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Blanching

MedGen UID:
810718
•Concept ID:
C0948786
•
Sign or Symptom

Definition

Transient pallor of the skin caused by reduced blood flow to the affected region. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBlanching

Professional guidelines

PubMed

Do regional geography and race influence management of chronic spontaneous urticaria?
Mosnaim GS, Greenhawt M, Imas P, Au L, Mehlis S, Oppenheimer J, Lang D, Bernstein J, Shaker M
J Allergy Clin Immunol 2022 Dec;150(6):1260-1264.e7. doi: 10.1016/j.jaci.2022.10.017. PMID: 36481046
Characteristics and management of adolescents attending the ED with fever: a prospective multicentre study.
Borensztajn D, Hagedoorn NN, Carrol E, von Both U, Dewez JE, Emonts M, van der Flier M, de Groot R, Herberg J, Kohlmaier B, Levin M, Lim E, Maconochie I, Martinon Torres F, Nijman R, Pokorn M, Rivero-Calle I, Tsolia M, Vermont C, Zavadska D, Zenz W, Zachariasse J, Moll HA; PERFORM Consortium: Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union
BMJ Open 2022 Jan 19;12(1):e053451. doi: 10.1136/bmjopen-2021-053451. PMID: 35046001Free PMC Article
International consensus criteria for diagnosing and staging hand-arm vibration syndrome.
Poole CJM, Bovenzi M, Nilsson T, Lawson IJ, House R, Thompson A, Youakim S
Int Arch Occup Environ Health 2019 Jan;92(1):117-127. Epub 2018 Sep 27 doi: 10.1007/s00420-018-1359-7. PMID: 30264331Free PMC Article

Recent clinical studies

Etiology

A Review on Acrylamide in Food: Occurrence, Toxicity, and Mitigation Strategies.
Rifai L, Saleh FA
Int J Toxicol 2020 Mar/Apr;39(2):93-102. Epub 2020 Feb 4 doi: 10.1177/1091581820902405. PMID: 32013673
Areca nut in pathogenesis of oral submucous fibrosis: revisited.
Angadi PV, Rao SS
Oral Maxillofac Surg 2011 Mar;15(1):1-9. doi: 10.1007/s10006-010-0219-8. PMID: 20376683
Patterned laser trabeculoplasty.
Turati M, Gil-Carrasco F, Morales A, Quiroz-Mercado H, Andersen D, Marcellino G, Schuele G, Palanker D
Ophthalmic Surg Lasers Imaging 2010 Sep-Oct;41(5):538-45. doi: 10.3928/15428877-20100910-02. PMID: 20968276
Management of oral submucous fibrosis: an overview.
Angadi PV, Rao S
Oral Maxillofac Surg 2010 Sep;14(3):133-42. doi: 10.1007/s10006-010-0209-x. PMID: 20177949
Blanching and non-blanching hyperaemia.
Collier M
J Wound Care 1999 Feb;8(2):63-4. doi: 10.12968/jowc.1999.8.2.26350. PMID: 10232200

Diagnosis

Not what it seems.
McCorry EA, OHagan A, Shah S
Arch Dis Child Educ Pract Ed 2021 Aug;106(4):237-238. Epub 2019 Oct 30 doi: 10.1136/archdischild-2019-318086. PMID: 31666289
Practical strategies for the diagnosis and assessment of atopic dermatitis.
Eichenfield LF, Stein Gold LF
Semin Cutan Med Surg 2017 Mar;36(2 Suppl 2):S36-S38. doi: 10.12788/j.sder.2017.009. PMID: 28654708
Irritants and corrosives.
Tovar R, Leikin JB
Emerg Med Clin North Am 2015 Feb;33(1):117-31. Epub 2014 Nov 15 doi: 10.1016/j.emc.2014.09.009. PMID: 25455665
The skin-blanching assay.
Smit P, Neumann HA, Thio HB
J Eur Acad Dermatol Venereol 2012 Oct;26(10):1197-202. Epub 2012 Feb 4 doi: 10.1111/j.1468-3083.2012.04449.x. PMID: 22303935
Blanching and non-blanching hyperaemia.
Collier M
J Wound Care 1999 Feb;8(2):63-4. doi: 10.12968/jowc.1999.8.2.26350. PMID: 10232200

Therapy

A Review on Acrylamide in Food: Occurrence, Toxicity, and Mitigation Strategies.
Rifai L, Saleh FA
Int J Toxicol 2020 Mar/Apr;39(2):93-102. Epub 2020 Feb 4 doi: 10.1177/1091581820902405. PMID: 32013673
Irritants and corrosives.
Tovar R, Leikin JB
Emerg Med Clin North Am 2015 Feb;33(1):117-31. Epub 2014 Nov 15 doi: 10.1016/j.emc.2014.09.009. PMID: 25455665
Complications of injectable fillers, part 2: vascular complications.
DeLorenzi C
Aesthet Surg J 2014 May 1;34(4):584-600. Epub 2014 Apr 1 doi: 10.1177/1090820X14525035. PMID: 24692598
The skin-blanching assay.
Smit P, Neumann HA, Thio HB
J Eur Acad Dermatol Venereol 2012 Oct;26(10):1197-202. Epub 2012 Feb 4 doi: 10.1111/j.1468-3083.2012.04449.x. PMID: 22303935
Blanching and non-blanching hyperaemia.
Collier M
J Wound Care 1999 Feb;8(2):63-4. doi: 10.12968/jowc.1999.8.2.26350. PMID: 10232200

Prognosis

'Intraoperative predictors for clinical outcomes after microinvasive glaucoma surgery".
Rao A, Mukherjee S
PLoS One 2023;18(11):e0293212. Epub 2023 Nov 9 doi: 10.1371/journal.pone.0293212. PMID: 37943891Free PMC Article
Development of a Skin-Directed Scoring System for Stevens-Johnson Syndrome and Epidermal Necrolysis: A Delphi Consensus Exercise.
Waters M, Dobry A, Le ST, Shinkai K, Beachkofsky TM, Davis MDP, Dominguez AR, Kroshinsky D, Markova A, Micheletti RG, Mostaghimi A, Pasieka HB, Rosenbach M, Seminario-Vidal L, Trinidad J, Albrecht J, Altman EM, Arakaki R, Ardern-Jones M, Bridges AG, Cardones AR, Chadha AA, Chen JK, Chen ST, Cheng K, Daveluy S, DeNiro KL, Harp J, Keller JJ, King B, Korman AM, Lowenstein EJ, Luxenberg E, Mancuso JB, Mauskar MM, Milam P, Motaparthi K, Nelson CA, Nguyen CV, Nutan F, Ortega-Loayza AG, Patel T, Rahnama-Moghadam S, Rekhtman S, Rojek NW, Sarihan M, Shaigany S, Sharma TR, Shearer SM, Shields BE, Strowd LC, Tartar DM, Thomas C, Wanat KA, Walls AC, Zaba LC, Ziemer CM, Maverakis E, Kaffenberger BH
JAMA Dermatol 2023 Jul 1;159(7):772-777. doi: 10.1001/jamadermatol.2023.1347. PMID: 37256599Free PMC Article
The Face – A Vascular Perspective. A literature review.
von Arx T, Tamura K, Yukiya O, Lozanoff S
Swiss Dent J 2018 May 14;128(5):382-392. PMID: 29734800
The Phenylephrine Test Revisited.
Barsegian A, Botwinick A, Reddy HS
Ophthalmic Plast Reconstr Surg 2018 Mar/Apr;34(2):151-154. doi: 10.1097/IOP.0000000000000903. PMID: 28353471
Patterned laser trabeculoplasty.
Turati M, Gil-Carrasco F, Morales A, Quiroz-Mercado H, Andersen D, Marcellino G, Schuele G, Palanker D
Ophthalmic Surg Lasers Imaging 2010 Sep-Oct;41(5):538-45. doi: 10.3928/15428877-20100910-02. PMID: 20968276

Clinical prediction guides

'Intraoperative predictors for clinical outcomes after microinvasive glaucoma surgery".
Rao A, Mukherjee S
PLoS One 2023;18(11):e0293212. Epub 2023 Nov 9 doi: 10.1371/journal.pone.0293212. PMID: 37943891Free PMC Article
The erythema Q-score, an imaging biomarker for redness in skin inflammation.
Frew J, Penzi L, Suarez-Farinas M, Garcet S, Brunner PM, Czarnowicki T, Kim J, Bottomley C, Finney R, Cueto I, Fuentes-Duculan J, Ohmatsu H, Lentini T, Yanofsky V, Krueger JG, Guttman-Yassky E, Gareau D
Exp Dermatol 2021 Mar;30(3):377-383. Epub 2020 Nov 30 doi: 10.1111/exd.14224. PMID: 33113259Free PMC Article
The Phenylephrine Test Revisited.
Barsegian A, Botwinick A, Reddy HS
Ophthalmic Plast Reconstr Surg 2018 Mar/Apr;34(2):151-154. doi: 10.1097/IOP.0000000000000903. PMID: 28353471
Amlodipine-induced petechial rash.
Murthy MB, Murthy B
J Postgrad Med 2011 Oct-Dec;57(4):341-2. doi: 10.4103/0022-3859.90091. PMID: 22120868
Measurement and prediction of the rate and extent of drug delivery into and through the skin.
Russell LM, Guy RH
Expert Opin Drug Deliv 2009 Apr;6(4):355-69. doi: 10.1517/17425240902865561. PMID: 19382880

Recent systematic reviews

The glucosinolates and their bioactive derivatives in Brassica: a review on classification, biosynthesis and content in plant tissues, fate during and after processing, effect on the human organism and interaction with the gut microbiota.
Sikorska-Zimny K, Beneduce L
Crit Rev Food Sci Nutr 2021;61(15):2544-2571. Epub 2020 Jun 25 doi: 10.1080/10408398.2020.1780193. PMID: 32584172
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty.
Zhang L, Weizer JS, Musch DC
Cochrane Database Syst Rev 2017 Feb 23;2(2):CD010746. doi: 10.1002/14651858.CD010746.pub2. PMID: 28231380Free PMC Article
Topical anaesthesia for needle-related pain in newborn infants.
Foster JP, Taylor C, Spence K
Cochrane Database Syst Rev 2017 Feb 4;2(2):CD010331. doi: 10.1002/14651858.CD010331.pub2. PMID: 28160271Free PMC Article
EMLA and amethocaine for reduction of children's pain associated with needle insertion.
Lander JA, Weltman BJ, So SS
Cochrane Database Syst Rev 2006 Jul 19;(3):CD004236. doi: 10.1002/14651858.CD004236.pub2. PMID: 16856039
Lidocaine-prilocaine cream versus tetracaine gel for procedural pain in children.
Taddio A, Gurguis MG, Koren G
Ann Pharmacother 2002 Apr;36(4):687-92. doi: 10.1345/aph.1A138. PMID: 11918521

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