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Adult Grade III Lymphomatoid Granulomatosis

MedGen UID:
853349
•Concept ID:
C1541468
•
Neoplastic Process

Definition

Grade III lymphomatoid granulomatosis that occurs in adulthood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdult Grade III Lymphomatoid Granulomatosis

Recent clinical studies

Etiology

Angiocentric immunoproliferative lesions of the skin show lobular panniculitis and are mainly disorders of large granular lymphocytes.
Takeshita M, Akamatsu M, Ohshima K, Kimura N, Suzumiya J, Kikuchi M, Okamura T, Nakayama J, Imayama S, Uike N
Hum Pathol 1995 Dec;26(12):1321-8. doi: 10.1016/0046-8177(95)90296-1. PMID: 8522304

Diagnosis

Use of rituximab in lymphomatoid granulomatosis with isolated central nervous system involvement.
Mooneyham J, Gentille C, Barbieri A, Shah S
BMJ Case Rep 2020 Sep 7;13(9) doi: 10.1136/bcr-2020-235412. PMID: 32900727Free PMC Article
Rare case of pulmonary lymphomatoid granulomatosis in conjunction with tuberculosis: A case report.
Ha YW, Kim CH, Park Y, Sohn JW, Kim MJ, Yoon YK
Medicine (Baltimore) 2017 Oct;96(42):e8323. doi: 10.1097/MD.0000000000008323. PMID: 29049243Free PMC Article
Oral lymphomatoid granulomatosis, the first sign of a 'rare disease': a case report.
Cargini P, Civica M, Sollima L, Di Cola E, Pontecorvi E, Cutilli T
J Med Case Rep 2014 May 15;8:152. doi: 10.1186/1752-1947-8-152. PMID: 24886196Free PMC Article
Cervical extramedullary lymphomatoid granulomatosis.
Montano N, Lucantoni C, Larocca LM, Papacci F, Meglio M
J Clin Neurosci 2011 Jun;18(6):851-3. Epub 2011 Apr 13 doi: 10.1016/j.jocn.2010.08.042. PMID: 21489796
Angiocentric immunoproliferative lesions of the lymph node.
Takeshita M, Akamatsu M, Ohshima K, Suzumiya J, Kikuchi M, Kimura N, Uike N, Okamura T
Am J Clin Pathol 1996 Jul;106(1):69-77. doi: 10.1093/ajcp/106.1.69. PMID: 8701936

Therapy

Use of rituximab in lymphomatoid granulomatosis with isolated central nervous system involvement.
Mooneyham J, Gentille C, Barbieri A, Shah S
BMJ Case Rep 2020 Sep 7;13(9) doi: 10.1136/bcr-2020-235412. PMID: 32900727Free PMC Article
Oral lymphomatoid granulomatosis, the first sign of a 'rare disease': a case report.
Cargini P, Civica M, Sollima L, Di Cola E, Pontecorvi E, Cutilli T
J Med Case Rep 2014 May 15;8:152. doi: 10.1186/1752-1947-8-152. PMID: 24886196Free PMC Article

Prognosis

Cervical extramedullary lymphomatoid granulomatosis.
Montano N, Lucantoni C, Larocca LM, Papacci F, Meglio M
J Clin Neurosci 2011 Jun;18(6):851-3. Epub 2011 Apr 13 doi: 10.1016/j.jocn.2010.08.042. PMID: 21489796
Angiocentric immunoproliferative lesions of the lymph node.
Takeshita M, Akamatsu M, Ohshima K, Suzumiya J, Kikuchi M, Kimura N, Uike N, Okamura T
Am J Clin Pathol 1996 Jul;106(1):69-77. doi: 10.1093/ajcp/106.1.69. PMID: 8701936
Angiocentric immunoproliferative lesions of the skin show lobular panniculitis and are mainly disorders of large granular lymphocytes.
Takeshita M, Akamatsu M, Ohshima K, Kimura N, Suzumiya J, Kikuchi M, Okamura T, Nakayama J, Imayama S, Uike N
Hum Pathol 1995 Dec;26(12):1321-8. doi: 10.1016/0046-8177(95)90296-1. PMID: 8522304

Clinical prediction guides

Proliferation and cellular phenotype in lymphomatoid granulomatosis: implications of a higher proliferation index in B cells.
Guinee DG Jr, Perkins SL, Travis WD, Holden JA, Tripp SR, Koss MN
Am J Surg Pathol 1998 Sep;22(9):1093-100. doi: 10.1097/00000478-199809000-00008. PMID: 9737242

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