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Hypomagnesiuria

MedGen UID:
776406
•Concept ID:
C3203528
•
Finding; Laboratory or Test Result
Synonyms: Decreased urine magnesium; Low urine magnesium levels
 
HPO: HP:0012609

Definition

An decreased concentration of magnesium the urine. [from HPO]

Professional guidelines

PubMed

Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones.
Rodriguez Cuellar CI, Wang PZT, Freundlich M, Filler G
Pediatr Nephrol 2020 Mar;35(3):383-397. Epub 2019 Jan 4 doi: 10.1007/s00467-018-4179-9. PMID: 30607567

Recent clinical studies

Etiology

Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones.
Rodriguez Cuellar CI, Wang PZT, Freundlich M, Filler G
Pediatr Nephrol 2020 Mar;35(3):383-397. Epub 2019 Jan 4 doi: 10.1007/s00467-018-4179-9. PMID: 30607567
Metabolic evaluation of patients with urinary system stone disease: a research of pediatric and adult patients.
Oğuz U, Resorlu B, Unsal A
Int Urol Nephrol 2014 Feb;46(2):329-34. Epub 2013 Aug 23 doi: 10.1007/s11255-013-0539-3. PMID: 23975676
Elevated serum levels of Vitamin D in infants with urolithiasis.
Fallahzadeh MH, Zare J, Al-Hashemi GH, Derakhshan A, Basiratnia M, Arasteh MM, Fallahzadeh MA, Fallahzadeh MK
Iran J Kidney Dis 2012 May;6(3):186-91. PMID: 22555482
Hyperoxaluria, hypocitraturia, hypomagnesiuria, and lack of intestinal colonization by Oxalobacter formigenes in a cervical spinal cord injury patient with suprapubic cystostomy, short bowel, and nephrolithiasis.
Vaidyanathan S, von Unruh GE, Watson ID, Laube N, Willets S, Soni BL
ScientificWorldJournal 2006 Apr 6;6:2403-10. doi: 10.1100/tsw.2006.373. PMID: 17619709Free PMC Article
Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients.
Nishiura JL, Campos AH, Boim MA, Heilberg IP, Schor N
Urol Res 2004 Oct;32(5):362-6. Epub 2004 Jun 19 doi: 10.1007/s00240-004-0432-8. PMID: 15221244

Diagnosis

Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones.
Rodriguez Cuellar CI, Wang PZT, Freundlich M, Filler G
Pediatr Nephrol 2020 Mar;35(3):383-397. Epub 2019 Jan 4 doi: 10.1007/s00467-018-4179-9. PMID: 30607567
Hypercalcemia in children: three cases report with unusual clinical presentations.
Garbim BB, D Ávila L, Rigatto SZP, Quadros KRDS, Belangero VMS, Oliveira RB
J Bras Nefrol 2017 Apr-Jun;39(2):213-216. doi: 10.5935/0101-2800.20170036. PMID: 29069246
Hyperoxaluria, hypocitraturia, hypomagnesiuria, and lack of intestinal colonization by Oxalobacter formigenes in a cervical spinal cord injury patient with suprapubic cystostomy, short bowel, and nephrolithiasis.
Vaidyanathan S, von Unruh GE, Watson ID, Laube N, Willets S, Soni BL
ScientificWorldJournal 2006 Apr 6;6:2403-10. doi: 10.1100/tsw.2006.373. PMID: 17619709Free PMC Article
Urinary saturation and risk factors for calcium oxalate stone disease based on spot and 24-hour urine specimens.
Ogawa Y, Yonou H, Hokama S, Oda M, Morozumi M, Sugaya K
Front Biosci 2003 Sep 1;8:a167-76. doi: 10.2741/1139. PMID: 12957883
Metabolic evaluation of patients with recurrent idiopathic calcium nephrolithiasis.
Hess B, Hasler-Strub U, Ackermann D, Jaeger P
Nephrol Dial Transplant 1997 Jul;12(7):1362-8. doi: 10.1093/ndt/12.7.1362. PMID: 9249770

Therapy

Elevated serum levels of Vitamin D in infants with urolithiasis.
Fallahzadeh MH, Zare J, Al-Hashemi GH, Derakhshan A, Basiratnia M, Arasteh MM, Fallahzadeh MA, Fallahzadeh MK
Iran J Kidney Dis 2012 May;6(3):186-91. PMID: 22555482
Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients.
Nishiura JL, Campos AH, Boim MA, Heilberg IP, Schor N
Urol Res 2004 Oct;32(5):362-6. Epub 2004 Jun 19 doi: 10.1007/s00240-004-0432-8. PMID: 15221244
Urinary saturation and risk factors for calcium oxalate stone disease based on spot and 24-hour urine specimens.
Ogawa Y, Yonou H, Hokama S, Oda M, Morozumi M, Sugaya K
Front Biosci 2003 Sep 1;8:a167-76. doi: 10.2741/1139. PMID: 12957883
Role of inhibitor deficiency in urolithiasis. II. Deficiency grade-adjusted and intermittent augmentation therapy for magnesium and citrate deficiency.
Esen T, Akinci M, Tellaloğlu S, Koçak T
Eur Urol 1991;19(3):244-8. PMID: 1855531
Mineral homeostasis and bone mass in children treated for acute lymphoblastic leukemia.
Atkinson SA, Fraher L, Gundberg CM, Andrew M, Pai M, Barr RD
J Pediatr 1989 May;114(5):793-800. doi: 10.1016/s0022-3476(89)80138-6. PMID: 2785592

Prognosis

Educational review: role of the pediatric nephrologists in the work-up and management of kidney stones.
Rodriguez Cuellar CI, Wang PZT, Freundlich M, Filler G
Pediatr Nephrol 2020 Mar;35(3):383-397. Epub 2019 Jan 4 doi: 10.1007/s00467-018-4179-9. PMID: 30607567
High incidence of urinary stones in Uyghur children may be related to local environmental factors.
Wumaner A, Keremu A, Wumaier D, Wang Q
J Pediatr Urol 2014 Apr;10(2):289-93. Epub 2013 Sep 25 doi: 10.1016/j.jpurol.2013.09.002. PMID: 24095687
Urinary saturation and risk factors for calcium oxalate stone disease based on spot and 24-hour urine specimens.
Ogawa Y, Yonou H, Hokama S, Oda M, Morozumi M, Sugaya K
Front Biosci 2003 Sep 1;8:a167-76. doi: 10.2741/1139. PMID: 12957883
Risk factors in urinary calcium oxalate stone formation and their relation to urinary calcium oxalate supersaturation.
Ogawa Y, Hatano T
Int J Urol 1996 Sep;3(5):356-60. doi: 10.1111/j.1442-2042.1996.tb00553.x. PMID: 8886911
Role of inhibitor deficiency in urolithiasis. II. Deficiency grade-adjusted and intermittent augmentation therapy for magnesium and citrate deficiency.
Esen T, Akinci M, Tellaloğlu S, Koçak T
Eur Urol 1991;19(3):244-8. PMID: 1855531

Clinical prediction guides

High incidence of urinary stones in Uyghur children may be related to local environmental factors.
Wumaner A, Keremu A, Wumaier D, Wang Q
J Pediatr Urol 2014 Apr;10(2):289-93. Epub 2013 Sep 25 doi: 10.1016/j.jpurol.2013.09.002. PMID: 24095687
Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients.
Nishiura JL, Campos AH, Boim MA, Heilberg IP, Schor N
Urol Res 2004 Oct;32(5):362-6. Epub 2004 Jun 19 doi: 10.1007/s00240-004-0432-8. PMID: 15221244
Urinary saturation and risk factors for calcium oxalate stone disease based on spot and 24-hour urine specimens.
Ogawa Y, Yonou H, Hokama S, Oda M, Morozumi M, Sugaya K
Front Biosci 2003 Sep 1;8:a167-76. doi: 10.2741/1139. PMID: 12957883
Risk factors in urinary calcium oxalate stone formation and their relation to urinary calcium oxalate supersaturation.
Ogawa Y, Hatano T
Int J Urol 1996 Sep;3(5):356-60. doi: 10.1111/j.1442-2042.1996.tb00553.x. PMID: 8886911
Mineral homeostasis and bone mass in children treated for acute lymphoblastic leukemia.
Atkinson SA, Fraher L, Gundberg CM, Andrew M, Pai M, Barr RD
J Pediatr 1989 May;114(5):793-800. doi: 10.1016/s0022-3476(89)80138-6. PMID: 2785592

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