 Aug 5 doi: 10.1016/j.bjoms.2016.07.021. PMID: 27502876
The management of osteoradionecrosis of the jaws--a review.
Rice N, Polyzois I, Ekanayake K, Omer O, Stassen LF
Surgeon 2015 Apr;13(2):101-9. Epub 2014 Jul 30 doi: 10.1016/j.surge.2014.07.003. PMID: 25084627

Diagnosis

The medial sural artery perforator flap for retromolar trigone reconstruction: A multicenter case series.
Maruccia M, Elia R, De Cosmo A, Cigna E, Tedeschi P, Bolletta A, Manrique OJ, Ciudad P, Di Summa PG, Cherubino M, Giudice G
Microsurgery 2023 Sep;43(6):546-554. Epub 2023 Feb 20 doi: 10.1002/micr.31026. PMID: 36805669
Congenital Orocutaneous Fistula Associated With Ectopic Salivary Glands and Submandibular Gland Aplasia.
Trieu V, Hosseini DK, Kim GS, Truong MT, Cheng AG
Laryngoscope 2021 Mar;131(3):E998-E1001. Epub 2020 Jul 10 doi: 10.1002/lary.28921. PMID: 33059385
Chinese expert group consensus on diagnosis and clinical management of osteoradionecrosis of the mandible.
He Y, Ma C, Hou J, Li X, Peng X, Wang H, Wang S, Liu L, Liu B, Tian L, Liu Z, Liu X, Xu X, Zhang D, Jiang C, Wang J, Yao Y, Zhu G, Bai Y, Wang S, Sun C, Li J, He S, Wang C, Zhang Z, Qiu W
Int J Oral Maxillofac Surg 2020 Mar;49(3):411-419. Epub 2019 Jul 26 doi: 10.1016/j.ijom.2019.06.015. PMID: 31353174
Squamous cell carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Robson CD, Perez-Atayde AR, Mack JW, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 Feb;117:131-137. Epub 2018 Nov 20 doi: 10.1016/j.ijporl.2018.11.019. PMID: 30579067
Literature Review of Criteria for Defining Recipient-Site Infection after Oral Oncologic Surgery with Simultaneous Reconstruction.
Akashi M, Kusumoto J, Sakakibara A, Hashikawa K, Furudoi S, Komori T
Surg Infect (Larchmt) 2017 Oct;18(7):755-764. Epub 2017 Aug 9 doi: 10.1089/sur.2017.101. PMID: 28792850

Therapy

Orocutaneous Fistula After Oral Cavity Resection and Reconstruction: Systematic Review and Meta-Analysis.
Tassone P, Galloway T, Dooley L, Zitsch R 3rd
Ann Otol Rhinol Laryngol 2022 Aug;131(8):880-891. Epub 2021 Sep 23 doi: 10.1177/00034894211047463. PMID: 34553635
Factors predisposing to the development of orocutaneous fistula following surgery for oral cancer: Experience from a tertiary cancer center.
Girkar F, Thiagarajan S, Malik A, Sawhney S, Deshmukh A, Chaukar D, D'Cruz A
Head Neck 2019 Dec;41(12):4121-4127. Epub 2019 Sep 9 doi: 10.1002/hed.25951. PMID: 31497921
Squamous cell carcinoma of the head and neck in children.
Dombrowski ND, Wolter NE, Irace AL, Robson CD, Perez-Atayde AR, Mack JW, Rahbar R
Int J Pediatr Otorhinolaryngol 2019 Feb;117:131-137. Epub 2018 Nov 20 doi: 10.1016/j.ijporl.2018.11.019. PMID: 30579067
Literature Review of Criteria for Defining Recipient-Site Infection after Oral Oncologic Surgery with Simultaneous Reconstruction.
Akashi M, Kusumoto J, Sakakibara A, Hashikawa K, Furudoi S, Komori T
Surg Infect (Larchmt) 2017 Oct;18(7):755-764. Epub 2017 Aug 9 doi: 10.1089/sur.2017.101. PMID: 28792850
The management of osteoradionecrosis of the jaws--a review.
Rice N, Polyzois I, Ekanayake K, Omer O, Stassen LF
Surgeon 2015 Apr;13(2):101-9. Epub 2014 Jul 30 doi: 10.1016/j.surge.2014.07.003. PMID: 25084627

Prognosis

Benefit-risk appraisal of lip-split mandibular "swing" vs. transoral approaches to posterior oral/oropharyngeal carcinomas using number needed to treat, to harm, and likelihood to be helped or harmed.
Pitak-Arnnop P, Witohendro LK, Tangmanee C, Subbalekha K, Sirintawat N, Auychai P, Meningaud JP, Neff A
Surg Oncol 2022 Sep;44:101837. Epub 2022 Aug 15 doi: 10.1016/j.suronc.2022.101837. PMID: 35985085
Factors Associated with Treatment Outcomes and Pathological Features in Patients with Osteoradionecrosis: A Retrospective Study.
Tadokoro Y, Hasegawa T, Takeda D, Murakami A, Yatagai N, Iwata E, Saito I, Kusumoto J, Akashi M
Int J Environ Res Public Health 2022 May 27;19(11) doi: 10.3390/ijerph19116565. PMID: 35682149Free PMC Article
Utilization of Anterolateral Thigh Flap and Transverse Cervical Recipient Vessels for Head and Neck Cancer Patients With Former Neck Dissection and Irradiation: A Case Series Study.
Lin KW, Huang TC, Cheng HT
Ann Plast Surg 2019 Apr;82(4):415-419. doi: 10.1097/SAP.0000000000001647. PMID: 30516556
Scapular Tip Free Flap in Composite Head and Neck Reconstruction.
Tracy JC, Brandon B, Patel SN
Otolaryngol Head Neck Surg 2019 Jan;160(1):57-62. Epub 2018 Aug 7 doi: 10.1177/0194599818791783. PMID: 30084318
A review of the Marx protocols: prevention and management of osteoradionecrosis by combining surgery and hyperbaric oxygen therapy.
Cronje FJ
SADJ 1998 Oct;53(10):469-71. PMID: 10023268

Clinical prediction guides

Benefit-risk appraisal of lip-split mandibular "swing" vs. transoral approaches to posterior oral/oropharyngeal carcinomas using number needed to treat, to harm, and likelihood to be helped or harmed.
Pitak-Arnnop P, Witohendro LK, Tangmanee C, Subbalekha K, Sirintawat N, Auychai P, Meningaud JP, Neff A
Surg Oncol 2022 Sep;44:101837. Epub 2022 Aug 15 doi: 10.1016/j.suronc.2022.101837. PMID: 35985085
2-Octyl cyanoacrylate to prevent salivary fistula formation following oral cavity microvascular reconstruction: A prospective trial.
Roof SA, Perez ER, Villavisanis DF, Khan MN, Ferrandino RM, Chouake RJ, Pacheco CW, Yao M, Teng MS, Genden EM, Miles BA
Am J Otolaryngol 2020 Sep-Oct;41(5):102552. Epub 2020 May 28 doi: 10.1016/j.amjoto.2020.102552. PMID: 32505990
Versatility and Reliability of Islanded Pedicled Nasolabial Flap in Head and Neck Cancer Reconstruction.
Chakrabarti S, Gupta DK, Gupta M, Daga D, Mishra A, Sharma SS, Chugh R, Singh SK
Laryngoscope 2020 Aug;130(8):1967-1972. Epub 2020 Apr 8 doi: 10.1002/lary.28662. PMID: 32267549
Computer-Assisted Designed and Manufactured Procedures Facilitate the Lingual Application of Mandible Reconstruction Plates.
Probst FA, Metzger M, Ehrenfeld M, Cornelius CP
J Oral Maxillofac Surg 2016 Sep;74(9):1879-95. Epub 2016 Mar 24 doi: 10.1016/j.joms.2016.03.015. PMID: 27087284
A review of the Marx protocols: prevention and management of osteoradionecrosis by combining surgery and hyperbaric oxygen therapy.
Cronje FJ
SADJ 1998 Oct;53(10):469-71. PMID: 10023268

Recent systematic reviews

Early feeding after free flap reconstruction of the oral cavity: A systematic review and meta-analysis.
Barlow J, Sragi Z, Rodriguez N, Alsen M, Kappauf C, Ferrandino R, Chennareddy S, Kotz T, Kirke DN, Teng MS, Genden EM, Khan MN, Roof SA
Head Neck 2024 May;46(5):1224-1233. Epub 2024 Feb 27 doi: 10.1002/hed.27684. PMID: 38414175
Orocutaneous Fistula After Oral Cavity Resection and Reconstruction: Systematic Review and Meta-Analysis.
Tassone P, Galloway T, Dooley L, Zitsch R 3rd
Ann Otol Rhinol Laryngol 2022 Aug;131(8):880-891. Epub 2021 Sep 23 doi: 10.1177/00034894211047463. PMID: 34553635
Management of postreconstructive head and neck salivary fistulae: A review of current practices.
Khoo MJW, Ooi ASH
J Plast Reconstr Aesthet Surg 2021 Sep;74(9):2120-2132. Epub 2021 Jan 10 doi: 10.1016/j.bjps.2020.12.096. PMID: 33551359

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