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Oral Complication

MedGen UID:
857686
•Concept ID:
C3898092
•
Pathologic Function

Definition

Any oral disorder occurring as a consequence of injury to the mouth and lips. [from NCI]

Professional guidelines

PubMed

Surgical management of bisphosphonate-related osteonecrosis of the jaw in oncologic patients: a challenging problem.
Eckardt AM, Lemound J, Lindhorst D, Rana M, Gellrich NC
Anticancer Res 2011 Jun;31(6):2313-8. PMID: 21737657
Dental management of chemoradiation patients.
Chung EM, Sung EC
J Calif Dent Assoc 2006 Sep;34(9):735-42. PMID: 17022298
Bisphosphonate-associated osteonecrosis: a long-term complication of bisphosphonate treatment.
Migliorati CA, Siegel MA, Elting LS
Lancet Oncol 2006 Jun;7(6):508-14. doi: 10.1016/S1470-2045(06)70726-4. PMID: 16750501

Recent clinical studies

Etiology

Oral Care for Hematopoietic Stem Cell Transplantation Patients: A Narrative Review.
Samim F, Ten Böhmer KL, Koppelmans RGA, Raber-Durlacher JE, Epstein JB
Oral Health Prev Dent 2019;17(5):413-423. doi: 10.3290/j.ohpd.a43271. PMID: 31612159
Medication-Related Osteonecrosis of the Jaws.
Migliorati CA, Brennan MT, Peterson DE
J Natl Cancer Inst Monogr 2019 Aug 1;2019(53) doi: 10.1093/jncimonographs/lgz009. PMID: 31425596
Periodontitis: oral complication of diabetes.
Preshaw PM, Bissett SM
Endocrinol Metab Clin North Am 2013 Dec;42(4):849-67. Epub 2013 Sep 4 doi: 10.1016/j.ecl.2013.05.012. PMID: 24286953
Paresthesias in dentistry.
Moore PA, Haas DA
Dent Clin North Am 2010 Oct;54(4):715-30. doi: 10.1016/j.cden.2010.06.016. PMID: 20831934
Dental management of chemoradiation patients.
Chung EM, Sung EC
J Calif Dent Assoc 2006 Sep;34(9):735-42. PMID: 17022298

Diagnosis

Using Electronic Dental Records to Assess Osteoradionecrosis Risk in Irradiated Head and Neck Cancer.
Saenthaveesuk P, Kiat-Amnuay S, Walji MF
JDR Clin Trans Res 2023 Jul;8(3):244-256. Epub 2022 Apr 15 doi: 10.1177/23800844221089549. PMID: 35426343
Resource utilization in cancer patients with bisphosphonate-associated osteonecrosis of the jaw.
Najm MS, Solomon DH, Woo SB, Treister NS
Oral Dis 2014 Jan;20(1):94-9. Epub 2013 Feb 19 doi: 10.1111/odi.12080. PMID: 23419136Free PMC Article
Oral manifestations of diabetes mellitus and influences of periodontological treatment on diabetes mellitus.
Straka M
Bratisl Lek Listy 2011;112(7):416-20. PMID: 21744740
Managing the care of patients with bisphosphonate-associated osteonecrosis: an American Academy of Oral Medicine position paper.
Migliorati CA, Casiglia J, Epstein J, Jacobsen PL, Siegel MA, Woo SB
J Am Dent Assoc 2005 Dec;136(12):1658-68. doi: 10.14219/jada.archive.2005.0108. PMID: 16383047
Oral care of chemotherapy patients.
Rosenberg SW
Dent Clin North Am 1990 Apr;34(2):239-50. PMID: 2140102

Therapy

Chemotherapy-Induced Oral Complications and Prophylaxis Strategies.
Śledzińska A, Śledzińska P, Bebyn M, Komisarek O
Cancer Invest 2023 May;41(5):432-455. Epub 2023 Apr 20 doi: 10.1080/07357907.2023.2188558. PMID: 36892292
Probability of oral complications of radiotherapy and chemotherapy for head and neck cancer.
Coelho LHM, Silva CLA, Pedra RC, Rosado LPL, Verner FS, Aquino SN
Gen Dent 2021 Jul-Aug;69(4):70-74. PMID: 34185672
Medication-Related Osteonecrosis of the Jaws.
Migliorati CA, Brennan MT, Peterson DE
J Natl Cancer Inst Monogr 2019 Aug 1;2019(53) doi: 10.1093/jncimonographs/lgz009. PMID: 31425596
Periodontitis: oral complication of diabetes.
Preshaw PM, Bissett SM
Endocrinol Metab Clin North Am 2013 Dec;42(4):849-67. Epub 2013 Sep 4 doi: 10.1016/j.ecl.2013.05.012. PMID: 24286953
Paresthesias in dentistry.
Moore PA, Haas DA
Dent Clin North Am 2010 Oct;54(4):715-30. doi: 10.1016/j.cden.2010.06.016. PMID: 20831934

Prognosis

Thalidomide attenuates oral epithelial cell apoptosis and pro-inflammatory cytokines secretion induced by radiotherapy via the miR-9-3p/NFATC2/NF-κB axis.
Liang L, Chen L, Liu G, Jiang L, Que L, Chen J, Wang R, Zhu H
Biochem Biophys Res Commun 2022 May 7;603:102-108. Epub 2022 Mar 7 doi: 10.1016/j.bbrc.2022.03.030. PMID: 35279460
Medication-Related Osteonecrosis of the Jaws.
Migliorati CA, Brennan MT, Peterson DE
J Natl Cancer Inst Monogr 2019 Aug 1;2019(53) doi: 10.1093/jncimonographs/lgz009. PMID: 31425596
Elucidating the role of hyposalivation and autoimmunity in oral candidiasis.
Billings M, Dye BA, Iafolla T, Grisius M, Alevizos I
Oral Dis 2017 Apr;23(3):387-394. Epub 2017 Feb 8 doi: 10.1111/odi.12626. PMID: 27998016Free PMC Article
Osteonecrosis of the jaw: an update and review of recommendations.
Novince CM, Ward BB, McCauley LK
Cells Tissues Organs 2009;189(1-4):275-83. Epub 2008 Sep 1 doi: 10.1159/000152915. PMID: 18765930
Oral complication risks after invasive and non-invasive dental procedures in HIV-positive patients.
Campo J, Cano J, del Romero J, Hernando V, Rodríguez C, Bascones A
Oral Dis 2007 Jan;13(1):110-6. doi: 10.1111/j.1601-0825.2006.01262.x. PMID: 17241440

Clinical prediction guides

Using Electronic Dental Records to Assess Osteoradionecrosis Risk in Irradiated Head and Neck Cancer.
Saenthaveesuk P, Kiat-Amnuay S, Walji MF
JDR Clin Trans Res 2023 Jul;8(3):244-256. Epub 2022 Apr 15 doi: 10.1177/23800844221089549. PMID: 35426343
Thalidomide attenuates oral epithelial cell apoptosis and pro-inflammatory cytokines secretion induced by radiotherapy via the miR-9-3p/NFATC2/NF-κB axis.
Liang L, Chen L, Liu G, Jiang L, Que L, Chen J, Wang R, Zhu H
Biochem Biophys Res Commun 2022 May 7;603:102-108. Epub 2022 Mar 7 doi: 10.1016/j.bbrc.2022.03.030. PMID: 35279460
Factors associated with oral health-related quality of life in patients with diabetes.
Azogui-Lévy S, Dray-Spira R, Attal S, Hartemann A, Anagnostou F, Azerad J
Aust Dent J 2018 Jun;63(2):163-169. Epub 2018 Jan 15 doi: 10.1111/adj.12577. PMID: 29140554
Elucidating the role of hyposalivation and autoimmunity in oral candidiasis.
Billings M, Dye BA, Iafolla T, Grisius M, Alevizos I
Oral Dis 2017 Apr;23(3):387-394. Epub 2017 Feb 8 doi: 10.1111/odi.12626. PMID: 27998016Free PMC Article
Oral complication risks after invasive and non-invasive dental procedures in HIV-positive patients.
Campo J, Cano J, del Romero J, Hernando V, Rodríguez C, Bascones A
Oral Dis 2007 Jan;13(1):110-6. doi: 10.1111/j.1601-0825.2006.01262.x. PMID: 17241440

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