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Main Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

MedGen UID:
819729
Concept ID:
C3826981
Neoplastic Process
Synonym: Pancreatic MD-IPMN

Definition

An intraductal papillary-mucinous neoplasm of the pancreas that arises from the main pancreatic duct. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMain Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

Professional guidelines

PubMed

Lee LS
World J Gastroenterol 2021 Sep 14;27(34):5700-5714. doi: 10.3748/wjg.v27.i34.5700. PMID: 34629795Free PMC Article
Del Chiaro M, Torphy RJ, Schulick RD
J Intern Med 2021 Nov;290(5):969-979. doi: 10.1111/joim.13359. PMID: 34237168
European Study Group on Cystic Tumours of the Pancreas
Gut 2018 May;67(5):789-804. Epub 2018 Mar 24 doi: 10.1136/gutjnl-2018-316027. PMID: 29574408Free PMC Article

Recent clinical studies

Etiology

Nista EC, Schepis T, Candelli M, Giuli L, Pignataro G, Franceschi F, Gasbarrini A, Ojetti V
Int J Mol Sci 2021 Nov 27;22(23) doi: 10.3390/ijms222312839. PMID: 34884643Free PMC Article
Lee LS
World J Gastroenterol 2021 Sep 14;27(34):5700-5714. doi: 10.3748/wjg.v27.i34.5700. PMID: 34629795Free PMC Article
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
European Study Group on Cystic Tumours of the Pancreas
Gut 2018 May;67(5):789-804. Epub 2018 Mar 24 doi: 10.1136/gutjnl-2018-316027. PMID: 29574408Free PMC Article
Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC)
Pancreatology 2018 Jan;18(1):61-67. Epub 2017 Nov 20 doi: 10.1016/j.pan.2017.11.007. PMID: 29170051

Diagnosis

Nista EC, Schepis T, Candelli M, Giuli L, Pignataro G, Franceschi F, Gasbarrini A, Ojetti V
Int J Mol Sci 2021 Nov 27;22(23) doi: 10.3390/ijms222312839. PMID: 34884643Free PMC Article
Lee LS
World J Gastroenterol 2021 Sep 14;27(34):5700-5714. doi: 10.3748/wjg.v27.i34.5700. PMID: 34629795Free PMC Article
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
European Study Group on Cystic Tumours of the Pancreas
Gut 2018 May;67(5):789-804. Epub 2018 Mar 24 doi: 10.1136/gutjnl-2018-316027. PMID: 29574408Free PMC Article
Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC)
Pancreatology 2018 Jan;18(1):61-67. Epub 2017 Nov 20 doi: 10.1016/j.pan.2017.11.007. PMID: 29170051

Therapy

de la Fuente J, Chatterjee A, Lui J, Nehra AK, Bell MG, Lennon RJ, Kassmeyer BA, Graham RP, Nagayama H, Schulte PJ, Doering KA, Delgado AM, Vege SS, Chari ST, Takahashi N, Majumder S
JAMA Netw Open 2023 Oct 2;6(10):e2337799. doi: 10.1001/jamanetworkopen.2023.37799. PMID: 37847503Free PMC Article
Blair AB, Beckman RM, Habib JR, Griffin JF, Lafaro K, Burkhart RA, Burns W, Weiss MJ, Cameron JL, Wolfgang CL, He J
HPB (Oxford) 2022 May;24(5):645-653. Epub 2021 Sep 23 doi: 10.1016/j.hpb.2021.09.013. PMID: 34610896Free PMC Article
Hipp J, Mohamed S, Pott J, Sick O, Makowiec F, Hopt UT, Fichtner-Feigl S, Wittel UA
BJS Open 2019 Aug;3(4):490-499. Epub 2019 Mar 21 doi: 10.1002/bjs5.50156. PMID: 31388641Free PMC Article
Andrén-Sandberg Å, Ansorge C, Yadav TD
Dig Surg 2016;33(4):329-34. Epub 2016 May 25 doi: 10.1159/000445018. PMID: 27215746
Goh BK
World J Gastroenterol 2015 Sep 14;21(34):9833-7. doi: 10.3748/wjg.v21.i34.9833. PMID: 26379390Free PMC Article

Prognosis

Nista EC, Schepis T, Candelli M, Giuli L, Pignataro G, Franceschi F, Gasbarrini A, Ojetti V
Int J Mol Sci 2021 Nov 27;22(23) doi: 10.3390/ijms222312839. PMID: 34884643Free PMC Article
Del Chiaro M, Torphy RJ, Schulick RD
J Intern Med 2021 Nov;290(5):969-979. doi: 10.1111/joim.13359. PMID: 34237168
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
Kanno A, Masamune A, Hanada K, Maguchi H, Shimizu Y, Ueki T, Hasebe O, Ohtsuka T, Nakamura M, Takenaka M, Kitano M, Kikuyama M, Gabata T, Yoshida K, Sasaki T, Serikawa M, Furukawa T, Yanagisawa A, Shimosegawa T; Japan Study Group on the Early Detection of Pancreatic Cancer (JEDPAC)
Pancreatology 2018 Jan;18(1):61-67. Epub 2017 Nov 20 doi: 10.1016/j.pan.2017.11.007. PMID: 29170051
Attiyeh MA, Fernández-Del Castillo C, Al Efishat M, Eaton AA, Gönen M, Batts R, Pergolini I, Rezaee N, Lillemoe KD, Ferrone CR, Mino-Kenudson M, Weiss MJ, Cameron JL, Hruban RH, D'Angelica MI, DeMatteo RP, Kingham TP, Jarnagin WR, Wolfgang CL, Allen PJ
Ann Surg 2018 Jan;267(1):157-163. doi: 10.1097/SLA.0000000000002015. PMID: 28079542Free PMC Article

Clinical prediction guides

Nista EC, Schepis T, Candelli M, Giuli L, Pignataro G, Franceschi F, Gasbarrini A, Ojetti V
Int J Mol Sci 2021 Nov 27;22(23) doi: 10.3390/ijms222312839. PMID: 34884643Free PMC Article
Hirono S, Yamaue H
Surg Today 2020 Jan;50(1):50-55. Epub 2019 Dec 5 doi: 10.1007/s00595-019-01931-5. PMID: 31807871Free PMC Article
Pollini T, Andrianello S, Caravati A, Perri G, Malleo G, Paiella S, Marchegiani G, Salvia R
Minerva Chir 2019 Oct;74(5):414-421. doi: 10.23736/S0026-4733.19.08145-8. PMID: 31795628
Attiyeh MA, Fernández-Del Castillo C, Al Efishat M, Eaton AA, Gönen M, Batts R, Pergolini I, Rezaee N, Lillemoe KD, Ferrone CR, Mino-Kenudson M, Weiss MJ, Cameron JL, Hruban RH, D'Angelica MI, DeMatteo RP, Kingham TP, Jarnagin WR, Wolfgang CL, Allen PJ
Ann Surg 2018 Jan;267(1):157-163. doi: 10.1097/SLA.0000000000002015. PMID: 28079542Free PMC Article
Fritz S, Hackert T, Büchler MW
Dig Dis 2015;33(1):99-105. Epub 2014 Dec 17 doi: 10.1159/000368448. PMID: 25531503

Recent systematic reviews

Facciorusso A, Crinò SF, Ramai D, Marchegiani G, Lester J, Singh J, Lisotti A, Fusaroli P, Cannizzaro R, Gkolfakis P, Papanikolaou IS, Triantafyllou K, Singh S
Eur J Surg Oncol 2022 Mar;48(3):632-639. Epub 2021 Oct 1 doi: 10.1016/j.ejso.2021.09.018. PMID: 34620511
Zhao W, Liu S, Cong L, Zhao Y
Ann Surg Oncol 2022 Feb;29(2):1297-1312. Epub 2021 Sep 23 doi: 10.1245/s10434-021-10662-2. PMID: 34554343
Pergolini I, Schorn S, Jäger C, Göß R, Novotny A, Friess H, Ceyhan GO, Demir IE
Surgery 2021 Feb;169(2):411-418. Epub 2020 Aug 22 doi: 10.1016/j.surg.2020.07.006. PMID: 32838986
Choi SH, Park SH, Kim KW, Lee JY, Lee SS
Clin Gastroenterol Hepatol 2017 Oct;15(10):1509-1520.e4. Epub 2017 Mar 22 doi: 10.1016/j.cgh.2017.03.020. PMID: 28342950
Crippa S, Fernández-del Castillo C
Curr Gastroenterol Rep 2008 Apr;10(2):136-43. doi: 10.1007/s11894-008-0034-7. PMID: 18462599

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