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Salivary gland squamous cell carcinoma

MedGen UID:
83545
•Concept ID:
C0279697
•
Neoplastic Process
Synonyms: Epidermoid Carcinoma of Salivary Gland; epidermoid carcinoma of salivary gland; Epidermoid Carcinoma of the Salivary Gland; epidermoid carcinoma of the salivary gland; saliva-secreting gland squamous cell carcinoma; Salivary Gland Epidermoid Carcinoma; salivary gland epidermoid carcinoma; Salivary Gland SCC; salivary gland SCC; salivary gland squamous cell cancer; Salivary Gland Squamous Cell Carcinoma; salivary gland squamous cell carcinoma; SCC of Salivary Gland; SCC of salivary gland; SCC of the Salivary Gland; SCC of the salivary gland; Squamous Cell Carcinoma of Salivary Gland; squamous cell carcinoma of salivary gland; squamous cell carcinoma of salivary glands; Squamous cell carcinoma of salivary glands; Squamous Cell Carcinoma of the Salivary Gland; squamous cell carcinoma of the salivary gland
 
Monarch Initiative: MONDO:0044740
Orphanet: ORPHA500481

Definition

A squamous cell carcinoma arising from the salivary glands. The majority of patients are in their sixth through eight decades. It usually presents as a rapidly enlarging mass, which may be painful. It usually has an aggressive clinical course. [from NCI]

Professional guidelines

PubMed

Patient-derived head and neck cancer organoids allow treatment stratification and serve as a tool for biomarker validation and identification.
Millen R, De Kort WWB, Koomen M, van Son GJF, Gobits R, Penning de Vries B, Begthel H, Zandvliet M, Doornaert P, Raaijmakers CPJ, Geurts MH, Elias SG, van Es RJJ, de Bree R, Devriese LA, Willems SM, Kranenburg O, Driehuis E, Clevers H
Med 2023 May 12;4(5):290-310.e12. doi: 10.1016/j.medj.2023.04.003. PMID: 37178682
The contemporary management of cancers of the sinonasal tract in adults.
Thawani R, Kim MS, Arastu A, Feng Z, West MT, Taflin NF, Thein KZ, Li R, Geltzeiler M, Lee N, Fuller CD, Grandis JR, Floudas CS, Heinrich MC, Hanna E, Chandra RA
CA Cancer J Clin 2023 Jan;73(1):72-112. Epub 2022 Aug 2 doi: 10.3322/caac.21752. PMID: 35916666Free PMC Article
Clinical Practice Guideline: Evaluation of the Neck Mass in Adults.
Pynnonen MA, Gillespie MB, Roman B, Rosenfeld RM, Tunkel DE, Bontempo L, Brook I, Chick DA, Colandrea M, Finestone SA, Fowler JC, Griffith CC, Henson Z, Levine C, Mehta V, Salama A, Scharpf J, Shatzkes DR, Stern WB, Youngerman JS, Corrigan MD
Otolaryngol Head Neck Surg 2017 Sep;157(2_suppl):S1-S30. doi: 10.1177/0194599817722550. PMID: 28891406

Recent clinical studies

Etiology

Nomogram-Based Prediction of Overall and Disease-Specific Survival in Patients With Postoperative Major Salivary Gland Squamous Cell Carcinoma.
Li L, Zhang D, Ma F
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221117405. doi: 10.1177/15330338221117405. PMID: 35950233Free PMC Article
Mutational Patterns in Metastatic Cutaneous Squamous Cell Carcinoma.
Mueller SA, Gauthier MA, Ashford B, Gupta R, Gayevskiy V, Ch'ng S, Palme CE, Shannon K, Clark JR, Ranson M, Cowley MJ
J Invest Dermatol 2019 Jul;139(7):1449-1458.e1. Epub 2019 Jan 23 doi: 10.1016/j.jid.2019.01.008. PMID: 30684551

Diagnosis

Mutational Patterns in Metastatic Cutaneous Squamous Cell Carcinoma.
Mueller SA, Gauthier MA, Ashford B, Gupta R, Gayevskiy V, Ch'ng S, Palme CE, Shannon K, Clark JR, Ranson M, Cowley MJ
J Invest Dermatol 2019 Jul;139(7):1449-1458.e1. Epub 2019 Jan 23 doi: 10.1016/j.jid.2019.01.008. PMID: 30684551

Therapy

Mutational Patterns in Metastatic Cutaneous Squamous Cell Carcinoma.
Mueller SA, Gauthier MA, Ashford B, Gupta R, Gayevskiy V, Ch'ng S, Palme CE, Shannon K, Clark JR, Ranson M, Cowley MJ
J Invest Dermatol 2019 Jul;139(7):1449-1458.e1. Epub 2019 Jan 23 doi: 10.1016/j.jid.2019.01.008. PMID: 30684551

Prognosis

Nomogram-Based Prediction of Overall and Disease-Specific Survival in Patients With Postoperative Major Salivary Gland Squamous Cell Carcinoma.
Li L, Zhang D, Ma F
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221117405. doi: 10.1177/15330338221117405. PMID: 35950233Free PMC Article

Clinical prediction guides

Nomogram-Based Prediction of Overall and Disease-Specific Survival in Patients With Postoperative Major Salivary Gland Squamous Cell Carcinoma.
Li L, Zhang D, Ma F
Technol Cancer Res Treat 2022 Jan-Dec;21:15330338221117405. doi: 10.1177/15330338221117405. PMID: 35950233Free PMC Article

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