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Amotivation

MedGen UID:
859645
•Concept ID:
C3900051
•
Sign or Symptom

Definition

Lack of drive to participate in social activities or goal oriented behavior. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmotivation

Professional guidelines

PubMed

Clinical utility and psychometric properties of the Apathy Evaluation Scale.
Lee B, Gleason C, Umucu E
Rehabil Psychol 2020 Aug;65(3):311-312. doi: 10.1037/rep0000356. PMID: 32804534Free PMC Article
Individual negative symptoms and domains - Relevance for assessment, pathomechanisms and treatment.
Kaiser S, Lyne J, Agartz I, Clarke M, Mørch-Johnsen L, Faerden A
Schizophr Res 2017 Aug;186:39-45. Epub 2016 Jul 21 doi: 10.1016/j.schres.2016.07.013. PMID: 27453425
Secondary negative symptoms - A review of mechanisms, assessment and treatment.
Kirschner M, Aleman A, Kaiser S
Schizophr Res 2017 Aug;186:29-38. Epub 2016 May 24 doi: 10.1016/j.schres.2016.05.003. PMID: 27230288

Recent clinical studies

Etiology

Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis.
Hindley G, Beck K, Borgan F, Ginestet CE, McCutcheon R, Kleinloog D, Ganesh S, Radhakrishnan R, D'Souza DC, Howes OD
Lancet Psychiatry 2020 Apr;7(4):344-353. Epub 2020 Mar 17 doi: 10.1016/S2215-0366(20)30074-2. PMID: 32197092Free PMC Article
Expressive deficits and amotivation as mediators of the associations between cognitive problems and functional outcomes: Results from two independent cohorts.
Liemburg EJ, Enriquez-Geppert S, Wardenaar KJ, Bruggeman R, Aleman A; PROGR-S investigators; GROUP investigators
Schizophr Res 2020 Apr;218:283-291. Epub 2020 Jan 13 doi: 10.1016/j.schres.2019.12.018. PMID: 31948899
Intrinsic motivation and amotivation in first episode and prolonged psychosis.
Luther L, Lysaker PH, Firmin RL, Breier A, Vohs JL
Schizophr Res 2015 Dec;169(1-3):418-422. Epub 2015 Sep 16 doi: 10.1016/j.schres.2015.08.040. PMID: 26386901
Antipsychotics and amotivation.
Fervaha G, Takeuchi H, Lee J, Foussias G, Fletcher PJ, Agid O, Remington G
Neuropsychopharmacology 2015 May;40(6):1539-48. Epub 2015 Jan 8 doi: 10.1038/npp.2015.3. PMID: 25567425Free PMC Article
Negative symptoms: psychopathological models.
Ananth J, Djenderdjian A, Shamasunder P, Costa J, Herrera J, Sramek J
J Psychiatry Neurosci 1991 Mar;16(1):12-8. PMID: 2049366Free PMC Article

Diagnosis

Ambition and Its Psychopathologies.
Yager J, Kay J
J Nerv Ment Dis 2023 Apr 1;211(4):257-265. doi: 10.1097/NMD.0000000000001644. PMID: 36975544
Categorizing and assessing negative symptoms.
Bucci P, Galderisi S
Curr Opin Psychiatry 2017 May;30(3):201-208. doi: 10.1097/YCO.0000000000000322. PMID: 28212174
Neural Basis of Anhedonia and Amotivation in Patients with Schizophrenia: The Role of Reward System.
Lee JS, Jung S, Park IH, Kim JJ
Curr Neuropharmacol 2015;13(6):750-9. doi: 10.2174/1570159x13666150612230333. PMID: 26630955Free PMC Article
Intrinsic motivation and amotivation in first episode and prolonged psychosis.
Luther L, Lysaker PH, Firmin RL, Breier A, Vohs JL
Schizophr Res 2015 Dec;169(1-3):418-422. Epub 2015 Sep 16 doi: 10.1016/j.schres.2015.08.040. PMID: 26386901
Ketamine-Induced Hallucinations.
Powers AR 3rd, Gancsos MG, Finn ES, Morgan PT, Corlett PR
Psychopathology 2015;48(6):376-85. Epub 2015 Sep 12 doi: 10.1159/000438675. PMID: 26361209Free PMC Article

Therapy

A meta-analysis of self-determination theory-informed intervention studies in the health domain: effects on motivation, health behavior, physical, and psychological health.
Ntoumanis N, Ng JYY, Prestwich A, Quested E, Hancox JE, Thøgersen-Ntoumani C, Deci EL, Ryan RM, Lonsdale C, Williams GC
Health Psychol Rev 2021 Jun;15(2):214-244. Epub 2020 Feb 3 doi: 10.1080/17437199.2020.1718529. PMID: 31983293
Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis.
Hindley G, Beck K, Borgan F, Ginestet CE, McCutcheon R, Kleinloog D, Ganesh S, Radhakrishnan R, D'Souza DC, Howes OD
Lancet Psychiatry 2020 Apr;7(4):344-353. Epub 2020 Mar 17 doi: 10.1016/S2215-0366(20)30074-2. PMID: 32197092Free PMC Article
Sport motivation and doping in adolescent athletes.
Mudrak J, Slepicka P, Slepickova I
PLoS One 2018;13(10):e0205222. Epub 2018 Oct 4 doi: 10.1371/journal.pone.0205222. PMID: 30286200Free PMC Article
Ketamine-Induced Hallucinations.
Powers AR 3rd, Gancsos MG, Finn ES, Morgan PT, Corlett PR
Psychopathology 2015;48(6):376-85. Epub 2015 Sep 12 doi: 10.1159/000438675. PMID: 26361209Free PMC Article
Antipsychotics and amotivation.
Fervaha G, Takeuchi H, Lee J, Foussias G, Fletcher PJ, Agid O, Remington G
Neuropsychopharmacology 2015 May;40(6):1539-48. Epub 2015 Jan 8 doi: 10.1038/npp.2015.3. PMID: 25567425Free PMC Article

Prognosis

Cognitive effort and amotivation in first-episode psychosis.
Fortgang RG, Srihari V, Cannon TD
J Abnorm Psychol 2020 May;129(4):422-431. Epub 2020 Mar 12 doi: 10.1037/abn0000509. PMID: 32162929
Sport motivation and doping in adolescent athletes.
Mudrak J, Slepicka P, Slepickova I
PLoS One 2018;13(10):e0205222. Epub 2018 Oct 4 doi: 10.1371/journal.pone.0205222. PMID: 30286200Free PMC Article
Intrinsic motivation and amotivation in first episode and prolonged psychosis.
Luther L, Lysaker PH, Firmin RL, Breier A, Vohs JL
Schizophr Res 2015 Dec;169(1-3):418-422. Epub 2015 Sep 16 doi: 10.1016/j.schres.2015.08.040. PMID: 26386901
Ketamine-Induced Hallucinations.
Powers AR 3rd, Gancsos MG, Finn ES, Morgan PT, Corlett PR
Psychopathology 2015;48(6):376-85. Epub 2015 Sep 12 doi: 10.1159/000438675. PMID: 26361209Free PMC Article
Negative symptoms: psychopathological models.
Ananth J, Djenderdjian A, Shamasunder P, Costa J, Herrera J, Sramek J
J Psychiatry Neurosci 1991 Mar;16(1):12-8. PMID: 2049366Free PMC Article

Clinical prediction guides

A meta-analysis of self-determination theory-informed intervention studies in the health domain: effects on motivation, health behavior, physical, and psychological health.
Ntoumanis N, Ng JYY, Prestwich A, Quested E, Hancox JE, Thøgersen-Ntoumani C, Deci EL, Ryan RM, Lonsdale C, Williams GC
Health Psychol Rev 2021 Jun;15(2):214-244. Epub 2020 Feb 3 doi: 10.1080/17437199.2020.1718529. PMID: 31983293
Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis.
Hindley G, Beck K, Borgan F, Ginestet CE, McCutcheon R, Kleinloog D, Ganesh S, Radhakrishnan R, D'Souza DC, Howes OD
Lancet Psychiatry 2020 Apr;7(4):344-353. Epub 2020 Mar 17 doi: 10.1016/S2215-0366(20)30074-2. PMID: 32197092Free PMC Article
Sport motivation and doping in adolescent athletes.
Mudrak J, Slepicka P, Slepickova I
PLoS One 2018;13(10):e0205222. Epub 2018 Oct 4 doi: 10.1371/journal.pone.0205222. PMID: 30286200Free PMC Article
Ketamine-Induced Hallucinations.
Powers AR 3rd, Gancsos MG, Finn ES, Morgan PT, Corlett PR
Psychopathology 2015;48(6):376-85. Epub 2015 Sep 12 doi: 10.1159/000438675. PMID: 26361209Free PMC Article
Antipsychotics and amotivation.
Fervaha G, Takeuchi H, Lee J, Foussias G, Fletcher PJ, Agid O, Remington G
Neuropsychopharmacology 2015 May;40(6):1539-48. Epub 2015 Jan 8 doi: 10.1038/npp.2015.3. PMID: 25567425Free PMC Article

Recent systematic reviews

Self-determination theory interventions versus usual care in people with diabetes: a systematic review with meta-analysis and trial sequential analysis.
Mathiesen AS, Zoffmann V, Lindschou J, Jakobsen JC, Gluud C, Due-Christensen M, Rasmussen B, Marqvorsen EHS, Lund-Jacobsen T, Skytte TB, Thomsen T, Rothmann MJ
Syst Rev 2023 Sep 6;12(1):158. doi: 10.1186/s13643-023-02308-z. PMID: 37674180Free PMC Article
Effects of out-of-school physical activity interventions based on self-determination theory in children and adolescents: A systematic review and meta-analysis.
Tapia-Serrano MÁ, López-Gajardo MA, Sánchez-Miguel PA, González-Ponce I, García-Calvo T, Pulido JJ, Leo FM
Scand J Med Sci Sports 2023 Oct;33(10):1929-1947. Epub 2023 Jun 28 doi: 10.1111/sms.14436. PMID: 37381660
The acute and non-acute effects of cannabis on reward processing: A systematic review.
Skumlien M, Langley C, Lawn W, Voon V, Curran HV, Roiser JP, Sahakian BJ
Neurosci Biobehav Rev 2021 Nov;130:512-528. Epub 2021 Sep 9 doi: 10.1016/j.neubiorev.2021.09.008. PMID: 34509513
Psychiatric symptoms caused by cannabis constituents: a systematic review and meta-analysis.
Hindley G, Beck K, Borgan F, Ginestet CE, McCutcheon R, Kleinloog D, Ganesh S, Radhakrishnan R, D'Souza DC, Howes OD
Lancet Psychiatry 2020 Apr;7(4):344-353. Epub 2020 Mar 17 doi: 10.1016/S2215-0366(20)30074-2. PMID: 32197092Free PMC Article
Self-determined motivation and physical activity in children and adolescents: a systematic review and meta-analysis.
B Owen K, Smith J, Lubans DR, Ng JY, Lonsdale C
Prev Med 2014 Oct;67:270-9. Epub 2014 Jul 26 doi: 10.1016/j.ypmed.2014.07.033. PMID: 25073077

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