U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Papillary serous cystadenocarcinoma

MedGen UID:
825029
•Concept ID:
C3839184
•
Neoplastic Process
Synonyms: Low grade serous carcinoma; Micropapillary serous carcinoma; Micropapillary Serous Carcinoma; Micropapillary Variant of Serous Borderline Tumor; Papillary Serous Adenocarcinoma; papillary serous adenocarcinoma; Papillary Serous Carcinoma; Papillary Serous Cystadenocarcinoma; papillary serous cystadenocarcinoma; serous surface papillary carcinoma (morphologic abnormality)
SNOMED CT: Low grade serous carcinoma (703561001); Micropapillary serous carcinoma (703561001)
 
Monarch Initiative: MONDO:0002368

Definition

An adenocarcinoma usually arising from the ovary. It is characterized by the presence of complex micropapillary structures covered by round and cuboidal cells with a high nuclear to cytoplasmic ratio. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPapillary serous cystadenocarcinoma

Professional guidelines

PubMed

Diagnosis and Management of Pancreatic Cystic Neoplasms.
Kim TS, Fernandez-del Castillo C
Hematol Oncol Clin North Am 2015 Aug;29(4):655-74. Epub 2015 Jun 6 doi: 10.1016/j.hoc.2015.04.002. PMID: 26226903
Low-grade serous carcinoma: molecular features and contemporary treatment strategies.
Angarita AM, Cholakian D, Fader AN
Expert Rev Anticancer Ther 2015;15(8):893-9. Epub 2015 Jun 3 doi: 10.1586/14737140.2015.1052411. PMID: 26040191
Clinical management of uterine papillary serous carcinoma.
Roelofsen T, van Ham MA, de Hullu JA, Massuger LF
Expert Rev Anticancer Ther 2011 Jan;11(1):71-81. doi: 10.1586/era.10.199. PMID: 21166512

Recent clinical studies

Etiology

Development and identification of a prognostic nomogram model for patients with mixed cell adenocarcinoma of the ovary.
Wu H, Jiang S, Zhong P, Li W, Zhang S
J Ovarian Res 2021 Oct 21;14(1):137. doi: 10.1186/s13048-021-00896-9. PMID: 34674727Free PMC Article
NFAT Overexpression Correlates with CA72-4 and Poor Prognosis of Ovarian Clear-Cell Carcinoma Subtype.
Xin B, Ji KQ, Liu YS, Zhao XD
Reprod Sci 2021 Mar;28(3):745-756. Epub 2020 Oct 30 doi: 10.1007/s43032-020-00368-3. PMID: 33125687
Higher expression of calcineurin predicts poor prognosis in unique subtype of ovarian cancer.
Xin B, Ji KQ, Liu YS, Zhao XD
J Ovarian Res 2019 Aug 9;12(1):75. doi: 10.1186/s13048-019-0550-0. PMID: 31399054Free PMC Article
IL-17A is elevated in sera of patients with poorly differentiated ovarian papillary serous cystadenocarcinoma.
Malekzadeh M, Dehaghani AS, Ghaderi A, Doroudchi M
Cancer Biomark 2013 Jan 1;13(6):417-25. doi: 10.3233/CBM-140392. PMID: 24595078
Familial association of specific histologic types of ovarian malignancy with other malignancies.
Lorenzo Bermejo J, Rawal R, Hemminki K
Cancer 2004 Apr 1;100(7):1507-14. doi: 10.1002/cncr.20138. PMID: 15042686

Diagnosis

Development and identification of a prognostic nomogram model for patients with mixed cell adenocarcinoma of the ovary.
Wu H, Jiang S, Zhong P, Li W, Zhang S
J Ovarian Res 2021 Oct 21;14(1):137. doi: 10.1186/s13048-021-00896-9. PMID: 34674727Free PMC Article
A rare case of synchronous ovarian tumors: clinical case report and literature review.
Roşu GA, Furău GO, Ionescu CA, Dimitriu MCT, Neacşu A, Ioan RG, Călin FD, Matei A, Bănacu M, Popescu I, Gheorghiu D, Neacşu I, Bacalbaşa N, Furău CG
Rom J Morphol Embryol 2019;60(4):1365-1370. PMID: 32239119
Primary Peritoneal Papillary Serous Cystadenocarcinoma - A Rare Malignancy.
Sahu SK, Agrawal S, Shirazi N, Kapruwan H, Dasgupta P, Ghildiyal D, Singh SN
Chirurgia (Bucur) 2015 Nov-Dec;110(6):570-2. PMID: 26713835
IL-17A is elevated in sera of patients with poorly differentiated ovarian papillary serous cystadenocarcinoma.
Malekzadeh M, Dehaghani AS, Ghaderi A, Doroudchi M
Cancer Biomark 2013 Jan 1;13(6):417-25. doi: 10.3233/CBM-140392. PMID: 24595078
Stage III papillary serous cystadenocarcinoma of the ovary in a 15-year-old female.
Moen MD, Cliby WA, Wilson TO
Gynecol Oncol 1994 May;53(2):274-6. doi: 10.1006/gyno.1994.1130. PMID: 8188094

Therapy

Primary papillary serous cystadenocarcinoma of broad ligament.
Nagar YS, Singh S, Sawlani V, Pal L, Dimri K, Lal P
Australas Radiol 2005 Apr;49(2):160-2. doi: 10.1111/j.1440-1673.2005.01365.x. PMID: 15845057
A primary retroperitoneal serous cystadenocarcinoma with clinically aggressive behavior.
Kaku M, Ohara N, Seima Y, Imanishi K, Tomura N, Kobayashi A, Yamasaki M, Hirata Y, Murao S
Arch Gynecol Obstet 2004 Dec;270(4):302-6. Epub 2003 Oct 10 doi: 10.1007/s00404-003-0550-5. PMID: 14551796
Paclitaxel and carboplatin chemotherapy administered during pregnancy for advanced epithelial ovarian cancer.
Méndez LE, Mueller A, Salom E, González-Quintero VH
Obstet Gynecol 2003 Nov;102(5 Pt 2):1200-2. PMID: 14607056
Osseous metaplasia in ovarian papillary serous cystadenocarcinoma.
Bosscher J, Barnhill D, O'Connor D, Doering D, Nash J, Park R
Gynecol Oncol 1990 Nov;39(2):228-31. doi: 10.1016/0090-8258(90)90439-r. PMID: 2121630
Survival of ovarian carcinoma with or without lymph node metastasis.
Chen SS
Gynecol Oncol 1987 Jul;27(3):368-72. doi: 10.1016/0090-8258(87)90260-5. PMID: 3623232

Prognosis

Development and identification of a prognostic nomogram model for patients with mixed cell adenocarcinoma of the ovary.
Wu H, Jiang S, Zhong P, Li W, Zhang S
J Ovarian Res 2021 Oct 21;14(1):137. doi: 10.1186/s13048-021-00896-9. PMID: 34674727Free PMC Article
NFAT Overexpression Correlates with CA72-4 and Poor Prognosis of Ovarian Clear-Cell Carcinoma Subtype.
Xin B, Ji KQ, Liu YS, Zhao XD
Reprod Sci 2021 Mar;28(3):745-756. Epub 2020 Oct 30 doi: 10.1007/s43032-020-00368-3. PMID: 33125687
Higher expression of calcineurin predicts poor prognosis in unique subtype of ovarian cancer.
Xin B, Ji KQ, Liu YS, Zhao XD
J Ovarian Res 2019 Aug 9;12(1):75. doi: 10.1186/s13048-019-0550-0. PMID: 31399054Free PMC Article
Primary Peritoneal Papillary Serous Cystadenocarcinoma - A Rare Malignancy.
Sahu SK, Agrawal S, Shirazi N, Kapruwan H, Dasgupta P, Ghildiyal D, Singh SN
Chirurgia (Bucur) 2015 Nov-Dec;110(6):570-2. PMID: 26713835
Survival of ovarian carcinoma with or without lymph node metastasis.
Chen SS
Gynecol Oncol 1987 Jul;27(3):368-72. doi: 10.1016/0090-8258(87)90260-5. PMID: 3623232

Clinical prediction guides

Development and identification of a prognostic nomogram model for patients with mixed cell adenocarcinoma of the ovary.
Wu H, Jiang S, Zhong P, Li W, Zhang S
J Ovarian Res 2021 Oct 21;14(1):137. doi: 10.1186/s13048-021-00896-9. PMID: 34674727Free PMC Article
Higher expression of calcineurin predicts poor prognosis in unique subtype of ovarian cancer.
Xin B, Ji KQ, Liu YS, Zhao XD
J Ovarian Res 2019 Aug 9;12(1):75. doi: 10.1186/s13048-019-0550-0. PMID: 31399054Free PMC Article
Psammoma body: a product of dystrophic calcification or of a biologically active process that aims at limiting the growth and spread of tumor?
Das DK
Diagn Cytopathol 2009 Jul;37(7):534-41. doi: 10.1002/dc.21081. PMID: 19373908
Familial association of specific histologic types of ovarian malignancy with other malignancies.
Lorenzo Bermejo J, Rawal R, Hemminki K
Cancer 2004 Apr 1;100(7):1507-14. doi: 10.1002/cncr.20138. PMID: 15042686
Mean nuclear volume in ovarian papillary serous cystadenocarcinoma.
Mohanty SK, Dey P, Saha SC
Anal Quant Cytol Histol 2004 Feb;26(1):28-30. PMID: 15032078

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...