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Infant gastrointestinal regurgitation

MedGen UID:
818488
Concept ID:
C3813607
Finding
Synonym: GASTROESOPHAGEAL REFLUX, PEDIATRIC
SNOMED CT: Infant gastrointestinal regurgitation (722884003); Infant regurgitation (722884003)
 
OMIM®: 109350

Definition

Effortless regurgitation of gastric contents that commonly occurs in infants, usually right after feeding or burping. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInfant gastrointestinal regurgitation

Professional guidelines

PubMed

Vandenplas Y
Nat Rev Gastroenterol Hepatol 2014 Mar;11(3):147-57. Epub 2013 Oct 15 doi: 10.1038/nrgastro.2013.199. PMID: 24126561
Lightdale JR, Gremse DA; Section on Gastroenterology, Hepatology, and Nutrition
Pediatrics 2013 May;131(5):e1684-95. Epub 2013 Apr 29 doi: 10.1542/peds.2013-0421. PMID: 23629618
Tack J, Blondeau K, Boecxstaens V, Rommel N
Aliment Pharmacol Ther 2011 Apr;33(7):782-8. Epub 2011 Feb 8 doi: 10.1111/j.1365-2036.2011.04584.x. PMID: 21303399

Recent clinical studies

Etiology

Gondim MMBB, Goulart AL, Morais MB
Sao Paulo Med J 2022 Jul-Aug;140(4):540-546. doi: 10.1590/1516-3180.2021.0622.R1.29102021. PMID: 35648986Free PMC Article
Chia LW, Nguyen TVH, Phan VN, Luu TTN, Nguyen GK, Tan SY, Rajindrajith S, Benninga MA
BMC Pediatr 2022 May 27;22(1):315. doi: 10.1186/s12887-022-03378-z. PMID: 35624448Free PMC Article
Salvatore S, Barberi S, Borrelli O, Castellazzi A, Di Mauro D, Di Mauro G, Doria M, Francavilla R, Landi M, Martelli A, Miniello VL, Simeone G, Verduci E, Verga C, Zanetti MA, Staiano A; SIPPS Working Group on FGIDs
Ital J Pediatr 2016 Jul 16;42(1):68. doi: 10.1186/s13052-016-0272-5. PMID: 27423188Free PMC Article
Marseglia L, Manti S, D'Angelo G, Gitto E, Salpietro C, Centorrino A, Scalfari G, Santoro G, Impellizzeri P, Romeo C
World J Gastroenterol 2015 Jul 28;21(28):8508-15. doi: 10.3748/wjg.v21.i28.8508. PMID: 26229394Free PMC Article
Lightdale JR, Gremse DA; Section on Gastroenterology, Hepatology, and Nutrition
Pediatrics 2013 May;131(5):e1684-95. Epub 2013 Apr 29 doi: 10.1542/peds.2013-0421. PMID: 23629618

Diagnosis

Reintam Blaser A, Bachmann KF, Deane AM
Curr Opin Clin Nutr Metab Care 2023 Sep 1;26(5):463-469. Epub 2023 Jun 19 doi: 10.1097/MCO.0000000000000955. PMID: 37389469
Salvatore S, Agosti M, Baldassarre ME, D'Auria E, Pensabene L, Nosetti L, Vandenplas Y
Nutrients 2021 Jan 21;13(2) doi: 10.3390/nu13020297. PMID: 33494153Free PMC Article
Lightdale JR, Gremse DA; Section on Gastroenterology, Hepatology, and Nutrition
Pediatrics 2013 May;131(5):e1684-95. Epub 2013 Apr 29 doi: 10.1542/peds.2013-0421. PMID: 23629618
Czinn SJ, Blanchard S
Paediatr Drugs 2013 Feb;15(1):19-27. doi: 10.1007/s40272-012-0004-2. PMID: 23322552
Hyams JS
Curr Opin Pediatr 1999 Oct;11(5):375-8. doi: 10.1097/00008480-199910000-00001. PMID: 10555586

Therapy

Dargenio VN, Cristofori F, Dargenio C, Giordano P, Indrio F, Celano G, Francavilla R
Benef Microbes 2022 Aug 3;13(3):221-242. Epub 2022 Feb 25 doi: 10.3920/BM2021.0151. PMID: 35212258
Salvatore S, Barberi S, Borrelli O, Castellazzi A, Di Mauro D, Di Mauro G, Doria M, Francavilla R, Landi M, Martelli A, Miniello VL, Simeone G, Verduci E, Verga C, Zanetti MA, Staiano A; SIPPS Working Group on FGIDs
Ital J Pediatr 2016 Jul 16;42(1):68. doi: 10.1186/s13052-016-0272-5. PMID: 27423188Free PMC Article
Marseglia L, Manti S, D'Angelo G, Gitto E, Salpietro C, Centorrino A, Scalfari G, Santoro G, Impellizzeri P, Romeo C
World J Gastroenterol 2015 Jul 28;21(28):8508-15. doi: 10.3748/wjg.v21.i28.8508. PMID: 26229394Free PMC Article
Vandenplas Y
Nat Rev Gastroenterol Hepatol 2014 Mar;11(3):147-57. Epub 2013 Oct 15 doi: 10.1038/nrgastro.2013.199. PMID: 24126561
Lightdale JR, Gremse DA; Section on Gastroenterology, Hepatology, and Nutrition
Pediatrics 2013 May;131(5):e1684-95. Epub 2013 Apr 29 doi: 10.1542/peds.2013-0421. PMID: 23629618

Prognosis

Waheed A, Malone M, Samiullah S
FP Essent 2018 Mar;466:29-35. PMID: 29528207
Salvatore S, Barberi S, Borrelli O, Castellazzi A, Di Mauro D, Di Mauro G, Doria M, Francavilla R, Landi M, Martelli A, Miniello VL, Simeone G, Verduci E, Verga C, Zanetti MA, Staiano A; SIPPS Working Group on FGIDs
Ital J Pediatr 2016 Jul 16;42(1):68. doi: 10.1186/s13052-016-0272-5. PMID: 27423188Free PMC Article
Morais MB
J Pediatr (Rio J) 2016 May-Jun;92(3 Suppl 1):S46-56. Epub 2016 Mar 25 doi: 10.1016/j.jped.2016.02.008. PMID: 27020622
Marseglia L, Manti S, D'Angelo G, Gitto E, Salpietro C, Centorrino A, Scalfari G, Santoro G, Impellizzeri P, Romeo C
World J Gastroenterol 2015 Jul 28;21(28):8508-15. doi: 10.3748/wjg.v21.i28.8508. PMID: 26229394Free PMC Article
Lightdale JR, Gremse DA; Section on Gastroenterology, Hepatology, and Nutrition
Pediatrics 2013 May;131(5):e1684-95. Epub 2013 Apr 29 doi: 10.1542/peds.2013-0421. PMID: 23629618

Clinical prediction guides

Reintam Blaser A, Bachmann KF, Deane AM
Curr Opin Clin Nutr Metab Care 2023 Sep 1;26(5):463-469. Epub 2023 Jun 19 doi: 10.1097/MCO.0000000000000955. PMID: 37389469
Chia LW, Nguyen TVH, Phan VN, Luu TTN, Nguyen GK, Tan SY, Rajindrajith S, Benninga MA
BMC Pediatr 2022 May 27;22(1):315. doi: 10.1186/s12887-022-03378-z. PMID: 35624448Free PMC Article
Bellaiche M, Ludwig T, Arciszewska M, Bongers A, Gomes C, Świat A, Dakhlia F, Piollet A, Oozeer R, Vandenplas Y
J Pediatr Gastroenterol Nutr 2021 Nov 1;73(5):579-585. doi: 10.1097/MPG.0000000000003289. PMID: 34417399Free PMC Article
Oji-Mmuo CN, Jones AN, Wu EY, Speer RR, Palmer T
Neurotoxicol Teratol 2021 Jul-Aug;86:106978. Epub 2021 Apr 7 doi: 10.1016/j.ntt.2021.106978. PMID: 33838247
Vandenplas Y, Dupont C, Eigenmann P, Host A, Kuitunen M, Ribes-Koninckx C, Shah N, Shamir R, Staiano A, Szajewska H, Von Berg A
Acta Paediatr 2015 Apr;104(4):334-9. Epub 2015 Jan 29 doi: 10.1111/apa.12902. PMID: 25557474

Recent systematic reviews

Kamphorst K, Van Daele E, Vlieger AM, Daams JG, Knol J, van Elburg RM
BMJ Paediatr Open 2021;5(1):e001028. Epub 2021 Mar 3 doi: 10.1136/bmjpo-2021-001028. PMID: 33748435Free PMC Article
Ferreira-Maia AP, Matijasevich A, Wang YP
World J Gastroenterol 2016 Jul 28;22(28):6547-58. doi: 10.3748/wjg.v22.i28.6547. PMID: 27605889Free PMC Article
Morais MB
J Pediatr (Rio J) 2016 May-Jun;92(3 Suppl 1):S46-56. Epub 2016 Mar 25 doi: 10.1016/j.jped.2016.02.008. PMID: 27020622
Mugambi MN, Musekiwa A, Lombard M, Young T, Blaauw R
Nutr J 2012 Oct 4;11:81. doi: 10.1186/1475-2891-11-81. PMID: 23035863Free PMC Article
Maclennan S, Augood C, Cash-Gibson L, Logan S, Gilbert RE
Cochrane Database Syst Rev 2010 Apr 14;2010(4):CD002300. doi: 10.1002/14651858.CD002300.pub2. PMID: 20393933Free PMC Article

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