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Brugada Syndrome Pattern by ECG Finding

MedGen UID:
824003
•Concept ID:
C3831255
•
Finding
Synonym: Brugada Syndrome Pattern by EKG Finding

Definition

An electrocardiographic finding of complete or incomplete right bundle branch block accompanied by ST elevation in leads V1-V3. This may be noted at rest or can be provoked by medication challenge. (CDISC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBrugada Syndrome Pattern by ECG Finding

Professional guidelines

PubMed

Brugada syndrome: Diagnosis, risk stratification and management.
Gourraud JB, Barc J, Thollet A, Le Marec H, Probst V
Arch Cardiovasc Dis 2017 Mar;110(3):188-195. Epub 2017 Jan 27 doi: 10.1016/j.acvd.2016.09.009. PMID: 28139454
Brugada syndrome and Brugada phenocopy. The importance of a differential diagnosis.
Dendramis G
Int J Cardiol 2016 May 1;210:25-7. Epub 2016 Feb 17 doi: 10.1016/j.ijcard.2016.02.097. PMID: 26922708
Differential diagnosis of rSr' pattern in leads V1 -V2. Comprehensive review and proposed algorithm.
Baranchuk A, Enriquez A, García-Niebla J, Bayés-Genís A, Villuendas R, Bayés de Luna A
Ann Noninvasive Electrocardiol 2015 Jan;20(1):7-17. Epub 2014 Dec 26 doi: 10.1111/anec.12241. PMID: 25546557Free PMC Article

Recent clinical studies

Etiology

Brugada syndrome: update and future perspectives.
Marsman EMJ, Postema PG, Remme CA
Heart 2022 May;108(9):668-675. Epub 2021 Oct 14 doi: 10.1136/heartjnl-2020-318258. PMID: 34649929
Brugada syndrome.
Korlipara H, Korlipara G, Pentyala S
Acta Cardiol 2021 Oct;76(8):805-824. Epub 2020 Jul 20 doi: 10.1080/00015385.2020.1790823. PMID: 32684122
Brugada syndrome: Diagnosis, risk stratification and management.
Gourraud JB, Barc J, Thollet A, Le Marec H, Probst V
Arch Cardiovasc Dis 2017 Mar;110(3):188-195. Epub 2017 Jan 27 doi: 10.1016/j.acvd.2016.09.009. PMID: 28139454
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Brugada syndrome.
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P
Methodist Debakey Cardiovasc J 2014 Jan-Mar;10(1):25-8. doi: 10.14797/mdcj-10-1-25. PMID: 24932359Free PMC Article

Diagnosis

Brugada syndrome: update and future perspectives.
Marsman EMJ, Postema PG, Remme CA
Heart 2022 May;108(9):668-675. Epub 2021 Oct 14 doi: 10.1136/heartjnl-2020-318258. PMID: 34649929
Brugada syndrome.
Korlipara H, Korlipara G, Pentyala S
Acta Cardiol 2021 Oct;76(8):805-824. Epub 2020 Jul 20 doi: 10.1080/00015385.2020.1790823. PMID: 32684122
Brugada syndrome: Diagnosis, risk stratification and management.
Gourraud JB, Barc J, Thollet A, Le Marec H, Probst V
Arch Cardiovasc Dis 2017 Mar;110(3):188-195. Epub 2017 Jan 27 doi: 10.1016/j.acvd.2016.09.009. PMID: 28139454
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Brugada syndrome.
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P
Methodist Debakey Cardiovasc J 2014 Jan-Mar;10(1):25-8. doi: 10.14797/mdcj-10-1-25. PMID: 24932359Free PMC Article

Therapy

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome.
D'Imperio S, Monasky MM, Micaglio E, Negro G, Pappone C
Nutrients 2021 Jul 21;13(8) doi: 10.3390/nu13082482. PMID: 34444641Free PMC Article
Brugada syndrome: Diagnosis, risk stratification and management.
Gourraud JB, Barc J, Thollet A, Le Marec H, Probst V
Arch Cardiovasc Dis 2017 Mar;110(3):188-195. Epub 2017 Jan 27 doi: 10.1016/j.acvd.2016.09.009. PMID: 28139454
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Drug-induced Brugada syndrome.
Yap YG, Behr ER, Camm AJ
Europace 2009 Aug;11(8):989-94. Epub 2009 May 29 doi: 10.1093/europace/eup114. PMID: 19482855
The Brugada syndrome.
Naccarelli GV, Antzelevitch C, Wolbrette DL, Luck JC
Curr Opin Cardiol 2002 Jan;17(1):19-23. doi: 10.1097/00001573-200201000-00003. PMID: 11790929

Prognosis

Brugada syndrome: update and future perspectives.
Marsman EMJ, Postema PG, Remme CA
Heart 2022 May;108(9):668-675. Epub 2021 Oct 14 doi: 10.1136/heartjnl-2020-318258. PMID: 34649929
Brugada syndrome.
Korlipara H, Korlipara G, Pentyala S
Acta Cardiol 2021 Oct;76(8):805-824. Epub 2020 Jul 20 doi: 10.1080/00015385.2020.1790823. PMID: 32684122
Brugada syndrome: Diagnosis, risk stratification and management.
Gourraud JB, Barc J, Thollet A, Le Marec H, Probst V
Arch Cardiovasc Dis 2017 Mar;110(3):188-195. Epub 2017 Jan 27 doi: 10.1016/j.acvd.2016.09.009. PMID: 28139454
Brugada syndrome.
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P
Methodist Debakey Cardiovasc J 2014 Jan-Mar;10(1):25-8. doi: 10.14797/mdcj-10-1-25. PMID: 24932359Free PMC Article
Brugada syndrome.
Jellins J, Milanovic M, Taitz DJ, Wan SH, Yam PW
Hong Kong Med J 2013 Apr;19(2):159-67. PMID: 23535677

Clinical prediction guides

Brugada syndrome: update and future perspectives.
Marsman EMJ, Postema PG, Remme CA
Heart 2022 May;108(9):668-675. Epub 2021 Oct 14 doi: 10.1136/heartjnl-2020-318258. PMID: 34649929
Brugada syndrome.
Korlipara H, Korlipara G, Pentyala S
Acta Cardiol 2021 Oct;76(8):805-824. Epub 2020 Jul 20 doi: 10.1080/00015385.2020.1790823. PMID: 32684122
Brugada syndrome: Diagnosis, risk stratification and management.
Gourraud JB, Barc J, Thollet A, Le Marec H, Probst V
Arch Cardiovasc Dis 2017 Mar;110(3):188-195. Epub 2017 Jan 27 doi: 10.1016/j.acvd.2016.09.009. PMID: 28139454
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118
Brugada syndrome.
Brugada R, Campuzano O, Sarquella-Brugada G, Brugada J, Brugada P
Methodist Debakey Cardiovasc J 2014 Jan-Mar;10(1):25-8. doi: 10.14797/mdcj-10-1-25. PMID: 24932359Free PMC Article

Recent systematic reviews

Investigation of High-Risk Electrocardiographic Markers as Predictors of Major Arrhythmic Events in Brugada Syndrome: A Systematic Review and Meta-analysis.
Achmad C, Kamarullah W, Putra ICS, Firmansyah DK, Iqbal M, Karwiky G, Pramudyo M, Martha JW, Akbar MR
Curr Probl Cardiol 2023 Aug;48(8):101727. Epub 2023 Mar 28 doi: 10.1016/j.cpcardiol.2023.101727. PMID: 36997139
COVID-19-associated Brugada pattern electrocardiogram: Systematic review of case reports.
Liu K, Chen K, Uzunoglu EC, Rathore A, Deol T, Wu E, Elayi CS, Suryanarayana PG, Keim SG, Catanzaro JN
Ann Noninvasive Electrocardiol 2023 May;28(3):e13051. Epub 2023 Feb 21 doi: 10.1111/anec.13051. PMID: 36811259Free PMC Article
Standard ECG in Brugada Syndrome as a Marker of Prognosis: From Risk Stratification to Pathophysiological Insights.
Vitali F, Brieda A, Balla C, Pavasini R, Tonet E, Serenelli M, Ferrari R, Delise P, Rapezzi C, Bertini M
J Am Heart Assoc 2021 May 18;10(10):e020767. Epub 2021 May 12 doi: 10.1161/JAHA.121.020767. PMID: 33977759Free PMC Article
Prognosis, risk stratification, and management of asymptomatic individuals with Brugada syndrome: A systematic review.
Letsas KP, Asvestas D, Baranchuk A, Liu T, Georgopoulos S, Efremidis M, Korantzopoulos P, Bazoukis G, Tse G, Sideris A, Takagi M, Ehrlich JR
Pacing Clin Electrophysiol 2017 Dec;40(12):1332-1345. Epub 2017 Nov 15 doi: 10.1111/pace.13214. PMID: 28994463
Risk factors for QTc-prolongation: systematic review of the evidence.
Vandael E, Vandenberk B, Vandenberghe J, Willems R, Foulon V
Int J Clin Pharm 2017 Feb;39(1):16-25. Epub 2016 Dec 23 doi: 10.1007/s11096-016-0414-2. PMID: 28012118

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