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Pineal gland astrocytoma

MedGen UID:
83711
•Concept ID:
C0280795
•
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of pineal body; Astrocytoma of Pineal Gland; astrocytoma of pineal gland; Astrocytoma of the Pineal Gland; astrocytoma of the pineal gland; pineal astrocytic tumor; pineal astrocytic tumour; Pineal Astrocytoma; pineal astrocytoma; pineal body astrocytoma; pineal body astrocytoma (excluding glioblastoma); Pineal Gland Astrocytoma; pineal gland astrocytoma
 
Monarch Initiative: MONDO:0003171

Definition

A astrocytoma that involves the pineal body. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPineal gland astrocytoma

Professional guidelines

PubMed

Pineal Region Glioblastomas: Clinical Characteristics, Treatment, and Survival Outcome.
Niu X, Wang C, Zhou X, Yang Y, Liu Y, Zhang Y, Mao Q
World Neurosurg 2021 Feb;146:e799-e810. Epub 2020 Nov 10 doi: 10.1016/j.wneu.2020.11.016. PMID: 33186787
Diagnosis and management challenge of a granular cell astrocytoma of the pineal region: case report.
El Asri AC, Baallal H, Zoubeir Y, Sinaa M, Albouzidi A, Gazzaz M, Akhaddar A, Boucetta M, El Mostarchid B
J Neurosurg Pediatr 2015 May;15(5):506-9. Epub 2015 Feb 20 doi: 10.3171/2014.10.PEDS13388. PMID: 25700123
Management and outcome of low-grade astrocytomas of the midline in children: a retrospective review.
Hoffman HJ, Soloniuk DS, Humphreys RP, Drake JM, Becker LE, De Lima BO, Piatt JH Jr
Neurosurgery 1993 Dec;33(6):964-71. doi: 10.1227/00006123-199312000-00002. PMID: 8134009

Recent clinical studies

Etiology

Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Results of the treatment of pineal tumors in children: the Lyon experience.
Szathmari A, Beuriat PA, Vasiljevic A, Leblond P, Faure-Conter C, Claude L, Di Rocco F, Mottolese C
Childs Nerv Syst 2023 Sep;39(9):2317-2327. Epub 2022 Oct 15 doi: 10.1007/s00381-022-05649-7. PMID: 36242638
Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Pathology of pineal parenchymal tumors.
Han SJ, Clark AJ, Ivan ME, Parsa AT, Perry A
Neurosurg Clin N Am 2011 Jul;22(3):335-40, vii. Epub 2011 Jun 16 doi: 10.1016/j.nec.2011.05.006. PMID: 21801981
Pineal tumors.
Dahiya S, Perry A
Adv Anat Pathol 2010 Nov;17(6):419-27. doi: 10.1097/PAP.0b013e3181f895a4. PMID: 20966647

Diagnosis

Imagery of pineal tumors.
Deiana G, Mottolese C, Hermier M, Louis-Tisserand G, Berthezene Y
Neurochirurgie 2015 Apr-Jun;61(2-3):113-22. Epub 2015 Feb 9 doi: 10.1016/j.neuchi.2014.10.111. PMID: 25676911
Pineal tumors.
Dahiya S, Perry A
Adv Anat Pathol 2010 Nov;17(6):419-27. doi: 10.1097/PAP.0b013e3181f895a4. PMID: 20966647
Pineal tumors.
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580
Non-neoplastic pineal cysts.
Fetell MR, Bruce JN, Burke AM, Cross DT, Torres RA, Powers JM, Stein BM
Neurology 1991 Jul;41(7):1034-40. doi: 10.1212/wnl.41.7.1034. PMID: 2067630
Pineal astrocytoma.
Benjamin JC, Furneaux CE, Scholtz CL
Surg Neurol 1985 Feb;23(2):139-42. doi: 10.1016/0090-3019(85)90331-3. PMID: 3966205

Therapy

Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Pediatric intracranial primary anaplastic ganglioglioma.
Lüdemann W, Banan R, Hartmann C, Bertalanffy H, Di Rocco C
Childs Nerv Syst 2017 Feb;33(2):227-231. Epub 2016 Dec 5 doi: 10.1007/s00381-016-3302-0. PMID: 27921213
Pineal calcification is associated with pediatric primary brain tumor.
Tuntapakul S, Kitkhuandee A, Kanpittaya J, Johns J, Johns NP
Asia Pac J Clin Oncol 2016 Dec;12(4):e405-e410. Epub 2016 Jul 27 doi: 10.1111/ajco.12519. PMID: 27461152
Radiosurgery/stereotactic external beam radiotherapy for malignant brain tumours: the Royal Marsden Hospital experience.
Brada M, Laing R
Recent Results Cancer Res 1994;135:91-104. doi: 10.1007/978-3-642-85039-4_10. PMID: 7519356
Management and outcome of low-grade astrocytomas of the midline in children: a retrospective review.
Hoffman HJ, Soloniuk DS, Humphreys RP, Drake JM, Becker LE, De Lima BO, Piatt JH Jr
Neurosurgery 1993 Dec;33(6):964-71. doi: 10.1227/00006123-199312000-00002. PMID: 8134009

Prognosis

Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Pineal Region Glioblastomas: Clinical Characteristics, Treatment, and Survival Outcome.
Niu X, Wang C, Zhou X, Yang Y, Liu Y, Zhang Y, Mao Q
World Neurosurg 2021 Feb;146:e799-e810. Epub 2020 Nov 10 doi: 10.1016/j.wneu.2020.11.016. PMID: 33186787
Pineal Region Gliomas: A Single-Center Experience with 25 Cases.
Li D, Wen R, Gao Y, Xu Y, Xiong B, Gong F, Wang W
World Neurosurg 2020 Jan;133:e6-e17. Epub 2019 Jul 5 doi: 10.1016/j.wneu.2019.06.189. PMID: 31284062
Glioblastoma of pineal region: report of four cases and literature review.
Orrego E, Casavilca S, Garcia-Corrochano P, Rojas-Meza S, Castillo M, Castaneda CA
CNS Oncol 2017 Oct;6(4):251-259. Epub 2017 Oct 9 doi: 10.2217/cns-2016-0047. PMID: 28990813Free PMC Article
Pineal tumors.
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580

Clinical prediction guides

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383
Concomitant, Single Burr Hole Endoscopic Third Ventriculostomy and Tumor Biopsy for Pineal Lesions: Feasibility, Safety, and Benefits.
Leone A, Colamaria A, Fochi NP, Di Napoli V, Blagia M, Sacco M, Winkler G, Spetzger U, Almerayed W, Carbone F
World Neurosurg 2023 May;173:5-11. Epub 2023 Feb 9 doi: 10.1016/j.wneu.2023.01.082. PMID: 36764448
Signaling the Unfolded Protein Response in primary brain cancers.
Le Reste PJ, Avril T, Quillien V, Morandi X, Chevet E
Brain Res 2016 Jul 1;1642:59-69. Epub 2016 Mar 23 doi: 10.1016/j.brainres.2016.03.015. PMID: 27016056
Pathology of pineal region tumors.
Hirato J, Nakazato Y
J Neurooncol 2001 Sep;54(3):239-49. doi: 10.1023/a:1012721723387. PMID: 11767290
Non-neoplastic pineal cysts.
Fetell MR, Bruce JN, Burke AM, Cross DT, Torres RA, Powers JM, Stein BM
Neurology 1991 Jul;41(7):1034-40. doi: 10.1212/wnl.41.7.1034. PMID: 2067630

Recent systematic reviews

Primary Gamma Knife Radiosurgery for pineal region tumors: A systematic review and pooled analysis of available literature with histological stratification.
Gagliardi F, De Domenico P, Garbin E, Snider S, Mortini P
J Pineal Res 2023 Dec;75(4):e12910. Epub 2023 Sep 13 doi: 10.1111/jpi.12910. PMID: 37705383

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