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Hyperacute Allograft Rejection

MedGen UID:
858427
•Concept ID:
C3898833
•
Pathologic Function

Definition

An immediate rejection of transplanted tissue caused by the presence of preformed antibodies to donor human leukocyte antigens. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHyperacute Allograft Rejection

Professional guidelines

PubMed

Management of acute severe perioperative failure of cardiac allografts: a single-centre experience with a review of the literature.
Ibrahim M, Hendry P, Masters R, Rubens F, Lam BK, Ruel M, Davies R, Haddad H, Veinot JP, Mesana T
Can J Cardiol 2007 Apr;23(5):363-7. doi: 10.1016/s0828-282x(07)70769-9. PMID: 17440641Free PMC Article
International standardization of criteria for the histologic diagnosis of renal allograft rejection: the Banff working classification of kidney transplant pathology.
Solez K, Axelsen RA, Benediktsson H, Burdick JF, Cohen AH, Colvin RB, Croker BP, Droz D, Dunnill MS, Halloran PF
Kidney Int 1993 Aug;44(2):411-22. doi: 10.1038/ki.1993.259. PMID: 8377384
Mechanism, pathophysiology, diagnosis, and management of renal transplant rejection.
Rao KV
Med Clin North Am 1990 Jul;74(4):1039-57. doi: 10.1016/s0025-7125(16)30535-1. PMID: 2114510

Recent clinical studies

Diagnosis

Fatal peri-operative hyperacute graft rejection during heart transplantation related to infusion of red blood cell concentrate.
Kennel A, Mattei S, Vanhuyse F, Proust B, Tinard X, Kaneku HN, Terasaki P, Perrier P
J Heart Lung Transplant 2012 Nov;31(11):1230-3. Epub 2012 Jul 10 doi: 10.1016/j.healun.2012.05.017. PMID: 22784933
Conundrums with FlowPRA beads.
Gebel HM, Harris SB, Zibari G, Bray RA
Clin Transplant 2002;16 Suppl 7:24-9. doi: 10.1034/j.1399-0012.16.s7.3.x. PMID: 12372040

Prognosis

Fatal peri-operative hyperacute graft rejection during heart transplantation related to infusion of red blood cell concentrate.
Kennel A, Mattei S, Vanhuyse F, Proust B, Tinard X, Kaneku HN, Terasaki P, Perrier P
J Heart Lung Transplant 2012 Nov;31(11):1230-3. Epub 2012 Jul 10 doi: 10.1016/j.healun.2012.05.017. PMID: 22784933

Clinical prediction guides

Conundrums with FlowPRA beads.
Gebel HM, Harris SB, Zibari G, Bray RA
Clin Transplant 2002;16 Suppl 7:24-9. doi: 10.1034/j.1399-0012.16.s7.3.x. PMID: 12372040

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