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Childhood Nodular Sclerosis Classic Hodgkin Lymphoma

MedGen UID:
76042
•Concept ID:
C0279921
•
Neoplastic Process
Synonyms: Childhood Hodgkin's Nodular Sclerosis; Childhood Nodular Sclerosis Classical Hodgkin Lymphoma; Childhood Nodular Sclerosis Hodgkin Lymphoma; Childhood Nodular Sclerosis Hodgkin's Disease; Childhood Nodular Sclerosis Hodgkin's Lymphoma; Childhood NSHD; Pediatric Hodgkin's Nodular Sclerosis; Pediatric Nodular Sclerosis Hodgkin's Disease; Pediatric Nodular Sclerosis Hodgkin's Lymphoma; Pediatric NSHD

Definition

Nodular sclerosis classic Hodgkin lymphoma occurring in childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Nodular Sclerosis Classic Hodgkin Lymphoma

Professional guidelines

PubMed

Brentuximab vedotin in the treatment of paediatric patients with relapsed or refractory Hodgkin's lymphoma: Results of a real-life study.
Massano D, Carraro E, Mussolin L, Buffardi S, Barat V, Zama D, Muggeo P, Vendemini F, Sau A, Moleti ML, Verzegnassi F, D'Amico S, Casini T, Garaventa A, Schiavello E, Cellini M, Vinti L, Farruggia P, Perruccio K, Cesaro S, De Santis R, Marinoni M, D'Alba I, Mura RM, Burnelli R, Mascarin M, Pillon M
Pediatr Blood Cancer 2022 Oct;69(10):e29801. Epub 2022 Jun 2 doi: 10.1002/pbc.29801. PMID: 35656841
Assessment of tumor Epstein-Barr Virus status and its impact on outcomes in intermediate and high-risk childhood classic Hodgkin Lymphoma treated at a tertiary cancer center in India.
Cheriyalinkal Parambil B, Narula G, Dhamne C, Roy Moulik N, Shet T, Shridhar E, Gujral S, Shah S, Laskar S, Khanna N, Banavali S
Leuk Lymphoma 2020 Dec;61(13):3217-3225. Epub 2020 Jul 30 doi: 10.1080/10428194.2020.1800005. PMID: 32729791

Recent clinical studies

Etiology

Brentuximab vedotin in the treatment of paediatric patients with relapsed or refractory Hodgkin's lymphoma: Results of a real-life study.
Massano D, Carraro E, Mussolin L, Buffardi S, Barat V, Zama D, Muggeo P, Vendemini F, Sau A, Moleti ML, Verzegnassi F, D'Amico S, Casini T, Garaventa A, Schiavello E, Cellini M, Vinti L, Farruggia P, Perruccio K, Cesaro S, De Santis R, Marinoni M, D'Alba I, Mura RM, Burnelli R, Mascarin M, Pillon M
Pediatr Blood Cancer 2022 Oct;69(10):e29801. Epub 2022 Jun 2 doi: 10.1002/pbc.29801. PMID: 35656841
Assessment of tumor Epstein-Barr Virus status and its impact on outcomes in intermediate and high-risk childhood classic Hodgkin Lymphoma treated at a tertiary cancer center in India.
Cheriyalinkal Parambil B, Narula G, Dhamne C, Roy Moulik N, Shet T, Shridhar E, Gujral S, Shah S, Laskar S, Khanna N, Banavali S
Leuk Lymphoma 2020 Dec;61(13):3217-3225. Epub 2020 Jul 30 doi: 10.1080/10428194.2020.1800005. PMID: 32729791
Disease patterns in pediatric classical Hodgkin lymphoma: a report from a developing area in Brazil.
Barros MH, Hassan R, Niedobitek G
Hematol Oncol 2011 Dec;29(4):190-5. Epub 2011 Mar 4 doi: 10.1002/hon.984. PMID: 21374695
Hodgkins lymphoma in North Jordan. Does it have a different pattern?
Almasri NM
Saudi Med J 2004 Dec;25(12):1917-21. PMID: 15711667
Epstein-Barr virus (EBV) and Hodgkin's disease in a multi-ethnic population in Malaysia.
Peh SC, Looi LM, Pallesen G
Histopathology 1997 Mar;30(3):227-33. doi: 10.1046/j.1365-2559.1997.d01-594.x. PMID: 9088951

Diagnosis

Epstein-Barr Virus in Childhood and Adolescent Classic Hodgkin Lymphoma in a French Cohort of 301 Patients.
Pereira V, Boudjemaa S, Besson C, Leblanc T, Rigaud C, Leruste A, Garnier N, Lambilliotte A, Simonin M, Curtillet C, Bonneau-Lagacherie J, Coulomb A, Landman-Parker J
J Pediatr Hematol Oncol 2022 Nov 1;44(8):e1033-e1038. Epub 2022 Jan 28 doi: 10.1097/MPH.0000000000002403. PMID: 35091521
Clinicopathologic features and therapy outcome in childhood Hodgkin's lymphoma: a report from tertiary care center in Saudi Arabia.
Alkhayat N, Alshahrani M, Elyamany G, Sedick Q, Ibrahim W, Hamzi H, Binhassan A, Othman M, Alshieban S, Aljabry MS, Asiri S, Alzouman M, Alsuhaibani O, Alabbas F, Alsharif O, Elborai Y
J Egypt Natl Canc Inst 2021 Aug 16;33(1):21. doi: 10.1186/s43046-021-00078-0. PMID: 34396456
Disease patterns in pediatric classical Hodgkin lymphoma: a report from a developing area in Brazil.
Barros MH, Hassan R, Niedobitek G
Hematol Oncol 2011 Dec;29(4):190-5. Epub 2011 Mar 4 doi: 10.1002/hon.984. PMID: 21374695
Hodgkin's lymphoma: immunohistochemical features and its association with EBV LMP-1. Experience from a South Indian hospital.
Karnik S, Srinivasan B, Nair S
Pathology 2003 Jun;35(3):207-11. doi: 10.1080/0031302031000123164. PMID: 14506963
Hodgkin's disease in childhood.
Norris DG, Burgert EO Jr, Cooper HA, Harrison EG Jr
Cancer 1975 Dec;36(6):2109-20. doi: 10.1002/cncr.2820360927. PMID: 1203866

Therapy

Brentuximab vedotin in the treatment of paediatric patients with relapsed or refractory Hodgkin's lymphoma: Results of a real-life study.
Massano D, Carraro E, Mussolin L, Buffardi S, Barat V, Zama D, Muggeo P, Vendemini F, Sau A, Moleti ML, Verzegnassi F, D'Amico S, Casini T, Garaventa A, Schiavello E, Cellini M, Vinti L, Farruggia P, Perruccio K, Cesaro S, De Santis R, Marinoni M, D'Alba I, Mura RM, Burnelli R, Mascarin M, Pillon M
Pediatr Blood Cancer 2022 Oct;69(10):e29801. Epub 2022 Jun 2 doi: 10.1002/pbc.29801. PMID: 35656841
Clinicopathologic features and therapy outcome in childhood Hodgkin's lymphoma: a report from tertiary care center in Saudi Arabia.
Alkhayat N, Alshahrani M, Elyamany G, Sedick Q, Ibrahim W, Hamzi H, Binhassan A, Othman M, Alshieban S, Aljabry MS, Asiri S, Alzouman M, Alsuhaibani O, Alabbas F, Alsharif O, Elborai Y
J Egypt Natl Canc Inst 2021 Aug 16;33(1):21. doi: 10.1186/s43046-021-00078-0. PMID: 34396456

Prognosis

Assessment of tumor Epstein-Barr Virus status and its impact on outcomes in intermediate and high-risk childhood classic Hodgkin Lymphoma treated at a tertiary cancer center in India.
Cheriyalinkal Parambil B, Narula G, Dhamne C, Roy Moulik N, Shet T, Shridhar E, Gujral S, Shah S, Laskar S, Khanna N, Banavali S
Leuk Lymphoma 2020 Dec;61(13):3217-3225. Epub 2020 Jul 30 doi: 10.1080/10428194.2020.1800005. PMID: 32729791
Hodgkin's disease in childhood.
Norris DG, Burgert EO Jr, Cooper HA, Harrison EG Jr
Cancer 1975 Dec;36(6):2109-20. doi: 10.1002/cncr.2820360927. PMID: 1203866

Clinical prediction guides

Brentuximab vedotin in the treatment of paediatric patients with relapsed or refractory Hodgkin's lymphoma: Results of a real-life study.
Massano D, Carraro E, Mussolin L, Buffardi S, Barat V, Zama D, Muggeo P, Vendemini F, Sau A, Moleti ML, Verzegnassi F, D'Amico S, Casini T, Garaventa A, Schiavello E, Cellini M, Vinti L, Farruggia P, Perruccio K, Cesaro S, De Santis R, Marinoni M, D'Alba I, Mura RM, Burnelli R, Mascarin M, Pillon M
Pediatr Blood Cancer 2022 Oct;69(10):e29801. Epub 2022 Jun 2 doi: 10.1002/pbc.29801. PMID: 35656841
Epstein-Barr Virus in Childhood and Adolescent Classic Hodgkin Lymphoma in a French Cohort of 301 Patients.
Pereira V, Boudjemaa S, Besson C, Leblanc T, Rigaud C, Leruste A, Garnier N, Lambilliotte A, Simonin M, Curtillet C, Bonneau-Lagacherie J, Coulomb A, Landman-Parker J
J Pediatr Hematol Oncol 2022 Nov 1;44(8):e1033-e1038. Epub 2022 Jan 28 doi: 10.1097/MPH.0000000000002403. PMID: 35091521
Disease patterns in pediatric classical Hodgkin lymphoma: a report from a developing area in Brazil.
Barros MH, Hassan R, Niedobitek G
Hematol Oncol 2011 Dec;29(4):190-5. Epub 2011 Mar 4 doi: 10.1002/hon.984. PMID: 21374695

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