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Sclerosis of toe phalanx

MedGen UID:: 866586
•Concept ID:: C4020932
•: Anatomical Abnormality

Synonyms:	Increased bone density in the toe bone; Sclerosis of the phalanges of the toes

HPO:	HP:0100924

Definition

An elevation in bone density in one or more phalanges of the toes. Sclerosis is normally detected on a radiograph as an area of increased opacity. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVSclerosis of toe phalanx

Abnormal skeletal morphology
- Abnormal bone structure
  - Abnormal bone ossification
    - Abnormality of bone mineral density
      - Increased bone mineral density
        Sclerosis of foot bone
        Sclerosis of toe phalanx
        Patchy sclerosis of toe phalanx
        Sclerosis of 2nd toe phalanx
        Patchy sclerosis of 2nd toe phalanx
        Sclerosis of 3rd toe phalanx
        Patchy sclerosis of 3rd toe phalanx
        Sclerosis of 4th toe phalanx
        Patchy sclerosis of 4th toe phalanx
        Sclerosis of 5th toe phalanx
        Patchy sclerosis of 5th toe phalanx
        Sclerosis of distal toe phalanx
        Patchy sclerosis of distal toe phalanx
        Sclerosis of the distal phalanx of the 2nd toe
        Patchy sclerosis of the distal phalanx of the 2nd toe
        Sclerosis of the distal phalanx of the 3rd toe
        Patchy sclerosis of the distal phalanx of the 3rd toe
        Sclerosis of the distal phalanx of the 4th toe
        Patchy sclerosis of the distal phalanx of the 4th toe
        Sclerosis of the distal phalanx of the 5th toe
        Patchy sclerosis of the distal phalanx of the 5th toe
        Sclerosis of the distal phalanx of the hallux
        Patchy sclerosis of the distal phalanx of the hallux
        Sclerosis of hallux phalanx
        Patchy sclerosis of hallux phalanx
        Sclerosis of the 1st metatarsal
        Patchy sclerosis of the 1st metatarsal
        Sclerosis of middle toe phalanx
        Patchy sclerosis of middle toe phalanx
        Sclerosis of the middle phalanx of the 2nd toe
        Patchy sclerosis of the middle phalanx of the 2nd toe
        Sclerosis of the middle phalanx of the 3rd toe
        Patchy sclerosis of the middle phalanx of the 3rd toe
        Sclerosis of the middle phalanx of the 4th toe
        Patchy sclerosis of the middle phalanx of the 4th toe
        Sclerosis of the middle phalanx of the 5th toe
        Patchy sclerosis of the middle phalanx of the 5th toe
        Sclerosis of the proximal phalanx of the hallux
        Patchy sclerosis of the proximal phalanx of the hallux
        Sclerosis of proximal toe phalanx
        Patchy sclerosis of proximal toe phalanx
        Sclerosis of the proximal phalanx of the 2nd toe
        Patchy sclerosis of the proximal phalanx of the 2nd toe
        Sclerosis of the proximal phalanx of the 3rd toe
        Patchy sclerosis of the proximal phalanx of the 3rd toe
        Sclerosis of the proximal phalanx of the 4th toe
        Patchy sclerosis of the proximal phalanx of the 4th toe
        Sclerosis of the proximal phalanx of the 5th toe
        Patchy sclerosis of the proximal phalanx of the 5th toe

Recent clinical studies

Etiology

The Role of Angiogenesis Factors in the Formation of Vascular Changes in Scleroderma by Assessment of the Concentrations of VEGF and sVEGFR2 in Blood Serum and Tear Fluid.

Waszczykowska A, Goś R, Waszczykowska E, Dziankowska-Bartkowiak B, Podgórski M, Jurowski P
Mediators Inflamm 2020;2020:7649480. Epub 2020 Jan 24 doi: 10.1155/2020/7649480. PMID: 32410862 Free PMC Article

Digital Ulcers in Systemic Sclerosis - Frequency, Subtype Distribution and Clinical Outcome.

Lambova S, Batalov A, Sapundzhiev L, Müller-Ladner U
Curr Rheumatol Rev 2013;9(4):268-73. doi: 10.2174/157339710904140417125627. PMID: 26932292

Second toe swelling: Nora's lesion or glomus tumour, case report and literature review.

Mohammad A, Kilcoyne A, Blake S, Phelan M
Ir J Med Sci 2012 Sep;181(3):357-60. Epub 2009 Oct 8 doi: 10.1007/s11845-009-0435-0. PMID: 19813049

See all (3)

Diagnosis

Second toe swelling: Nora's lesion or glomus tumour, case report and literature review.

Mohammad A, Kilcoyne A, Blake S, Phelan M
Ir J Med Sci 2012 Sep;181(3):357-60. Epub 2009 Oct 8 doi: 10.1007/s11845-009-0435-0. PMID: 19813049

Osteoid osteoma of the great toe.

Hattori H, Takase K, Morohashi A
Orthopedics 2011 Aug 8;34(8):e432-5. doi: 10.3928/01477447-20110627-33. PMID: 21815591

Digital ischemic necrosis in a patient with systemic sclerosis: the role of laser Doppler perfusion imaging.

Rosato E, Roumpedaki E, Pisarri S, Salsano F
Vasa 2009 Nov;38(4):390-3. doi: 10.1024/0301-1526.38.4.390. PMID: 19998261

Chondrosarcoma of the distal phalanx of the great toe.

Hatori M, Watanabe M, Kokubun S
J Am Podiatr Med Assoc 2007 Mar-Apr;97(2):156-9. doi: 10.7547/0970156. PMID: 17369324

Acrorenal syndrome in an adult--presentation with proteinuria, hypertension, and glomerular lesions.

Zeier M, Tariverdian G, Waldherr R, Andrassy K, Ritz E
Am J Kidney Dis 1989 Sep;14(3):221-4. doi: 10.1016/s0272-6386(89)80075-7. PMID: 2773925

See all (5)

Therapy

Osteoid osteoma of the great toe.

Hattori H, Takase K, Morohashi A
Orthopedics 2011 Aug 8;34(8):e432-5. doi: 10.3928/01477447-20110627-33. PMID: 21815591

See all (1)

Clinical prediction guides

Digital Ulcers in Systemic Sclerosis - Frequency, Subtype Distribution and Clinical Outcome.

Lambova S, Batalov A, Sapundzhiev L, Müller-Ladner U
Curr Rheumatol Rev 2013;9(4):268-73. doi: 10.2174/157339710904140417125627. PMID: 26932292

See all (1)

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Sclerosis of toe phalanx

Definition

Term Hierarchy

Recent clinical studies

Etiology

Diagnosis

Therapy

Clinical prediction guides

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