U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Acute Myocardial Ischemia by ECG Assessment

MedGen UID:
859702
•Concept ID:
C3900108
•
Finding

Definition

An electrocardiographic finding assessment of new or presumed new significant ST-segment-T wave (ST-T) changes or new left bundle branch block consistent with acute myocardial ischemia. (Thygesen K, Alpert JS, Jaffe AS, et al.: the Writing Group on behalf of the Joint ESC/ACCF/AHA/WHF Task Force for the Universal Definition of Myocardial Infarction. J Am Coll Cardiol 60(16):1-18, 2012) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute Myocardial Ischemia by ECG Assessment

Professional guidelines

PubMed

Contemporary NSTEMI management: the role of the hospitalist.
Pollack CV, Amin A, Wang T, Deitelzweig S, Cohen M, Slattery D, Fanikos J, DiLascia C, Tuder R, Kaatz S
Hosp Pract (1995) 2020 Feb;48(1):1-11. Epub 2020 Feb 20 doi: 10.1080/21548331.2020.1701329. PMID: 31815570
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC).
Roffi M, Patrono C, Collet JP, Mueller C, Valgimigli M, Andreotti F, Bax JJ, Borger MA, Brotons C, Chew DP, Gencer B, Hasenfuss G, Kjeldsen K, Lancellotti P, Landmesser U, Mehilli J, Mukherjee D, Storey RF, Windecker S; ESC Scientific Document Group
Eur Heart J 2016 Jan 14;37(3):267-315. Epub 2015 Aug 29 doi: 10.1093/eurheartj/ehv320. PMID: 26320110
2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, Jaffe AS, Jneid H, Kelly RF, Kontos MC, Levine GN, Liebson PR, Mukherjee D, Peterson ED, Sabatine MS, Smalling RW, Zieman SJ
J Am Coll Cardiol 2014 Dec 23;64(24):e139-e228. Epub 2014 Sep 23 doi: 10.1016/j.jacc.2014.09.017. PMID: 25260718

Recent clinical studies

Etiology

Acute Chest Pain in Adults: Outpatient Evaluation.
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
State-of-the-art diagnosis of myocardial infarction.
Vafaie M
Diagnosis (Berl) 2016 Dec 1;3(4):137-142. doi: 10.1515/dx-2016-0024. PMID: 29536900
Advanced ECG in 2016: is there more than just a tracing?
Reichlin T, Abächerli R, Twerenbold R, Kühne M, Schaer B, Müller C, Sticherling C, Osswald S
Swiss Med Wkly 2016;146:w14303. Epub 2016 Apr 28 doi: 10.4414/smw.2016.14303. PMID: 27124801
2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, Jaffe AS, Jneid H, Kelly RF, Kontos MC, Levine GN, Liebson PR, Mukherjee D, Peterson ED, Sabatine MS, Smalling RW, Zieman SJ
J Am Coll Cardiol 2014 Dec 23;64(24):e139-e228. Epub 2014 Sep 23 doi: 10.1016/j.jacc.2014.09.017. PMID: 25260718
Multi-Ethnic Study of Atherosclerosis: objectives and design.
Bild DE, Bluemke DA, Burke GL, Detrano R, Diez Roux AV, Folsom AR, Greenland P, Jacob DR Jr, Kronmal R, Liu K, Nelson JC, O'Leary D, Saad MF, Shea S, Szklo M, Tracy RP
Am J Epidemiol 2002 Nov 1;156(9):871-81. doi: 10.1093/aje/kwf113. PMID: 12397006

Diagnosis

Acute Chest Pain in Adults: Outpatient Evaluation.
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
State-of-the-art diagnosis of myocardial infarction.
Vafaie M
Diagnosis (Berl) 2016 Dec 1;3(4):137-142. doi: 10.1515/dx-2016-0024. PMID: 29536900
Advanced ECG in 2016: is there more than just a tracing?
Reichlin T, Abächerli R, Twerenbold R, Kühne M, Schaer B, Müller C, Sticherling C, Osswald S
Swiss Med Wkly 2016;146:w14303. Epub 2016 Apr 28 doi: 10.4414/smw.2016.14303. PMID: 27124801
2014 AHA/ACC Guideline for the Management of Patients with Non-ST-Elevation Acute Coronary Syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.
Amsterdam EA, Wenger NK, Brindis RG, Casey DE Jr, Ganiats TG, Holmes DR Jr, Jaffe AS, Jneid H, Kelly RF, Kontos MC, Levine GN, Liebson PR, Mukherjee D, Peterson ED, Sabatine MS, Smalling RW, Zieman SJ
J Am Coll Cardiol 2014 Dec 23;64(24):e139-e228. Epub 2014 Sep 23 doi: 10.1016/j.jacc.2014.09.017. PMID: 25260718
Multi-Ethnic Study of Atherosclerosis: objectives and design.
Bild DE, Bluemke DA, Burke GL, Detrano R, Diez Roux AV, Folsom AR, Greenland P, Jacob DR Jr, Kronmal R, Liu K, Nelson JC, O'Leary D, Saad MF, Shea S, Szklo M, Tracy RP
Am J Epidemiol 2002 Nov 1;156(9):871-81. doi: 10.1093/aje/kwf113. PMID: 12397006

Therapy

Rule-out of non-ST-segment elevation acute coronary syndrome by a single, pre-hospital troponin measurement: a randomized trial.
Camaro C, Aarts GWA, Adang EMM, van Hout R, Brok G, Hoare A, Rodwell L, de Pooter F, de Wit W, Cramer GE, van Kimmenade RRJ, Damman P, Ouwendijk E, Rutten M, Zegers E, van Geuns RM, Gomes MER, van Royen N
Eur Heart J 2023 May 14;44(19):1705-1714. doi: 10.1093/eurheartj/ehad056. PMID: 36755110Free PMC Article
Myocardial Ischemia Induced by 5-Fluorouracil: A Prospective Electrocardiographic and Cardiac Biomarker Study.
Dyhl-Polk A, Schou M, Vistisen KK, Sillesen AS, Serup-Hansen E, Faber J, Klausen TW, Bojesen SE, Vaage-Nilsen M, Nielsen DL
Oncologist 2021 Mar;26(3):e403-e413. Epub 2020 Oct 7 doi: 10.1002/onco.13536. PMID: 32959474Free PMC Article
Contemporary NSTEMI management: the role of the hospitalist.
Pollack CV, Amin A, Wang T, Deitelzweig S, Cohen M, Slattery D, Fanikos J, DiLascia C, Tuder R, Kaatz S
Hosp Pract (1995) 2020 Feb;48(1):1-11. Epub 2020 Feb 20 doi: 10.1080/21548331.2020.1701329. PMID: 31815570
Coronary microcirculation in acute myocardial ischaemia: From non-invasive to invasive absolute flow assessment.
Adjedj J, Picard F, Durand-Viel G, Sigal-Cinqualbre A, Daou D, Diebold B, Varenne O
Arch Cardiovasc Dis 2018 Apr;111(4):306-315. Epub 2018 Apr 2 doi: 10.1016/j.acvd.2018.02.003. PMID: 29622520
Acute coronary syndrome.
Overbaugh KJ
Am J Nurs 2009 May;109(5):42-52; quiz 53. doi: 10.1097/01.NAJ.0000351508.39509.e2. PMID: 19411905

Prognosis

Coronary computed tomography angiography in patients with stable coronary artery disease.
Feldman DI, Latina J, Lovell J, Blumenthal RS, Arbab-Zadeh A
Trends Cardiovasc Med 2022 Oct;32(7):421-428. Epub 2021 Aug 25 doi: 10.1016/j.tcm.2021.08.009. PMID: 34454051
Acute Chest Pain in Adults: Outpatient Evaluation.
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
Bundle branch blocks and/or hemiblocks complicating acute myocardial ischemia or infarction.
Lévy S
J Interv Card Electrophysiol 2018 Aug;52(3):287-292. Epub 2018 Aug 22 doi: 10.1007/s10840-018-0430-3. PMID: 30136134
Coronary microcirculation in acute myocardial ischaemia: From non-invasive to invasive absolute flow assessment.
Adjedj J, Picard F, Durand-Viel G, Sigal-Cinqualbre A, Daou D, Diebold B, Varenne O
Arch Cardiovasc Dis 2018 Apr;111(4):306-315. Epub 2018 Apr 2 doi: 10.1016/j.acvd.2018.02.003. PMID: 29622520
Takotsubo cardiomyopathy: an integrated multi-imaging approach.
Bossone E, Lyon A, Citro R, Athanasiadis A, Meimoun P, Parodi G, Cimarelli S, Omerovic E, Ferrara F, Limongelli G, Cittadini A, Salerno-Uriarte JA, Perrone Filardi P, Schneider B, Sechtem U, Erbel R
Eur Heart J Cardiovasc Imaging 2014 Apr;15(4):366-77. Epub 2013 Oct 14 doi: 10.1093/ehjci/jet167. PMID: 24128655

Clinical prediction guides

Rule-out of non-ST-segment elevation acute coronary syndrome by a single, pre-hospital troponin measurement: a randomized trial.
Camaro C, Aarts GWA, Adang EMM, van Hout R, Brok G, Hoare A, Rodwell L, de Pooter F, de Wit W, Cramer GE, van Kimmenade RRJ, Damman P, Ouwendijk E, Rutten M, Zegers E, van Geuns RM, Gomes MER, van Royen N
Eur Heart J 2023 May 14;44(19):1705-1714. doi: 10.1093/eurheartj/ehad056. PMID: 36755110Free PMC Article
Acute Chest Pain in Adults: Outpatient Evaluation.
McConaghy JR, Sharma M, Patel H
Am Fam Physician 2020 Dec 15;102(12):721-727. PMID: 33320506
Bundle branch blocks and/or hemiblocks complicating acute myocardial ischemia or infarction.
Lévy S
J Interv Card Electrophysiol 2018 Aug;52(3):287-292. Epub 2018 Aug 22 doi: 10.1007/s10840-018-0430-3. PMID: 30136134
State-of-the-art diagnosis of myocardial infarction.
Vafaie M
Diagnosis (Berl) 2016 Dec 1;3(4):137-142. doi: 10.1515/dx-2016-0024. PMID: 29536900
Advanced ECG in 2016: is there more than just a tracing?
Reichlin T, Abächerli R, Twerenbold R, Kühne M, Schaer B, Müller C, Sticherling C, Osswald S
Swiss Med Wkly 2016;146:w14303. Epub 2016 Apr 28 doi: 10.4414/smw.2016.14303. PMID: 27124801

Recent systematic reviews

Oxygen in the Setting of Acute Myocardial Infarction: Is It Really a Breath of Fresh Air?
Loomba RS, Nijhawan K, Aggarwal S, Arora RR
J Cardiovasc Pharmacol Ther 2016 Mar;21(2):143-9. Epub 2015 Aug 3 doi: 10.1177/1074248415598004. PMID: 26240074
Cardioprotective role of ischemic postconditioning in acute myocardial infarction: a systematic review and meta-analysis.
Khan AR, Binabdulhak AA, Alastal Y, Khan S, Faricy-Beredo BM, Luni FK, Lee WM, Khuder S, Tinkel J
Am Heart J 2014 Oct;168(4):512-521.e4. Epub 2014 Jul 12 doi: 10.1016/j.ahj.2014.06.021. PMID: 25262261
Point-of-care tests in suspected acute myocardial infarction: a systematic review.
Bruins Slot MH, van der Heijden GJ, Stelpstra SD, Hoes AW, Rutten FH
Int J Cardiol 2013 Oct 15;168(6):5355-62. Epub 2013 Aug 15 doi: 10.1016/j.ijcard.2013.08.002. PMID: 24001699
Systematic review, meta-analysis and economic modelling of diagnostic strategies for suspected acute coronary syndrome.
Goodacre S, Thokala P, Carroll C, Stevens JW, Leaviss J, Al Khalaf M, Collinson P, Morris F, Evans P, Wang J
Health Technol Assess 2013;17(1):v-vi, 1-188. doi: 10.3310/hta17010. PMID: 23331845Free PMC Article
Systematic review and modelling of the investigation of acute and chronic chest pain presenting in primary care.
Mant J, McManus RJ, Oakes RA, Delaney BC, Barton PM, Deeks JJ, Hammersley L, Davies RC, Davies MK, Hobbs FD
Health Technol Assess 2004 Feb;8(2):iii, 1-158. doi: 10.3310/hta8020. PMID: 14754562

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...