U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Coronary Culprit Lesion

MedGen UID:
760491
•Concept ID:
C2068043
•
Finding

Definition

The lesion considered to be responsible for the acute coronary syndrome. (ACC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCoronary Culprit Lesion

Professional guidelines

PubMed

Pre-operative risk assessment and risk reduction before surgery.
Poldermans D, Hoeks SE, Feringa HH
J Am Coll Cardiol 2008 May 20;51(20):1913-24. doi: 10.1016/j.jacc.2008.03.005. PMID: 18482658
Pathophysiology and clinical management of right heart ischemia.
Goldstein JA
Curr Opin Cardiol 1999 Jul;14(4):329-39. doi: 10.1097/00001573-199907000-00009. PMID: 10448614
Right heart ischemia: pathophysiology, natural history, and clinical management.
Goldstein JA
Prog Cardiovasc Dis 1998 Jan-Feb;40(4):325-41. doi: 10.1016/s0033-0620(98)80051-0. PMID: 9449958

Recent clinical studies

Etiology

Comparison of Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Relation to Outcomes in Patients Diagnosed with Acute Coronary Syndrome During Winter -vs- Other Seasons.
Shibuya J, Kobayashi N, Asai K, Tsurumi M, Shibata Y, Uchiyama S, Okazaki H, Goda H, Tani K, Shirakabe A, Takano M, Shimizu W
Am J Cardiol 2019 Jul 1;124(1):31-38. Epub 2019 Apr 8 doi: 10.1016/j.amjcard.2019.03.045. PMID: 31027656
Relation of coronary culprit lesion morphology determined by optical coherence tomography and cardiac outcomes to preinfarction angina in patients with acute myocardial infarction.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Asai K, Seino Y, Shimizu W
Int J Cardiol 2018 Oct 15;269:356-361. Epub 2018 Jul 18 doi: 10.1016/j.ijcard.2018.07.074. PMID: 30060967
Relation of Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Cardiac Outcomes to Serum Uric Acid Levels in Patients With Acute Coronary Syndrome.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Seino Y, Shimizu W
Am J Cardiol 2018 Jul 1;122(1):17-25. Epub 2018 Mar 28 doi: 10.1016/j.amjcard.2018.03.022. PMID: 29678337
Prognostic value of culprit site neutrophils in acute coronary syndrome.
Distelmaier K, Winter MP, Dragschitz F, Redwan B, Mangold A, Gleiss A, Perkmann T, Maurer G, Adlbrecht C, Lang IM
Eur J Clin Invest 2014;44(3):257-65. Epub 2014 Jan 20 doi: 10.1111/eci.12228. PMID: 24720533
Association between angiographic culprit lesion and out-of-hospital cardiac arrest in ST-elevation myocardial infarction patients.
Velders MA, van Boven N, Boden H, van der Hoeven BL, Heestermans AA, Jukema JW, de Jonge E, Kuiper MA, van Boven AJ, Hofma SH, Schalij MJ, Umans VA
Resuscitation 2013 Nov;84(11):1530-5. Epub 2013 Jul 30 doi: 10.1016/j.resuscitation.2013.07.016. PMID: 23907098

Diagnosis

Identification of Coronary Culprit Lesion in ST Elevation Myocardial Infarction by Using Deep Learning.
Tseng LM, Chuang CY, Chua SK, Tseng VS
IEEE J Transl Eng Health Med 2023;11:70-79. Epub 2022 Dec 8 doi: 10.1109/JTEHM.2022.3227204. PMID: 36654772Free PMC Article
Comparison of Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Relation to Outcomes in Patients Diagnosed with Acute Coronary Syndrome During Winter -vs- Other Seasons.
Shibuya J, Kobayashi N, Asai K, Tsurumi M, Shibata Y, Uchiyama S, Okazaki H, Goda H, Tani K, Shirakabe A, Takano M, Shimizu W
Am J Cardiol 2019 Jul 1;124(1):31-38. Epub 2019 Apr 8 doi: 10.1016/j.amjcard.2019.03.045. PMID: 31027656
Association of Isoprostanes-Related Oxidative Stress with Vulnerability of Culprit Lesions in Diabetic Patients with Acute Coronary Syndrome.
Su G, Zhang T, Yang HX, Dai WL, Wang T, Tian L, Mi SH
Int Heart J 2019 Mar 20;60(2):271-279. Epub 2019 Feb 8 doi: 10.1536/ihj.18-233. PMID: 30745536
Impact of Accumulated Serum Uric Acid on Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Cardiac Outcomes in Patients with Acute Coronary Syndrome.
Kobayashi N, Asai K, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Goda H, Uchiyama S, Tani K, Takano M, Shimizu W
Cardiology 2018;141(4):190-198. Epub 2019 Feb 13 doi: 10.1159/000496053. PMID: 30759435
Relation of Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Cardiac Outcomes to Serum Uric Acid Levels in Patients With Acute Coronary Syndrome.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Seino Y, Shimizu W
Am J Cardiol 2018 Jul 1;122(1):17-25. Epub 2018 Mar 28 doi: 10.1016/j.amjcard.2018.03.022. PMID: 29678337

Therapy

Association between Contrast Media Volume and 1-Year Clinical Outcomes in Patients Undergoing Coronary Angiography.
Feng YQ, He XY, Song FE, Chen JY
Chin Med J (Engl) 2018 Oct 20;131(20):2424-2432. doi: 10.4103/0366-6999.243563. PMID: 30334527Free PMC Article
Impact of coronary culprit lesion calcium in patients undergoing paclitaxel-eluting stent implantation (a TAXUS-IV sub study).
Moussa I, Ellis SG, Jones M, Kereiakes DJ, McMartin D, Rutherford B, Mehran R, Collins M, Leon MB, Popma JJ, Russell ME, Stone GW
Am J Cardiol 2005 Nov 1;96(9):1242-7. Epub 2005 Sep 15 doi: 10.1016/j.amjcard.2005.06.064. PMID: 16253590
Effects of selective alpha1- and alpha2-adrenergic blockade on coronary flow reserve after coronary stenting.
Gregorini L, Marco J, Farah B, Bernies M, Palombo C, Kozàkovà M, Bossi IM, Cassagneau B, Fajadet J, Di Mario C, Albiero R, Cugno M, Grossi A, Heusch G
Circulation 2002 Dec 3;106(23):2901-7. doi: 10.1161/01.cir.0000040998.88272.a7. PMID: 12460869

Prognosis

Identification of Coronary Culprit Lesion in ST Elevation Myocardial Infarction by Using Deep Learning.
Tseng LM, Chuang CY, Chua SK, Tseng VS
IEEE J Transl Eng Health Med 2023;11:70-79. Epub 2022 Dec 8 doi: 10.1109/JTEHM.2022.3227204. PMID: 36654772Free PMC Article
Factors predicting cardiac arrest in acute coronary syndrome patients under 50: A state-wide angiographic and forensic evaluation of outcomes.
Paratz ED, van Heusden A, Smith K, Brennan A, Dinh D, Ball J, Lefkovits J, Kaye DM, Nicholls SJ, Pflaumer A, La Gerche A, Stub D; VCOR and EndUCD Investigators
Resuscitation 2022 Oct;179:124-130. Epub 2022 Aug 27 doi: 10.1016/j.resuscitation.2022.08.016. PMID: 36031075
Relation of coronary culprit lesion morphology determined by optical coherence tomography and cardiac outcomes to preinfarction angina in patients with acute myocardial infarction.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Asai K, Seino Y, Shimizu W
Int J Cardiol 2018 Oct 15;269:356-361. Epub 2018 Jul 18 doi: 10.1016/j.ijcard.2018.07.074. PMID: 30060967
Relation of Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Cardiac Outcomes to Serum Uric Acid Levels in Patients With Acute Coronary Syndrome.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Seino Y, Shimizu W
Am J Cardiol 2018 Jul 1;122(1):17-25. Epub 2018 Mar 28 doi: 10.1016/j.amjcard.2018.03.022. PMID: 29678337
Association between angiographic culprit lesion and out-of-hospital cardiac arrest in ST-elevation myocardial infarction patients.
Velders MA, van Boven N, Boden H, van der Hoeven BL, Heestermans AA, Jukema JW, de Jonge E, Kuiper MA, van Boven AJ, Hofma SH, Schalij MJ, Umans VA
Resuscitation 2013 Nov;84(11):1530-5. Epub 2013 Jul 30 doi: 10.1016/j.resuscitation.2013.07.016. PMID: 23907098

Clinical prediction guides

Identification of Coronary Culprit Lesion in ST Elevation Myocardial Infarction by Using Deep Learning.
Tseng LM, Chuang CY, Chua SK, Tseng VS
IEEE J Transl Eng Health Med 2023;11:70-79. Epub 2022 Dec 8 doi: 10.1109/JTEHM.2022.3227204. PMID: 36654772Free PMC Article
Factors predicting cardiac arrest in acute coronary syndrome patients under 50: A state-wide angiographic and forensic evaluation of outcomes.
Paratz ED, van Heusden A, Smith K, Brennan A, Dinh D, Ball J, Lefkovits J, Kaye DM, Nicholls SJ, Pflaumer A, La Gerche A, Stub D; VCOR and EndUCD Investigators
Resuscitation 2022 Oct;179:124-130. Epub 2022 Aug 27 doi: 10.1016/j.resuscitation.2022.08.016. PMID: 36031075
Association between Contrast Media Volume and 1-Year Clinical Outcomes in Patients Undergoing Coronary Angiography.
Feng YQ, He XY, Song FE, Chen JY
Chin Med J (Engl) 2018 Oct 20;131(20):2424-2432. doi: 10.4103/0366-6999.243563. PMID: 30334527Free PMC Article
Relation of coronary culprit lesion morphology determined by optical coherence tomography and cardiac outcomes to preinfarction angina in patients with acute myocardial infarction.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Asai K, Seino Y, Shimizu W
Int J Cardiol 2018 Oct 15;269:356-361. Epub 2018 Jul 18 doi: 10.1016/j.ijcard.2018.07.074. PMID: 30060967
Relation of Coronary Culprit Lesion Morphology Determined by Optical Coherence Tomography and Cardiac Outcomes to Serum Uric Acid Levels in Patients With Acute Coronary Syndrome.
Kobayashi N, Hata N, Tsurumi M, Shibata Y, Okazaki H, Shirakabe A, Takano M, Seino Y, Shimizu W
Am J Cardiol 2018 Jul 1;122(1):17-25. Epub 2018 Mar 28 doi: 10.1016/j.amjcard.2018.03.022. PMID: 29678337

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...